1990
Hemodynamic events in a prospective randomized trial of propranolol versus placebo in the prevention of a first variceal hemorrhage
Groszmann R, Bosch J, Grace N, Conn H, Garcia-Tsao G, Navasa M, Alberts J, Rodes J, Fischer R, Bermann M, Rofe S, Patrick M, Lerner E. Hemodynamic events in a prospective randomized trial of propranolol versus placebo in the prevention of a first variceal hemorrhage. Gastroenterology 1990, 99: 1401-1407. PMID: 2210246, DOI: 10.1016/0016-5085(90)91168-6.Peer-Reviewed Original ResearchConceptsHepatic venous pressure gradientVenous pressure gradientVariceal hemorrhageEsophageal varicesHemodynamic eventsBaseline valuesHeart rateFirst variceal hemorrhagePropranolol-treated groupPropranolol-treated patientsTrial of propranololAdministration of propranololBeginning of therapyRate of survivalPortal hypertensionVariceal bleedingCirrhotic patientsPharmacological therapyVariceal sizeProtective effectMortality ratePatientsPlaceboPropranololVarices
1985
Portal pressure, presence of gastroesophageal varices and variceal bleeding
Garcia‐Tsao G, Groszmann R, Fisher R, Conn H, Atterbury C, Glickman M. Portal pressure, presence of gastroesophageal varices and variceal bleeding. Hepatology 1985, 5: 419-424. PMID: 3873388, DOI: 10.1002/hep.1840050313.Peer-Reviewed Original ResearchConceptsHepatic vein pressure gradientSmall varicesCirrhotic patientsPortal pressureLarge varicesSize of varicesHepatic vein catheterizationOccurrence of hemorrhagePortal pressure measurementsAlcoholic cirrhosisGastroesophageal varicesVariceal bleedingEsophagogastric varicesVariceal sizeVein catheterizationVaricesPatientsStandardized measurementsHgPressure measurementsCirrhosisBleedingCatheterizationHemorrhageEndoscopy