2024
Adoption of a gastroenterology hospitalist model and the impact on inpatient endoscopic practice volume: a controlled interrupted time-series analysis
Shung D, Li D, You K, Hung K, Laine L, Hughes M. Adoption of a gastroenterology hospitalist model and the impact on inpatient endoscopic practice volume: a controlled interrupted time-series analysis. IGIE 2024, 3: 329-332.e2. DOI: 10.1016/j.igie.2024.04.008.Peer-Reviewed Original ResearchControlled interrupted time series analysisHospitalist modelInterrupted time series analysisHigh-acuity hospitalAcademic health systemEndoscopy capacityInpatient coverageOutpatient providersProvider familiarityOutpatient careHealth systemWeekly volumeEndoscopy volumeHospital systemPractice volumeTime series analysisProcedure volumeGI patientsHospitalAcademic centersProvidersGastroenterologySeries analysisPotential benefitsEndoscopic procedures
2022
Deprescription of aspirin for primary prevention is uncommon at discharge in hospitalised patients with gastrointestinal bleeding
Li D, Ong S, Hughes M, Hung K, Agarwal R, Alexis J, Damianos J, Sharma S, Pires J, Nanna M, Laine L. Deprescription of aspirin for primary prevention is uncommon at discharge in hospitalised patients with gastrointestinal bleeding. Alimentary Pharmacology & Therapeutics 2022, 57: 94-102. PMID: 36394111, DOI: 10.1111/apt.17278.Peer-Reviewed Original ResearchConceptsMajor adverse cardiovascular eventsGastrointestinal bleedingPrimary preventionCardiovascular eventsRisk of MACEYale-New Haven HospitalPrimary cardiovascular preventionAdverse cardiovascular eventsKaplan-Meier curvesLong-term outcomesRisk-benefit ratioLog-rank testAspirin 81Hospitalised patientsPrimary endpointSecondary endpointsCardiovascular preventionSubsequent hospitalisationMedian ageDeprescriptionHigh riskAspirinHospitalisationPatientsPrevention
2021
Adapting to the Challenge of Hospital-Based Care: The Evolving Role of Gastroenterology Hospitalists
Hughes ML, Li DK, Hung KW, Laine L. Adapting to the Challenge of Hospital-Based Care: The Evolving Role of Gastroenterology Hospitalists. The American Journal Of Gastroenterology 2021, 117: 361-363. PMID: 34904965, DOI: 10.14309/ajg.0000000000001585.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsImmune Checkpoint Inhibitor–associated Diarrhea and Colitis: A Systematic Review and Meta-analysis of Observational Studies
Tran AN, Wang M, Hundt M, Chugh R, Ohm J, Grimshaw A, Ciarleglio M, Hung KW, Proctor DD, Price CC, Laine L, Al-Bawardy B. Immune Checkpoint Inhibitor–associated Diarrhea and Colitis: A Systematic Review and Meta-analysis of Observational Studies. Journal Of Immunotherapy 2021, 44: 325-334. PMID: 34380976, DOI: 10.1097/cji.0000000000000383.Peer-Reviewed Original ResearchConceptsImmune checkpoint inhibitorsDiarrhea/colitisICI therapyCheckpoint inhibitorsObservational studyAnti-programmed cell death-1/Outcomes of ICISystematic reviewCell death-1/Permanent ICI discontinuationReal-world incidenceRemission of diarrheaRecurrence of symptomsDeath-1/Treatment of diarrheaRandom-effects modelICI discontinuationAdvanced malignanciesAppropriate patientsPrimary outcomeOverall incidenceAntigen-4Early treatmentColitisHigh risk