2024
Living on the Edge: Role of Adjuvant Therapy After Resection of Primary Lung Cancer Within 2 Millimeters of a T-Stage Cutoff
Udelsman B, Bedrosian C, Kawaguchi E, Ding L, Wallace W, Rosenberg G, Harano T, Wightman S, Atay S, Kim A, Woodard G. Living on the Edge: Role of Adjuvant Therapy After Resection of Primary Lung Cancer Within 2 Millimeters of a T-Stage Cutoff. Journal Of Thoracic And Cardiovascular Surgery 2024 PMID: 39521371, DOI: 10.1016/j.jtcvs.2024.10.053.Peer-Reviewed Original ResearchNon-small cell lung cancerSystemic therapyOverall survivalT stageTumor sizeResected non-small cell lung cancerLung cancerNational Cancer Database of patientsResection of primary lung cancerOutcomes of systemic therapyPathologic tumor sizeNational Cancer DatabaseAdjuvant therapy useUse of systemic therapyPrimary lung cancerResection of tumorsCell lung cancerAssociated with decreased ratesDatabase of patientsRetrospective cohort studyTumor size distributionDownstaged patientsNodal involvementUnder-stagingAdjuvant therapy207 Spatial transcriptomic profiling non-small cell lung cancer reveals potential drivers of CTL exclusion and dysfunction, and identifies novel predictive biomarkers for checkpoint blockade therapy
Cho C, Lopez-Giraldez F, Huang B, He J, Woodard G, Badri T, Kidacki M, Vesely M, Wang G, Ofori-Ntiamoah G, Ng E, Chen L. 207 Spatial transcriptomic profiling non-small cell lung cancer reveals potential drivers of CTL exclusion and dysfunction, and identifies novel predictive biomarkers for checkpoint blockade therapy. 2024, a236-a236. DOI: 10.1136/jitc-2024-sitc2024.0207.Peer-Reviewed Original ResearchSex-based differences in CEACAM5 expression in lung cancer
Woodard G, Kane E, Todorovic N, Prince S, Dacic S, Chen L. Sex-based differences in CEACAM5 expression in lung cancer. Translational Cancer Research 2024, 13: 6394-6402. DOI: 10.21037/tcr-24-983.Peer-Reviewed Original ResearchAirway Esophageal Fistula
Koch K, Dhanasopon A, Woodard G. Airway Esophageal Fistula. Thoracic Surgery Clinics 2024, 34: 405-414. PMID: 39332865, DOI: 10.1016/j.thorsurg.2024.07.005.Peer-Reviewed Original ResearchConceptsTracheoesophageal fistulaManagement of tracheoesophageal fistulaTreating tracheoesophageal fistulaAcquired tracheoesophageal fistulaFistula tractDefinitive treatmentSurgical repairSurgical approachSurgical methodsPrevent recurrenceMuscle flapTracheal stentPathological connectionIntensive careImprove outcomesFistulaDiagnostic toolRepairEsophagealRecurrenceEsophagusStentFlapMA08.12 Semi-Sold Lung Nodule Growth Rates, Need for Treatment, and Cancer-Specific Verses All-Cause Mortality in a Large North American Population
Woodard G, Kane E, Prince S, Blasberg J, Dhanasopon A, Boffa D, Mase V, Dacic S, Bader A, Detterbeck F. MA08.12 Semi-Sold Lung Nodule Growth Rates, Need for Treatment, and Cancer-Specific Verses All-Cause Mortality in a Large North American Population. Journal Of Thoracic Oncology 2024, 19: s87. DOI: 10.1016/j.jtho.2024.09.156.Peer-Reviewed Original ResearchEP.07C.10 Real-World Outcomes of Patients Treated with Neoadjuvant Immunotherapy for Resectable Non-Small Cell Lung Cancer
Ermer T, Kim S, Goldberg S, Zolfaghari E, Blasberg J, Boffa D, Herbst R, Politi K, Schalper K, Dacic S, Woodard G. EP.07C.10 Real-World Outcomes of Patients Treated with Neoadjuvant Immunotherapy for Resectable Non-Small Cell Lung Cancer. Journal Of Thoracic Oncology 2024, 19: s543-s544. DOI: 10.1016/j.jtho.2024.09.1007.Peer-Reviewed Original ResearchMA04.12 Uncovering Disparities and Trends in Lung Cancer Screening Based on Patient Race and Insurance Status
Zolfaghari E, Tseng R, Sather P, Ermer T, Mase V, Detterbeck F, Tanoue L, Woodard G. MA04.12 Uncovering Disparities and Trends in Lung Cancer Screening Based on Patient Race and Insurance Status. Journal Of Thoracic Oncology 2024, 19: s68. DOI: 10.1016/j.jtho.2024.09.123.Peer-Reviewed Original ResearchSpatial Transcriptomics in Inflammatory Skin Diseases Using GeoMx Digital Spatial Profiling: A Practical Guide for Applications in Dermatology
Cho C, Haddadi N, Kidacki M, Woodard G, Shakiba S, Yıldız-Altay Ü, Richmond J, Vesely M. Spatial Transcriptomics in Inflammatory Skin Diseases Using GeoMx Digital Spatial Profiling: A Practical Guide for Applications in Dermatology. JID Innovations 2024, 5: 100317. PMID: 39559817, PMCID: PMC11570843, DOI: 10.1016/j.xjidi.2024.100317.Peer-Reviewed Original ResearchDigital spatial profilingInflammatory skin diseaseGeoMx Digital Spatial ProfilerSkin diseasesDiscoid lupus erythematosusNanoString GeoMx Digital Spatial ProfilingImmune milieuImmune microenvironmentLichen planusLupus erythematosusSingle cell RNA sequencingAberrant inflammationCell RNA sequencingSkin disease pathogenesisDisease pathogenesisManufacturer's guidelinesIndicators of diseaseDiseaseSpatial transcriptomics platformSkinTissue processingFurther insights into MARS 2
Zhan P, Boffa D, Woodard G. Further insights into MARS 2. The Lancet Respiratory Medicine 2024, 12: e52. PMID: 39214641, DOI: 10.1016/s2213-2600(24)00251-0.Peer-Reviewed Original ResearchShades of Gray: Do Never Smokers Benefit From Lung Cancer Screening Programs?
Woodard G, Jablons D. Shades of Gray: Do Never Smokers Benefit From Lung Cancer Screening Programs? Journal Of Thoracic Oncology 2024, 19: 1135-1137. PMID: 39111999, DOI: 10.1016/j.jtho.2024.06.007.Peer-Reviewed Original ResearchGender representation trends in cardiothoracic surgery journal editorial boards
Higaki A, Papageorge M, Waldron C, Huggins L, Brinker M, Erez E, Milewski R, Woodard G, Antonoff M, Lee M. Gender representation trends in cardiothoracic surgery journal editorial boards. Journal Of Thoracic And Cardiovascular Surgery 2024, 168: 1570-1580.e1. PMID: 38944272, DOI: 10.1016/j.jtcvs.2024.06.019.Peer-Reviewed Original ResearchThe Proposed Ninth Edition TNM Classification of Lung Cancer
Detterbeck F, Woodard G, Bader A, Dacic S, Grant M, Park H, Tanoue L. The Proposed Ninth Edition TNM Classification of Lung Cancer. CHEST Journal 2024, 166: 882-895. PMID: 38885896, DOI: 10.1016/j.chest.2024.05.026.Peer-Reviewed Original ResearchImage-guided and bronchoscopic localization techniques used to facilitate minimally invasive pulmonary metastasectomies
Wang A, Rosenberg G, Woodard G, Dhanasopon A, Udelsman B. Image-guided and bronchoscopic localization techniques used to facilitate minimally invasive pulmonary metastasectomies. Video-Assisted Thoracic Surgery 2024, 0: 0-0. DOI: 10.21037/vats-23-80.Peer-Reviewed Original ResearchShould the TNM Staging of NSCLC Evolve Beyond Anatomical Descriptors?
Woodard G, Dacic S. Should the TNM Staging of NSCLC Evolve Beyond Anatomical Descriptors? Journal Of Thoracic Oncology 2024, 19: 663-665. PMID: 38719420, DOI: 10.1016/j.jtho.2024.01.004.Peer-Reviewed Original ResearchChest Wall Anomaly Presenting as Pulmonary Nodule
Ely S, Van Udelsman B, Bader A, Woodard G. Chest Wall Anomaly Presenting as Pulmonary Nodule. Annals Of Thoracic Surgery Short Reports 2024, 2: 88-90. DOI: 10.1016/j.atssr.2023.11.021.Peer-Reviewed Original Research
2023
So Now We Know—Reflections on the Extent of Resection for Stage I Lung Cancer
Detterbeck F, Ely S, Udelsman B, Blasberg J, Boffa D, Dhanasopon A, Mase V, Woodard G. So Now We Know—Reflections on the Extent of Resection for Stage I Lung Cancer. Clinical Lung Cancer 2023, 25: e113-e123. PMID: 38310034, DOI: 10.1016/j.cllc.2023.12.007.Peer-Reviewed Original ResearchStage I lung cancerI lung cancerSublobar resectionRecurrence-free survivalHealthy patientsLung cancerRecent trialsInadequate resection marginsLarge recent trialsAdditional randomized trialsHigh-level evidenceOverall survival differenceExtent of resectionLong-term outcomesLong-term resultsHigh locoregional recurrenceAspects of patientsLesser resectionsLocoregional recurrencePerioperative morbidityIntraoperative detailsLung functionResection extentResection marginsPostoperative changesIncreased Lymphocyte Infiltration in NSCLC Neoadjuvant Chemo-Immunotherapy Non-responders: A Biomarker of T-Cell Dysfunction and Prognosis?
Woodard G, Cho C, Chen L. Increased Lymphocyte Infiltration in NSCLC Neoadjuvant Chemo-Immunotherapy Non-responders: A Biomarker of T-Cell Dysfunction and Prognosis? Annals Of Surgical Oncology 2023, 31: 25-27. PMID: 37899411, DOI: 10.1245/s10434-023-14388-1.Peer-Reviewed Original ResearchImpact of the COVID-19 Pandemic on Lung Cancer Screening Processes in a Northeast Tertiary Health Care Network
Udelsman B, Detterbeck F, Tanoue L, Mase V, Boffa D, Blasberg J, Dhanasopon A, Ely S, Mazzarelli L, Bader A, Woodard G. Impact of the COVID-19 Pandemic on Lung Cancer Screening Processes in a Northeast Tertiary Health Care Network. Journal Of Computer Assisted Tomography 2023, 48: 222-225. PMID: 37832536, DOI: 10.1097/rct.0000000000001549.Peer-Reviewed Original ResearchHealth care networkLung cancer screening processLung cancer screening programsCare networkCancer screening programsCoronavirus disease 2019 (COVID-19) pandemicComputed tomography scanCOVID-19 hospitalizationCOVID-19 surgeCancer screening processDisease 2019 pandemicLung cancer diagnosisHealth care systemAverage hospitalizationRadiology databaseLung cancerTomography scanScreening programCare systemCancer diagnosisMonthsHospitalizationCOVID-19COVID-19 pandemicPandemicBrief Report: Increasing Prevalence of Ground-Glass Nodules and Semisolid Lung Lesions on Outpatient Chest Computed Tomography Scans
Woodard G, Udelsman B, Prince S, Blasberg J, Dhanasopon A, Gange C, Traube L, Mase V, Boffa D, Detterbeck F, Bader A. Brief Report: Increasing Prevalence of Ground-Glass Nodules and Semisolid Lung Lesions on Outpatient Chest Computed Tomography Scans. JTO Clinical And Research Reports 2023, 4: 100583. PMID: 38074773, PMCID: PMC10709040, DOI: 10.1016/j.jtocrr.2023.100583.Peer-Reviewed Original ResearchGround-glass nodulesChest CT scanCT scanLung lesionsHealth systemLarge academic health systemAcademic health systemCross-sectional imagingRadiographic findingsPhysician consultationChest CTDatabase reviewTomography scanRadiographic lesionsAge groupsLesionsStudy periodLung nodulesOutpatient CTRadiology reportsAdult chestCTScansChestNodulesComparative genomics between matched solid and lepidic portions of semi-solid lung adenocarcinomas
Woodard G, Ding V, Cho C, Brand N, Kratz J, Jones K, Jablons D. Comparative genomics between matched solid and lepidic portions of semi-solid lung adenocarcinomas. Lung Cancer 2023, 180: 107211. PMID: 37121213, PMCID: PMC10900430, DOI: 10.1016/j.lungcan.2023.107211.Peer-Reviewed Original ResearchConceptsInvasive portionDriver mutationsSolid adenocarcinomaLung cancer driver mutationsNext-generation sequencingWarrants further studyLobar resectionClinical characteristicsSurgical databaseAsian patientsInvasive cancerPoor prognosisLung cancerLung lesionsInvasive componentInvasive solid tumorsNormal lungLepidicStage IPromising biomarkerSolid tumorsCancer developmentSame time periodGenes SPP1Gene expression