2023
The Histone Chaperone Network Is Highly Conserved in Physarum polycephalum
Poulet A, Rousselot E, Téletchéa S, Noirot C, Jacob Y, van Wolfswinkel J, Thiriet C, Duc C. The Histone Chaperone Network Is Highly Conserved in Physarum polycephalum. International Journal Of Molecular Sciences 2023, 24: 1051. PMID: 36674565, PMCID: PMC9864664, DOI: 10.3390/ijms24021051.Peer-Reviewed Original ResearchConceptsHistone chaperonesEukaryotic treeChaperone networkBranching eukaryotesChaperone interactionsYeast complexCellular lifeDiverse proteinsPlant kingdomChaperone expressionRNA sequencingChaperonesKey residuesFunctional domainsHistonesCell cycleS phaseChromatinPhysarum polycephalumPlantsDistinct patternsEukaryotesOrthologuesCladeConserved
2016
A widely employed germ cell marker is an ancient disordered protein with reproductive functions in diverse eukaryotes
Carmell M, Dokshin G, Skaletsky H, Hu Y, van Wolfswinkel J, Igarashi K, Bellott D, Nefedov M, Reddien P, Enders G, Uversky V, Mello C, Page D. A widely employed germ cell marker is an ancient disordered protein with reproductive functions in diverse eukaryotes. ELife 2016, 5: e19993. PMID: 27718356, PMCID: PMC5098910, DOI: 10.7554/elife.19993.Peer-Reviewed Original ResearchConceptsDedicated germlineMajor eukaryotic lineagesDNA damage repairGerm cell markersEukaryotic lineagesDiverse eukaryotesEukaryotic evolutionMulticellular organismsMulticellular animalsSexual reproductionEarly eukaryotesGenomic integrityPhylogenetic analysisAncient familyReproductive cellsDamage repairGene expressionEukaryotesHeritable genomeGerm cellsProteinStem cellsGCNAGermlineCell markers
2010
The role of small non-coding RNAs in genome stability and chromatin organization
van Wolfswinkel JC, Ketting RF. The role of small non-coding RNAs in genome stability and chromatin organization. Journal Of Cell Science 2010, 123: 1825-1839. PMID: 20484663, DOI: 10.1242/jcs.061713.Peer-Reviewed Original ResearchConceptsSmall non-coding RNAsNon-coding RNAsSmall-interfering RNAChromatin-related mechanismsPost-transcriptional regulationNew regulatory mechanismNon-coding RNAChromatin regulationGenome stabilityChromatin organizationRegulatory potentialGene expressionRegulatory mechanismsRNARNA contentInitial discoveryRegulationEukaryotesMicroRNAsMechanismExpressionCellsDiscovery