Using cryo-EM to measure the dipole potential of a lipid membrane
Wang L, Bose PS, Sigworth FJ. Using cryo-EM to measure the dipole potential of a lipid membrane. Proceedings Of The National Academy Of Sciences Of The United States Of America 2006, 103: 18528-18533. PMID: 17116859, PMCID: PMC1693696, DOI: 10.1073/pnas.0608714103.Peer-Reviewed Original ResearchMeSH KeywordsCryoelectron MicroscopyLipid BilayersLiposomesMembrane PotentialsOsmotic PressurePhosphatidylcholinesConceptsDipole potentialLipid membranesPhase-contrast imagingMolecular dynamics calculationsLipid bilayer membranesIon translocation ratesAtomic potentialLipid moleculesLipid monolayersBilayer membranesDynamics calculationsProbe methodSurface potentialAnionsDiphytanoylphosphatidylcholineCationsElectronsImage intensityAbsolute valueMembraneMoleculesConformationLarge permeabilityMonolayersBilayers