2015
Estimation of the quality of refined protein crystal structures
Wang J. Estimation of the quality of refined protein crystal structures. Protein Science 2015, 24: 661-669. PMID: 25581292, PMCID: PMC4420517, DOI: 10.1002/pro.2639.Peer-Reviewed Original Research
1994
Structure of the binding site for nonnucleoside inhibitors of the reverse transcriptase of human immunodeficiency virus type 1.
Smerdon S, Jäger J, Wang J, Kohlstaedt L, Chirino A, Friedman J, Rice P, Steitz T. Structure of the binding site for nonnucleoside inhibitors of the reverse transcriptase of human immunodeficiency virus type 1. Proceedings Of The National Academy Of Sciences Of The United States Of America 1994, 91: 3911-3915. PMID: 7513427, PMCID: PMC43692, DOI: 10.1073/pnas.91.9.3911.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAntiviral AgentsBinding SitesCrystallography, X-RayDrug Resistance, MicrobialHIV Reverse TranscriptaseHIV-1Models, MolecularMolecular Sequence DataMolecular StructureNevirapineNucleosidesProtein Structure, TertiaryPyridinesReverse Transcriptase InhibitorsRNA-Directed DNA PolymeraseConceptsHuman immunodeficiency virus type 1Immunodeficiency virus type 1Drug resistance mutationsVirus type 1Type 1Reverse transcriptaseHIV-1 reverse transcriptaseNevirapineResistance mutationsNonnucleoside inhibitorsDrugsViable virusSpecific inhibitorInhibitorsClose contactMutationsTranscriptaseSame binding site
1993
Two DNA polymerases: HIV reverse transcriptase and the Klenow fragment of Escherichia coli DNA polymerase I.
Steitz T, Smerdon S, Jäger J, Wang J, Kohlstaedt L, Friedman J, Beese L, Rice P. Two DNA polymerases: HIV reverse transcriptase and the Klenow fragment of Escherichia coli DNA polymerase I. Cold Spring Harbor Symposia On Quantitative Biology 1993, 58: 495-504. PMID: 7525146, DOI: 10.1101/sqb.1993.058.01.056.Peer-Reviewed Original Research
1992
Crystal Structure at 3.5 Å Resolution of HIV-1 Reverse Transcriptase Complexed with an Inhibitor
Kohlstaedt L, Wang J, Friedman J, Rice P, Steitz T. Crystal Structure at 3.5 Å Resolution of HIV-1 Reverse Transcriptase Complexed with an Inhibitor. Science 1992, 256: 1783-1790. PMID: 1377403, DOI: 10.1126/science.1377403.Peer-Reviewed Original Research