2000
Acetyl phosphate-dependent activation of a mutant PhoP response regulator that functions independently of its cognate sensor kinase11Edited by M. Gottesman
Chamnongpol S, Groisman E. Acetyl phosphate-dependent activation of a mutant PhoP response regulator that functions independently of its cognate sensor kinase11Edited by M. Gottesman. Journal Of Molecular Biology 2000, 300: 291-305. PMID: 10873466, DOI: 10.1006/jmbi.2000.3848.Peer-Reviewed Original ResearchMeSH KeywordsAllelesAmino Acid SubstitutionBacterial ProteinsEnvironmentGene Expression Regulation, BacterialGenes, BacterialGenes, RegulatorMagnesiumMembrane ProteinsMethyl-Accepting Chemotaxis ProteinsModels, MolecularMutationOperonOrganophosphatesPhosphorylationProtein BindingProtein BiosynthesisProtein Structure, TertiaryRecombinant Fusion ProteinsSalmonella entericaTrans-ActivatorsTranscription, GeneticConceptsTranscription of PhoPResponse regulatorAcetyl phosphateResponse regulator receiver domainSites of phosphorylationVirulence gene expressionPhoP response regulatorTwo-component systemPhoQ proteinPhoP proteinReceiver domainSensor kinaseTranscriptional repressionCognate sensorMutant proteinsM. GottesmanPhosphorylated stateAspartate residueGene expressionPhoPTranscriptionPhosphate donorRegulatorProteinSalmonella enterica
1998
The ins and outs of virulence gene expression: Mg2+ as a regulatory signal
Groisman E. The ins and outs of virulence gene expression: Mg2+ as a regulatory signal. BioEssays 1998, 20: 96-101. PMID: 9504051, DOI: 10.1002/(sici)1521-1878(199801)20:1<96::aid-bies13>3.0.co;2-3.Peer-Reviewed Original ResearchConceptsSignal transduction systemTransduction systemCellular locationPhoP/PhoQ systemPathogen Salmonella enterica serovar TyphimuriumIntracellular pathogen Salmonella enterica serovar TyphimuriumTranscription of genesPhoP/PhoQVirulence gene expressionFacultative intracellular pathogen Salmonella enterica serovar TyphimuriumSalmonella enterica serovar TyphimuriumDifferent cell typesRegulatory hierarchyEnterica serovar TyphimuriumRegulatory signalsExtracellular environmentGene expressionHost cellsHost cuesCell typesMultiple environmentsSerovar TyphimuriumPrecise tissuePhoQTranscription
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply