1985
The electrical basis for enhanced potassium secretion in rat distal colon during dietary potassium loading
Sandle G, Foster E, Lewis S, Binder H, Hayslett J. The electrical basis for enhanced potassium secretion in rat distal colon during dietary potassium loading. Pflügers Archiv - European Journal Of Physiology 1985, 403: 433-439. PMID: 2409517, DOI: 10.1007/bf00589258.Peer-Reviewed Original ResearchConceptsRat distal colonDistal colonPotassium secretionDietary potassium loadingPotassium channel blocker tetraethylammonium chlorideBasolateral membrane voltageChannel blocker tetraethylammonium chloridePotassium loadingSodium channel blocker amilorideActive potassium secretionElectrical basisEnhanced potassium secretionChannel blocker amilorideMembrane conductanceIntracellular potassium activityApical membrane resistanceMucosal additionPotassium-selective microelectrodesBasal conditionsControl tissuesTransepithelial voltageColonMembrane voltageSecretionTetraethylammonium chloride
1975
Effect of Shigella Enterotoxin on Electrolyte Transport in Rabbit Ileum
Donowitz M, Keusch G, Binder H. Effect of Shigella Enterotoxin on Electrolyte Transport in Rabbit Ileum. Gastroenterology 1975, 69: 1230-1237. PMID: 172398, DOI: 10.1016/s0016-5085(19)32315-7.Peer-Reviewed Original ResearchConceptsCyclic adenosine monophosphate levelsRabbit ileal mucosaIntestinal secretionShigella enterotoxinAdenosine monophosphate levelsElectrolyte secretionControl mucosaIleal mucosaCholera enterotoxinMonophosphate levelsNet sodium absorptionNet sodium secretionIntracellular cyclic adenosine monophosphate (cAMP) levelsAdenosine monophosphateEscherichia coli enterotoxinIntestinal waterUssing chambersRabbit ileumCyclic adenosine monophosphateSodium secretionMucosaSmall intestineSodium absorptionControl tissuesElectrolyte accumulation