2024
ASSOCIATIONS OF ULTRA LONG-TERM VISIT-TO-VISIT BLOOD PRESSURE VARIABILITY SINCE CHILDHOOD WITH VASCULAR AGING IN MIDLIFE: A 30-YEAR PROSPECTIVE COHORT STUDY
Wang Y, -Ma A, Zhao P, Chu C, Du M, Wang D, Jia H, Hu G, Ma Q, Yan Y, Chang J, Delles C, Chen F, Mu J. ASSOCIATIONS OF ULTRA LONG-TERM VISIT-TO-VISIT BLOOD PRESSURE VARIABILITY SINCE CHILDHOOD WITH VASCULAR AGING IN MIDLIFE: A 30-YEAR PROSPECTIVE COHORT STUDY. Journal Of Hypertension 2024, 42: e11. DOI: 10.1097/01.hjh.0001019424.08488.b4.Peer-Reviewed Original ResearchLong-term BP variabilityPresence of carotid plaqueBlood pressureAverage real variabilityArterial stiffnessBP variabilityCarotid hypertrophyMean BPCarotid plaquesSubpopulation treatment effect pattern plot methodologyVascular agingFunctional arterial propertiesYears of follow-upAssociated with arterial stiffnessPredictor of cardiovascular diseaseHigher BP variabilityPredictor of cardiovascular outcomesLong-term blood pressureAssociated with riskExposure to BPParticipants aged 6Clinical characteristicsFollow-upCohort studyCardiovascular outcomesASSOCIATION OF LONG-TERM TIME IN TARGET RANGE FOR SYSTOLIC BLOOD PRESSURE SINCE CHILDHOOD WITH ARTERIAL STIFFNESS IN MIDLIFE: A 36-YEAR PROSPECTIVE COHORT STUDY
Wang Y, Qi H, Jia H, Wang D, Sun Y, Du M, Hu G, Man Z, Chu C, Chang J, Delles C, Zhang L, Mu J. ASSOCIATION OF LONG-TERM TIME IN TARGET RANGE FOR SYSTOLIC BLOOD PRESSURE SINCE CHILDHOOD WITH ARTERIAL STIFFNESS IN MIDLIFE: A 36-YEAR PROSPECTIVE COHORT STUDY. Journal Of Hypertension 2024, 42: e54. DOI: 10.1097/01.hjh.0001019768.43096.d1.Peer-Reviewed Original ResearchRisk of arterial stiffnessSystolic blood pressureOdds ratioDecreased riskArterial stiffness in adulthoodAssociated with adult hypertensionRisk factorsModifiable risk factorsAdolescents aged 6Arterial stiffnessBlood pressureYears of follow-upCardiovascular risk factorsTraditional cardiovascular risk factorsAssociated with arterial stiffnessElevated blood pressureLowest quartileSystolic blood pressure variabilityCohort studyAged 6MidlifeTarget rangeCardiovascular diseaseAdult hypertensionTime-in-target
2023
EARLY LIFE CARDIOVASCULAR RISK FACTOR TRAJECTORIES AND VASCULAR AGING IN MIDLIFE: A 30-YEAR PROSPECTIVE COHORT STUDY
Wang Y, Wang J, Du M, Zhang X, Chu C, Wang D, Liao Y, Ma Q, Jia H, Hu G, Yan Y, Sun Y, Chang J, Delles C, Lu Y, Mu J. EARLY LIFE CARDIOVASCULAR RISK FACTOR TRAJECTORIES AND VASCULAR AGING IN MIDLIFE: A 30-YEAR PROSPECTIVE COHORT STUDY. Journal Of Hypertension 2023, 41: e20. DOI: 10.1097/01.hjh.0000939064.62089.c3.Peer-Reviewed Original ResearchBrachial-ankle pulse wave velocityCarotid intima-media thicknessSystolic blood pressureBody mass indexIndividual cardiovascular risk factorsCardiovascular risk factorsVascular agingHeart rateRisk factorsHanzhong Adolescent Hypertension StudyDistinct BMI trajectoriesFunctional arterial propertiesRisk factor accumulationProspective cohort studyIntima-media thicknessPulse wave velocityRisk factor trajectoriesGroup-based trajectory modelingCardiovascular outcomesOngoing cohortCohort studyBlood pressureIndependent predictorsMass indexSBP trajectoriesAssociations of SGLT2 genetic polymorphisms with salt sensitivity, blood pressure changes and hypertension incidence in Chinese adults
Jia H, Bao P, Yao S, Zhang X, Mu J, Hu G, Du M, Chu C, Zhang X, Wang L, Liao Y, Wang D, Ma Q, Yan Y, Niu Z, Gao W, Li H, Wu G, Chang J, Wang Y. Associations of SGLT2 genetic polymorphisms with salt sensitivity, blood pressure changes and hypertension incidence in Chinese adults. Hypertension Research 2023, 46: 1795-1803. PMID: 37160967, DOI: 10.1038/s41440-023-01301-2.Peer-Reviewed Original ResearchConceptsLongitudinal BP changesLow-salt dietDevelopment of hypertensionBlood pressureHypertension incidenceBP changesSodium-glucose cotransporter 2 inhibitorsSalt sensitivityCotransporter 2 inhibitorsIncidence of hypertensionHigh-salt dietSystolic blood pressureBlood pressure changesGenetic polymorphismsIncident hypertensionSystolic BPDietary interventionSBP changeUsual dietHypertensionChinese adultsSalutary effectsIncidenceDietSGLT2