2024
Risk Prediction for Atherosclerotic Cardiovascular Disease With and Without Race Stratification
Ghosh A, Venkatraman S, Nanna M, Safford M, Colantonio L, Brown T, Pinheiro L, Peterson E, Navar A, Sterling M, Soroka O, Nahid M, Banerjee S, Goyal P. Risk Prediction for Atherosclerotic Cardiovascular Disease With and Without Race Stratification. JAMA Cardiology 2024, 9: 55-62. PMID: 38055247, PMCID: PMC10701663, DOI: 10.1001/jamacardio.2023.4520.Peer-Reviewed Original ResearchConceptsLipoprotein cholesterol levelsAtherosclerotic cardiovascular diseaseCohort studyREGARDS cohortCholesterol levelsCardiovascular diseaseLow-density lipoprotein cholesterol levelsCoronary heart disease deathDensity lipoprotein cholesterol levelsRace-sex stratumHeart disease deathProspective cohort studyCohort risk equationsRisk predictionRace stratificationIncident ASCVDNonfatal strokeDisease deathsC-statisticMyocardial infarctionHigh riskRisk equationsSocial determinantsPercentage declineIncremental value
2020
Can the Absence of Hypertension Refine the Risk Assessment of Older Adults for Future Cardiovascular Events?
Nanna MG, Navar AM, Wojdyla D, Nelson AJ, Sullivan AE, Peterson ED. Can the Absence of Hypertension Refine the Risk Assessment of Older Adults for Future Cardiovascular Events? The American Journal Of Cardiology 2020, 142: 83-90. PMID: 33279483, PMCID: PMC8221431, DOI: 10.1016/j.amjcard.2020.11.027.Peer-Reviewed Original ResearchConceptsSystolic blood pressureAtherosclerotic cardiovascular diseaseAbsence of hypertensionBlood pressureCardiovascular diseaseCardiovascular eventsEvent ratesOlder adultsLower CVD event ratesLower systolic blood pressureASCVD event ratesCVD event ratesDiastolic blood pressureFuture cardiovascular eventsASCVD riskRisk stratificationPooled cohortMultivariable modelingHypertensionRisk scoreLower riskRisk estimatesNational InstituteObserved event ratesAdults
2019
The Accuracy of Cardiovascular Pooled Cohort Risk Estimates in U.S. Older Adults
Nanna MG, Peterson ED, Wojdyla D, Navar AM. The Accuracy of Cardiovascular Pooled Cohort Risk Estimates in U.S. Older Adults. Journal Of General Internal Medicine 2019, 35: 1701-1708. PMID: 31667745, PMCID: PMC7280419, DOI: 10.1007/s11606-019-05361-4.Peer-Reviewed Original ResearchConceptsAtherosclerotic cardiovascular diseaseOlder adultsACC/AHA guidelinesAge groupsLarge prospective cohort studyRisk estimatesYoung adultsASCVD risk estimationProspective cohort studyCardiovascular Health StudyHigh-risk groupU.S. older adultsDifferent age groupsCHD deathFramingham OriginalASCVD riskCardiovascular eventsAHA guidelinesCohort studyPrimary preventionCardiovascular diseaseRisk groupsTreatment decisionsFramingham OffspringHealth StudyThe Association Between Low‐Density Lipoprotein Cholesterol and Incident Atherosclerotic Cardiovascular Disease in Older Adults: Results From the National Institutes of Health Pooled Cohorts
Nanna MG, Navar AM, Wojdyla D, Peterson ED. The Association Between Low‐Density Lipoprotein Cholesterol and Incident Atherosclerotic Cardiovascular Disease in Older Adults: Results From the National Institutes of Health Pooled Cohorts. Journal Of The American Geriatrics Society 2019, 67: 2560-2567. PMID: 31411740, PMCID: PMC6898756, DOI: 10.1111/jgs.16123.Peer-Reviewed Original ResearchConceptsAtherosclerotic cardiovascular diseaseLow-density lipoprotein cholesterolIncident atherosclerotic cardiovascular diseaseRisk factorsEvent ratesLipoprotein cholesterolPooled cohortCardiovascular diseaseMultivariable-adjusted Cox proportional hazards modelsElevated low-density lipoprotein cholesterolIndividual level cohort dataCox proportional hazards modelOlder adultsASCVD event ratesCVD risk factorsCVD event ratesProspective cohort studyPresence of hyperlipidemiaProportional hazards modelNational InstituteCohort studyCVD riskMedian ageMedian LDLUnadjusted analyses
2018
Long-Term Cognitive Decline After Newly Diagnosed Heart Failure
Hammond CA, Blades NJ, Chaudhry SI, Dodson JA, Longstreth WT, Heckbert SR, Psaty BM, Arnold AM, Dublin S, Sitlani CM, Gardin JM, Thielke SM, Nanna MG, Gottesman RF, Newman AB, Thacker EL. Long-Term Cognitive Decline After Newly Diagnosed Heart Failure. Circulation Heart Failure 2018, 11: e004476. PMID: 29523517, PMCID: PMC6072263, DOI: 10.1161/circheartfailure.117.004476.Peer-Reviewed Original ResearchConceptsIncident heart failureHeart failureYears of ageEjection fractionHF diagnosisAtrial fibrillationModified Mini-Mental State Examination scoresCommunity-based prospective cohort studyCognitive declineHistory of HFMini-Mental State Examination scoreLong-term cognitive declineModified Mini-Mental State ExaminationAtrial fibrillation statusComorbid atrial fibrillationMini-Mental State ExaminationProspective cohort studyGlobal cognitive abilityState Examination scoreHospital discharge summariesPublic health implicationsCohort studyClinical strokeCardiovascular healthAdjusted model
2016
Carotid artery stenting versus carotid endarterectomy
Nanna MG, Gomes P, Njoh RF, Ward C, Attaran RR, Mena C. Carotid artery stenting versus carotid endarterectomy. Postgraduate Medical Journal 2016, 92: 532-539. PMID: 27317752, DOI: 10.1136/postgradmedj-2015-133689.Peer-Reviewed Original ResearchConceptsCarotid endarterectomyCarotid artery stentingCarotid artery stenosisArtery stentingMedical therapyArtery stenosisCarotid stenosisTreatment optionsSurgical techniqueTreatment strategiesCarotid arteryMajor causeEndarterectomyStenosisStrokeMorbidityStentingArterySignificant contributorOptionsTherapyMortalityTrials