2014
Heterogeneity of neural mechanisms of response to pivotal response treatment
Ventola P, Yang DY, Friedman HE, Oosting D, Wolf J, Sukhodolsky DG, Pelphrey KA. Heterogeneity of neural mechanisms of response to pivotal response treatment. Brain Imaging And Behavior 2014, 9: 74-88. PMID: 25370452, PMCID: PMC4993028, DOI: 10.1007/s11682-014-9331-y.Peer-Reviewed Original ResearchConceptsPivotal Response TreatmentPosterior superior temporal sulcusFunctional magnetic resonance imagingAutism spectrum disorderNeural responsesResponse treatmentRight posterior superior temporal sulcusBiological motion perception taskDifferential neural responsesMotion perception taskSuperior temporal sulcusPerception taskTD childrenTemporal sulcusSocial perceptionBrain responsesNeural mechanismsSpectrum disorderSocial communicationNeural vulnerabilityNeural characteristicsNeural systemsVentral striatumReward systemSubcortical regions
2010
Neural signatures of autism
Kaiser MD, Hudac CM, Shultz S, Lee SM, Cheung C, Berken AM, Deen B, Pitskel NB, Sugrue DR, Voos AC, Saulnier CA, Ventola P, Wolf JM, Klin A, Vander Wyk B, Pelphrey KA. Neural signatures of autism. Proceedings Of The National Academy Of Sciences Of The United States Of America 2010, 107: 21223-21228. PMID: 21078973, PMCID: PMC3000300, DOI: 10.1073/pnas.1010412107.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderNeural signaturesBiological motionBrain responsesUnaffected siblingsDistinct brain responsesFunctional magnetic resonanceAreas of dysfunctionNature of disruptionTD childrenSpectrum disorderDisorder heterogeneityNeural systemsBrain circuitryBehavioral profileCompensatory activitySystem-level mechanismsTrait activityAutismChildrenIncreased genetic riskGenetic riskState activityNeuroendophenotypesDisorders