2004
Involvement of Salmonella Pathogenicity Island 2 in the Up-Regulation of Interleukin-10 Expression in Macrophages: Role of Protein Kinase A Signal Pathway
Uchiya K, Groisman EA, Nikai T. Involvement of Salmonella Pathogenicity Island 2 in the Up-Regulation of Interleukin-10 Expression in Macrophages: Role of Protein Kinase A Signal Pathway. Infection And Immunity 2004, 72: 1964-1973. PMID: 15039316, PMCID: PMC375175, DOI: 10.1128/iai.72.4.1964-1973.2004.Peer-Reviewed Original ResearchConceptsSalmonella pathogenicity island 2Pathogenicity island 2Wild-type SalmonellaCyclic AMP response element binding proteinPKA activityProtein kinase A (PKA) signal pathwaySPI-2Island 2Signal transduction pathwaysProtein kinase A (PKA) inhibitor HResponse element-binding proteinA (PKA) inhibitor HElement-binding proteinFacultative intracellular bacteriaAMP response element binding proteinTransduction pathwaysSpiC genePKA activationSpiC mutantIntracellular bacteriaInhibitor HSignal pathwayCREB phosphorylationUp-RegulationPhosphorylation
1999
A Salmonella virulence protein that inhibits cellular trafficking
Uchiya K, Barbieri M, Funato K, Shah A, Stahl P, Groisman E. A Salmonella virulence protein that inhibits cellular trafficking. The EMBO Journal 1999, 18: 3924-3933. PMID: 10406797, PMCID: PMC1171468, DOI: 10.1093/emboj/18.14.3924.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsBacterial ProteinsBiological TransportCell LineCell SurvivalCytosolEndosomesGenes, BacterialGTP-Binding ProteinsInhibitory Concentration 50Lethal Dose 50LysosomesMacrophagesMembrane FusionMiceMolecular Sequence DataMutationPhagosomesrab5 GTP-Binding ProteinsReceptors, TransferrinSalmonella entericaVirulenceConceptsType III secretion systemSecretion systemIntracellular traffickingSPI-2 pathogenicity islandTrafficking of vesiclesEndosome-endosome fusionHost cell cytosolVirulence proteinsCellular traffickingNormal traffickingSpiC geneCell cytosolPathogenicity islandSalmonella pathogenesisSpiC mutantTraffickingProteinInhibited fusionSindbis virusSalmonella entericaTransferrin receptorJ774 macrophagesMutantsEndosomesGenes
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply