1999
A Salmonella protein antagonizes Rac-1 and Cdc42 to mediate host-cell recovery after bacterial invasion
Fu Y, Galán J. A Salmonella protein antagonizes Rac-1 and Cdc42 to mediate host-cell recovery after bacterial invasion. Nature 1999, 401: 293-297. PMID: 10499590, DOI: 10.1038/45829.Peer-Reviewed Original ResearchMeSH KeywordsActinsArginineBacterial AdhesionBacterial ProteinsCdc42 GTP-Binding Protein, Saccharomyces cerevisiaeCell Cycle ProteinsCell MembraneEscherichia coliGTPase-Activating ProteinsGTP-Binding ProteinsHumansJNK Mitogen-Activated Protein KinasesMAP Kinase Kinase 4Mitogen-Activated Protein Kinase KinasesMutationProtein KinasesProtein Tyrosine PhosphatasesProteinsRecombinant Fusion ProteinsSalmonella typhimuriumConceptsHost cell cytosolActin cytoskeletonType III secretion systemProtein secretion systemSpecialized protein secretion systemActin cytoskeleton reorganizationCell actin cytoskeletonActin cytoskeletal changesRho GTPase proteinsRac-1Bacterial effectorsEffector proteinsExchange factorGTPase proteinsSecretion systemSalmonella proteinsCytoskeletal changesCellular responsesCdc42ProteinInfected cellsBacterial invasionCytosolBacteriumSPTPSalmonella typhimurium Encodes a Putative Iron Transport System within the Centisome 63 Pathogenicity Island
Zhou D, Hardt W, Galán J. Salmonella typhimurium Encodes a Putative Iron Transport System within the Centisome 63 Pathogenicity Island. Infection And Immunity 1999, 67: 1974-1981. PMID: 10085045, PMCID: PMC96555, DOI: 10.1128/iai.67.4.1974-1981.1999.Peer-Reviewed Original ResearchConceptsIron transport systemPathogenicity islandGrowth defectMinimal mediumPutative periplasmic binding proteinFur-dependent mannerPutative iron transport systemApparent growth defectS. typhimurium chromosomePeriplasmic binding proteinATP-binding proteinIron uptake systemOpen reading frameWild-type S. typhimuriumIron-restricted environmentNucleotide compositionPutative permeasesTransport systemExtensive homologyABC transportersReading frameSalmonella typhimuriumVirulence phenotypesUptake systemBinding protein
1990
Cloning and characterization of the asd gene of Salmonella typhimurium: use in stable maintenance of recombinant plasmids in Salmonella vaccine strains
Galán J, Nakayama K, Curtiss R. Cloning and characterization of the asd gene of Salmonella typhimurium: use in stable maintenance of recombinant plasmids in Salmonella vaccine strains. Gene 1990, 94: 29-35. PMID: 2227450, DOI: 10.1016/0378-1119(90)90464-3.Peer-Reviewed Original Research