1986
Augmentation of neutral sodium chloride absorption by increased flow rate in rat ileum in vivo.
Harris M, Dobbins J, Binder H. Augmentation of neutral sodium chloride absorption by increased flow rate in rat ileum in vivo. Journal Of Clinical Investigation 1986, 78: 431-438. PMID: 3734099, PMCID: PMC423573, DOI: 10.1172/jci112594.Peer-Reviewed Original ResearchConceptsNeutral sodium chloride absorptionSodium chloride absorptionRat ileumChloride absorptionIntraluminal volumeAddition of furosemideTransmural potential differenceSingle-pass perfusionOutflow tubingIntraluminal pressureSodium absorptionPerfusion mediumIntact animalsElectrolyte absorptionIleumElectrolyte transportRinger's solutionIncreased ratesPerfusion rateRemoval of sodiumStepwise increaseMinimal changesSeparate experimentsUnstirred layer thicknessSolute absorptionIon transport in proximal colon of the rat. Sodium depletion stimulates neutral sodium chloride absorption.
Foster E, Budinger M, Hayslett J, Binder H. Ion transport in proximal colon of the rat. Sodium depletion stimulates neutral sodium chloride absorption. Journal Of Clinical Investigation 1986, 77: 228-235. PMID: 2418060, PMCID: PMC423331, DOI: 10.1172/jci112281.Peer-Reviewed Original ResearchMeSH Keywords4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid4,4'-Diisothiocyanostilbene-2,2'-Disulfonic AcidAcetazolamideAmilorideAnimalsBiological Transport, ActiveColonHyperaldosteronismIntestinal AbsorptionIntestinal MucosaIon ChannelsMaleRatsRats, Inbred StrainsSodium ChlorideTheophyllineConceptsMu eq/hSodium-hydrogen exchangeProximal colonSodium depletionSodium absorptionDistal colonNeutral sodium chloride absorptionDistal segmentsAmiloride-sensitive sodium absorptionNet sodium absorptionSodium-depleted ratsRat distal colonSodium chloride absorptionNeutral sodium absorptionHydrogen ion secretionSecondary hyperaldosteronismParallel fallRat colonControl groupMM amilorideMucosal amilorideJNanetColonIon secretionChloride absorption
1983
Role of calcium in the regulation of colonic secretion in the rat
Zimmerman T, Dobbins J, Binder H. Role of calcium in the regulation of colonic secretion in the rat. American Journal Of Physiology 1983, 244: g552-g560. PMID: 6133455, DOI: 10.1152/ajpgi.1983.244.5.g552.Peer-Reviewed Original ResearchConceptsSerosal calciumRole of calciumExtracellular calciumElectrolyte transportNeutral sodium chloride absorptionEffect of bethanecholEffect of theophyllineMuscarinic cholinergic agonistNet sodium absorptionSodium chloride absorptionNet chloride absorptionCalcium-free mediumNeutral NaCl absorptionColonic secretionCholinergic agonistsIntracellular calciumBethanecholNet sodiumRat colonChloride secretionJNanetSodium absorptionChloride absorptionJClnetNaCl absorption