2014
The mechanism of Torsin ATPase activation
Brown RS, Zhao C, Chase AR, Wang J, Schlieker C. The mechanism of Torsin ATPase activation. Proceedings Of The National Academy Of Sciences Of The United States Of America 2014, 111: e4822-e4831. PMID: 25352667, PMCID: PMC4234599, DOI: 10.1073/pnas.1415271111.Peer-Reviewed Original Research
2010
Structural insight into the mechanisms of enveloped virus tethering by tetherin
Yang H, Wang J, Jia X, McNatt MW, Zang T, Pan B, Meng W, Wang HW, Bieniasz PD, Xiong Y. Structural insight into the mechanisms of enveloped virus tethering by tetherin. Proceedings Of The National Academy Of Sciences Of The United States Of America 2010, 107: 18428-18432. PMID: 20940320, PMCID: PMC2972963, DOI: 10.1073/pnas.1011485107.Peer-Reviewed Original ResearchAntigens, CDBase SequenceCell LineCrystallography, X-RayDimerizationDNA PrimersGPI-Linked ProteinsHIV-1HumansImmunity, InnateIn Vitro TechniquesModels, MolecularMolecular Dynamics SimulationMutagenesis, Site-DirectedMutant ProteinsProtein StabilityProtein Structure, QuaternaryProtein Structure, TertiaryRecombinant ProteinsStatic ElectricityVirus ReleaseHeterohexameric Ring Arrangement of the Eukaryotic Proteasomal ATPases: Implications for Proteasome Structure and Assembly
Tomko RJ, Funakoshi M, Schneider K, Wang J, Hochstrasser M. Heterohexameric Ring Arrangement of the Eukaryotic Proteasomal ATPases: Implications for Proteasome Structure and Assembly. Molecular Cell 2010, 38: 393-403. PMID: 20471945, PMCID: PMC2879271, DOI: 10.1016/j.molcel.2010.02.035.Peer-Reviewed Original Research
2008
A regulatable switch mediates self-association in an immunoglobulin fold
Calabrese MF, Eakin CM, Wang JM, Miranker AD. A regulatable switch mediates self-association in an immunoglobulin fold. Nature Structural & Molecular Biology 2008, 15: 965-971. PMID: 19172750, PMCID: PMC2680708, DOI: 10.1038/nsmb.1483.Peer-Reviewed Original ResearchMeSH KeywordsAmyloidAmyloidosisBeta 2-MicroglobulinCopperCrystallography, X-RayElectron Spin Resonance SpectroscopyHumansHydrophobic and Hydrophilic InteractionsImmunoglobulinsIn Vitro TechniquesModels, BiologicalModels, MolecularMultiprotein ComplexesProtein FoldingProtein Interaction Domains and MotifsProtein Structure, QuaternaryRenal Dialysis
2005
Correction of X‐ray intensities from an HslV–HslU co‐crystal containing lattice‐translocation defects
Wang J, Rho SH, Park HH, Eom SH. Correction of X‐ray intensities from an HslV–HslU co‐crystal containing lattice‐translocation defects. Acta Crystallographica Section D, Structural Biology 2005, 61: 932-941. PMID: 15983416, DOI: 10.1107/s0907444905009546.Peer-Reviewed Original Research
2003
A second response in correcting the HslV–HslU quaternary structure
Wang J. A second response in correcting the HslV–HslU quaternary structure. Journal Of Structural Biology 2003, 141: 7-8. PMID: 12576015, DOI: 10.1016/s1047-8477(02)00629-9.Peer-Reviewed Original Research
2001
A Corrected Quaternary Arrangement of the Peptidase HslV and ATPase HslU in a Cocrystal Structure
Wang J. A Corrected Quaternary Arrangement of the Peptidase HslV and ATPase HslU in a Cocrystal Structure. Journal Of Structural Biology 2001, 134: 15-24. PMID: 11469873, DOI: 10.1006/jsbi.2001.4347.Peer-Reviewed Original ResearchConceptsQuaternary arrangementATP-dependent HslVU proteaseHslV peptidaseTranslocation poreHslU ATPaseHslVU proteaseHexameric ringHslVCocrystal structureHslUSmall-angle X-ray scattering (SAXS) studiesCrystal structurePeptidaseATPaseCrystallographic analysisElectron microscopic studySpace group assignmentX-ray scattering studyBindsHexamerProtease
2000
Sulfolobus shibatae CCA-adding enzyme forms a tetramer upon binding two tRNA molecules: a scrunching-shuttling model of CCA specificity1 1Edited by T. Richmond
Li F, Wang J, Steitz T. Sulfolobus shibatae CCA-adding enzyme forms a tetramer upon binding two tRNA molecules: a scrunching-shuttling model of CCA specificity1 1Edited by T. Richmond. Journal Of Molecular Biology 2000, 304: 483-492. PMID: 11090289, DOI: 10.1006/jmbi.2000.4189.Peer-Reviewed Original ResearchConceptsActive siteMulti-angle laser lightSmall-angle X-ray scatteringSize exclusion chromatographyX-ray scatteringFurther dimerizationExclusion chromatographyMoleculesDimeric enzymeC basesOligomerization stateTetramerTransfer RNA moleculesLaser lightTRNA moleculesRNA moleculesMonomersPrimer strandChromatographyEnzymeDimersHigh specificityBindingCCA-adding enzymeDimerization