2024
Biomarkers of Kidney Disease Progression in ADPKD
Ghanem A, Borghol A, Debeh F, Paul S, AlKhatib B, Harris P, Garimella P, Hanna C, Kline T, Dahl N, Chebib F. Biomarkers of Kidney Disease Progression in ADPKD. Kidney International Reports 2024, 9: 2860-2882. PMID: 39435347, PMCID: PMC11492289, DOI: 10.1016/j.ekir.2024.07.012.Peer-Reviewed Original ResearchAutosomal dominant polycystic kidney diseaseDominant polycystic kidney diseaseKidney disease progressionPolycystic kidney diseaseDisease progressionMonogenic kidney disorderKidney diseaseHeight-adjusted total kidney volumeDisease severityTotal kidney volumePKD1 geneGlomerular filtration rateMayo imaging classificationBody mass indexPersonalized treatment strategiesIncreased kidney sizePathogenic variantsEfficacy of treatmentAssess disease severityTotal cyst volumeGenetic profileImprove patient outcomesPredictive biomarkersCyst volumeKidney volume
2022
Chapter 36 Nutritional prevention and treatment of urinary tract stones* * We are indebted to Dr. Marvin Grieff and Dr. David Bushinsky who wrote the previous edition of this chapter.
Dahl N, Goldfarb D. Chapter 36 Nutritional prevention and treatment of urinary tract stones* * We are indebted to Dr. Marvin Grieff and Dr. David Bushinsky who wrote the previous edition of this chapter. 2022, 685-697. DOI: 10.1016/b978-0-12-818540-7.00046-x.Peer-Reviewed Original ResearchCoronary artery diseaseCalcium-containing stonesKidney stonesMetabolic syndromeDietary guidelinesLow bone mineral densityHigh blood pressureVitamin B6 intakeAmerican Urologic AssociationUS Dietary GuidelinesBone mineral densityHigh sucrose intakeUrinary tract stonesAccompanying comorbiditiesArtery diseaseBlood pressureB6 intakeBone healthSignificant morbidityVascular calcificationVitamin DAmericans 2015Sucrose intakeDisease progressionMineral density
2015
Total Kidney Volume in Autosomal Dominant Polycystic Kidney Disease: A Biomarker of Disease Progression and Therapeutic Efficacy
Alam A, Dahl NK, Lipschutz JH, Rossetti S, Smith P, Sapir D, Weinstein J, McFarlane P, Bichet DG. Total Kidney Volume in Autosomal Dominant Polycystic Kidney Disease: A Biomarker of Disease Progression and Therapeutic Efficacy. American Journal Of Kidney Diseases 2015, 66: 564-576. PMID: 25960302, DOI: 10.1053/j.ajkd.2015.01.030.Peer-Reviewed Original ResearchConceptsTotal kidney volumeAutosomal dominant polycystic kidney diseaseDisease progressionKidney enlargementKidney functionClinical trialsKidney volumeEnd pointAutosomal dominant polycystic kidneyKidney function measuresPrognostic end pointProgressive kidney enlargementEfficacy end pointGlomerular filtration rateDominant polycystic kidney diseasePolycystic kidney diseaseFluid-filled cystsKidney diseaseFiltration rateCurrent evidencePolycystic kidneysCyst growthFibrotic tissueTherapeutic efficacyTherapeutic interventions