2015
Salmonella promotes virulence by repressing cellulose production
Pontes MH, Lee EJ, Choi J, Groisman EA. Salmonella promotes virulence by repressing cellulose production. Proceedings Of The National Academy Of Sciences Of The United States Of America 2015, 112: 5183-5188. PMID: 25848006, PMCID: PMC4413311, DOI: 10.1073/pnas.1500989112.Peer-Reviewed Original ResearchConceptsCellulose synthesisWild-type phenotypeWild-type virulenceSalmonella enterica serovar TyphimuriumCyclic diguanylateEnterica serovar TyphimuriumPathogen fitnessAbundant organic polymerMgtC geneAcute virulenceAllosteric activatorAbiotic surfacesMgtC mutantInside macrophagesMutantsVirulence determinantsSerovar TyphimuriumVirulenceCellulose productionEnvironmental insultsCellulose levelsBCSAAttenuated mutantsTraitsDiguanylate
2002
Conflicting needs for a Salmonella hypervirulence gene in host and non‐host environments
Mouslim C, Hilbert F, Huang H, Groisman EA. Conflicting needs for a Salmonella hypervirulence gene in host and non‐host environments. Molecular Microbiology 2002, 45: 1019-1027. PMID: 12180921, DOI: 10.1046/j.1365-2958.2002.03070.x.Peer-Reviewed Original ResearchConceptsSole carbon sourceD-Ala-D-Ala dipeptidaseNon-host environmentsNutrient-poor conditionsPathogen Salmonella entericaCarbon sourceWild-type SalmonellaPathogen fitnessFaster growth rateGenesInfected hostHypervirulence genesMutantsInnate immunitySalmonella entericaDipeptidase activityGrowth rateHostInactivationPhenotypeFitnessDipeptidasePathogensSalmonellaEnterica