2019
Biomarkers, Targeted Therapies, Biologics, and Bronchial Thermoplasty
Mohan A, Grace J, Mainardi A, Chupp G, Lugogo N. Biomarkers, Targeted Therapies, Biologics, and Bronchial Thermoplasty. Respiratory Medicine 2019, 123-153. DOI: 10.1007/978-3-030-20812-7_8.Peer-Reviewed Original ResearchSevere asthmaBronchial thermoplastyBiologic therapySurrogate markerOral corticosteroid exposureHeterogeneous inflammatory diseaseIdentification of respondersMultiple pathologic mechanismsAsthma controlCorticosteroid exposureDisease activityAsthma symptomsAsthma therapyPredictive markerInflammatory diseasesPrognostic markerTargeted therapyCurrent biomarkersPathologic mechanismsAsthmaDrug AdministrationParticular patientPatientsTherapyAdvanced therapies
2000
Osteopontin Expression Correlates with Clinical Outcome in Patients with Mycobacterial Infection
Nau G, Chupp G, Emile J, Jouanguy E, Berman J, Casanova J, Young R. Osteopontin Expression Correlates with Clinical Outcome in Patients with Mycobacterial Infection. American Journal Of Pathology 2000, 157: 37-42. PMID: 10880373, PMCID: PMC1850209, DOI: 10.1016/s0002-9440(10)64514-2.Peer-Reviewed Original ResearchConceptsInfected lymph nodesMycobacterial infectionOsteopontin expression correlatesLymph nodesClinical outcomesDisseminated infectionExpression correlatesBacillus Calmette-Guérin (BCG) vaccineMycobacterium bovis bacillus Calmette-Guérin (BCG) vaccineCalmette-Guérin vaccineBetter clinical outcomesChronic inflammatory diseaseSevere mycobacterial infectionsInterferon gamma receptor 1OPN protein expressionRegional adenitisImmune defectsInflammatory diseasesDisease progressionInflammatory responsePatientsReceptor 1InfectionOPN expressionProtein expression