2020
Emerging technologies to study glial cells
Hirbec H, Déglon N, Foo LC, Goshen I, Grutzendler J, Hangen E, Kreisel T, Linck N, Muffat J, Regio S, Rion S, Escartin C. Emerging technologies to study glial cells. Glia 2020, 68: 1692-1728. PMID: 31958188, DOI: 10.1002/glia.23780.Peer-Reviewed Original ResearchConceptsCell typesChallenging biological questionsGlial cellsSpecific cell typesDifferent glial cell typesGlial cell typesBiological questionsPhysiological functionsPrecursor cellsTight interactionOligodendrocyte precursor cellsCellsExperimental approachRelative contributionBrain functionFull understandingSpecific brain functionsRoleFunctionInteractionDevelopmentTranslation
2014
Modulation of oligodendrocyte generation during a critical temporal window after NG2 cell division
Hill RA, Patel KD, Goncalves CM, Grutzendler J, Nishiyama A. Modulation of oligodendrocyte generation during a critical temporal window after NG2 cell division. Nature Neuroscience 2014, 17: 1518-1527. PMID: 25262495, PMCID: PMC4275302, DOI: 10.1038/nn.3815.Peer-Reviewed Original Research
2013
Perturbed neural activity disrupts cerebral angiogenesis during a postnatal critical period
Whiteus C, Freitas C, Grutzendler J. Perturbed neural activity disrupts cerebral angiogenesis during a postnatal critical period. Nature 2013, 505: 407-411. PMID: 24305053, PMCID: PMC3947100, DOI: 10.1038/nature12821.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnimals, NewbornBlood VesselsCapillariesCell ProliferationCerebral CortexCerebrovascular CirculationDendritic SpinesEndothelial CellsFemaleHypoxia, BrainInterneuronsMaleMiceMicrocirculationNeovascularization, PathologicNeovascularization, PhysiologicNeurogliaNeuronsNG-Nitroarginine Methyl EsterNitric OxideNitric Oxide SynthaseOxygenSignal TransductionTime FactorsVibrissae
2001
Two modes of radial migration in early development of the cerebral cortex
Nadarajah B, Brunstrom J, Grutzendler J, Wong R, Pearlman A. Two modes of radial migration in early development of the cerebral cortex. Nature Neuroscience 2001, 4: 143-150. PMID: 11175874, DOI: 10.1038/83967.Peer-Reviewed Original ResearchConceptsCerebral cortexAcute cortical slicesCertain genetic mutationsFinal laminar positionSite of originMovement of neuronsCortical slicesCortical neuronsRadial migrationCortical developmentLaminar positionSomal translocationGenetic mutationsCell-type specificDifferential effectsEarly ageCortexNeuronsMarginal zoneLeading processCellsTranslocationEarly developmentTime-lapse imaging