How Imaging Glutamate, γ‐Aminobutyric Acid, and Dopamine Can Inform the Clinical Treatment of Alcohol Dependence and Withdrawal
Hillmer AT, Mason GF, Fucito LM, O'Malley SS, Cosgrove KP. How Imaging Glutamate, γ‐Aminobutyric Acid, and Dopamine Can Inform the Clinical Treatment of Alcohol Dependence and Withdrawal. Alcohol Clinical And Experimental Research 2015, 39: 2268-2282. PMID: 26510169, PMCID: PMC4712074, DOI: 10.1111/acer.12893.Peer-Reviewed Original ResearchMeSH KeywordsAlcoholismCross-Sectional StudiesDopamineGamma-Aminobutyric AcidGlutamic AcidHumansNeuroimagingSubstance Withdrawal SyndromeTreatment OutcomeConceptsAlcohol dependenceΓ-aminobutyric acidClinical treatmentMajor public health issuePublic health issuePositron emission tomographyRelapse prevention strategiesSingle photon emissionSpecific imaging modalityAlcohol withdrawalTobacco smokingGABA systemNeurotransmitter systemsNeurochemical basisPrevention strategiesDopaminergic functioningEmission tomographyHealth issuesImaging modalitiesWithdrawalSex differencesImaging literatureDopamineTomographyGlutamateInteractive and Indirect Effects of Anxiety and Negative Urgency on Alcohol‐Related Problems
Menary KR, Corbin WR, Leeman RF, Fucito LM, Toll BA, DeMartini K, O'Malley SS. Interactive and Indirect Effects of Anxiety and Negative Urgency on Alcohol‐Related Problems. Alcohol Clinical And Experimental Research 2015, 39: 1267-1274. PMID: 26031346, PMCID: PMC4490982, DOI: 10.1111/acer.12762.Peer-Reviewed Original ResearchMeSH KeywordsAdaptation, PsychologicalAlcohol-Related DisordersAnxietyCross-Sectional StudiesFemaleHumansMaleMotivationRandomized Controlled Trials as TopicYoung AdultConceptsNegative urgencyAlcohol problemsPotential moderatorsCoping-related drinking motivesDependence symptomsPrevention/intervention effortsNegative emotional statesIndirect effectsInteractive effectsAlcohol-related problemsCurrent cross-sectional studyAlcohol use disorderNegative affectDrinking motivesEmotional statesDrinking sampleModeration hypothesisIntervention effortsDirect interactive effectsAnxietyYoung adultsUse disordersLongitudinal dataModeratorPositive association