2022
Chemoattractant-Receptor Homologous Molecule on Th2 Cells (CRTH2) Regulates Neutrophilic Inflammation in the Lung
Jung E, Howell R, Cohen A, Tsang D, Chupp G, Dela Cruz C, Gautam S, Brewster R, Flint J, Yin H, Ristic N, Cosme Jr C. Chemoattractant-Receptor Homologous Molecule on Th2 Cells (CRTH2) Regulates Neutrophilic Inflammation in the Lung. 2022, a2534-a2534. DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2534.Peer-Reviewed Original Research
2004
Asthma: Mechanisms of Disease Persistence and Progression
Cohn L, Elias JA, Chupp GL. Asthma: Mechanisms of Disease Persistence and Progression. Annual Review Of Immunology 2004, 22: 789-815. PMID: 15032597, DOI: 10.1146/annurev.immunol.22.012703.104716.BooksConceptsIL-13Key effector cytokineAnti-inflammatory therapyIL-13 productionProduction of chemokinesProgression of diseaseAirway fibrosisAllergic asthmaAirway remodelingEffector cytokinesEosinophilic inflammationPersistent diseaseTh2 cytokinesEpithelial damageDisease progressionInflammatory responseTh2 cellsMucus productionSmooth muscleBronchial airwaysMatrix metalloproteinasesAnimal dataAsthmaDisease persistenceInflammation