2014
Cardiovascular Magnetic Resonance Imaging of Scar Development Following Pulmonary Vein Isolation: A Prospective Study
Hsing J, Peters DC, Knowles BR, Manning WJ, Josephson ME. Cardiovascular Magnetic Resonance Imaging of Scar Development Following Pulmonary Vein Isolation: A Prospective Study. PLOS ONE 2014, 9: e104844. PMID: 25251403, PMCID: PMC4174508, DOI: 10.1371/journal.pone.0104844.Peer-Reviewed Original ResearchMeSH KeywordsAdultAtrial FibrillationCardiovascular SystemCatheter AblationCicatrixContrast MediaEdemaFemaleGadolinium DTPAHumansImage EnhancementLinear ModelsMagnetic Resonance ImagingMaleMiddle AgedProspective StudiesPulmonary VeinsRadiographyReproducibility of ResultsSensitivity and SpecificityTime FactorsConceptsPulmonary vein isolationCardiovascular magnetic resonanceVein isolationAtrial wall thicknessLGE enhancementLGE volumeCardiovascular magnetic resonance imagingVolume of LGEAtrial fibrillation patientsPattern of edemaSubsequent scar formationLate gadolinium enhancement (LGE) imagingMagnetic resonanceAtrial wall thickeningNon-invasive assessmentMagnetic resonance imagingEdema enhancementFibrillation patientsProspective studyPost ablationEarly edemaLGE scarScar formationEdemaResonance imaging
2013
Evaluation of current algorithms for segmentation of scar tissue from late Gadolinium enhancement cardiovascular magnetic resonance of the left atrium: an open-access grand challenge
Karim R, Housden RJ, Balasubramaniam M, Chen Z, Perry D, Uddin A, Al-Beyatti Y, Palkhi E, Acheampong P, Obom S, Hennemuth A, Lu Y, Bai W, Shi W, Gao Y, Peitgen HO, Radau P, Razavi R, Tannenbaum A, Rueckert D, Cates J, Schaeffter T, Peters D, MacLeod R, Rhode K. Evaluation of current algorithms for segmentation of scar tissue from late Gadolinium enhancement cardiovascular magnetic resonance of the left atrium: an open-access grand challenge. Journal Of Cardiovascular Magnetic Resonance 2013, 15: 105. PMID: 24359544, PMCID: PMC3878126, DOI: 10.1186/1532-429x-15-105.Peer-Reviewed Original ResearchConceptsRadio-frequency catheter ablationAtrial fibrillationTreatment of AFEnhancement cardiovascular magnetic resonance imagingLate gadolinium enhancement cardiovascular magnetic resonanceReference standardEnhancement cardiovascular magnetic resonanceCardiovascular magnetic resonance imagingPost-ablation imagesRegions of fibrosisAssessment of treatmentCardiovascular magnetic resonanceMagnetic resonance imagingPost-ablation imagingLA fibrosisCatheter ablationLGE CMR imagesCMR imagesLeft atriumTreatment stratificationScar tissueResonance imagingFibrosisStandardised evaluationKing's College London
2010
Late Gadolinium Enhancement of the Esophagus is Common on Cardiac MR Several Months after Pulmonary Vein Isolation: Preliminary Observations
MENG J, PETERS DC, HSING JM, CHUANG ML, CHAN J, FISH A, JOSEPHSON ME, MANNING WJ. Late Gadolinium Enhancement of the Esophagus is Common on Cardiac MR Several Months after Pulmonary Vein Isolation: Preliminary Observations. Pacing And Clinical Electrophysiology 2010, 33: 661-666. PMID: 20059713, DOI: 10.1111/j.1540-8159.2009.02671.x.Peer-Reviewed Original ResearchConceptsPulmonary vein isolationCardiovascular magnetic resonance imagingAtrial fibrillationVein isolationLGE-CMRPost-pulmonary vein isolationLate gadolinium enhancement cardiovascular magnetic resonance imagingEnhancement cardiovascular magnetic resonance imagingFrequent imaging findingsLeft atrium cavityLate gadolinium enhancementMagnetic resonance imagingEsophageal positionImaging findingsEsophageal locationGadolinium enhancementHyperenhancementNoninvasive assessmentVertebral bodyResonance imagingClinical implicationsAblation siteLonger ablation timePatientsCardiac MR
2009
Relationship between intended sites of RF ablation and post-procedural scar in AF patients, using late gadolinium enhancement cardiovascular magnetic resonance
Taclas JE, Nezafat R, Wylie JV, Josephson ME, Hsing J, Manning WJ, Peters DC. Relationship between intended sites of RF ablation and post-procedural scar in AF patients, using late gadolinium enhancement cardiovascular magnetic resonance. Heart Rhythm 2009, 7: 489-496. PMID: 20122877, PMCID: PMC2843771, DOI: 10.1016/j.hrthm.2009.12.007.Peer-Reviewed Original ResearchLeft ventricular infarct size, peri‐infarct zone, and papillary scar measurements: A comparison of high‐resolution 3D and conventional 2D late gadolinium enhancement cardiac MR
Peters DC, Appelbaum EA, Nezafat R, Dokhan B, Han Y, Kissinger KV, Goddu B, Manning WJ. Left ventricular infarct size, peri‐infarct zone, and papillary scar measurements: A comparison of high‐resolution 3D and conventional 2D late gadolinium enhancement cardiac MR. Journal Of Magnetic Resonance Imaging 2009, 30: 794-800. PMID: 19787731, PMCID: PMC2981352, DOI: 10.1002/jmri.21897.Peer-Reviewed Original ResearchRecurrence of Atrial Fibrillation Correlates With the Extent of Post-Procedural Late Gadolinium Enhancement A Pilot Study
Peters DC, Wylie JV, Hauser TH, Nezafat R, Han Y, Woo JJ, Taclas J, Kissinger KV, Goddu B, Josephson ME, Manning WJ. Recurrence of Atrial Fibrillation Correlates With the Extent of Post-Procedural Late Gadolinium Enhancement A Pilot Study. JACC Cardiovascular Imaging 2009, 2: 308-316. PMID: 19356576, PMCID: PMC2703450, DOI: 10.1016/j.jcmg.2008.10.016.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAtrial FibrillationCatheter AblationCicatrixContrast MediaFemaleGadolinium DTPAHeart AtriaHumansImage Interpretation, Computer-AssistedImaging, Three-DimensionalKaplan-Meier EstimateMagnetic Resonance ImagingMaleMiddle AgedPilot ProjectsPredictive Value of TestsProportional Hazards ModelsPulmonary VeinsRecurrenceRisk AssessmentTime FactorsTreatment FailureConceptsRight inferior pulmonary veinCardiac magnetic resonanceLGE cardiac magnetic resonanceRF ablation proceduresPulmonary veinsAF recurrenceAblation proceduresPV isolationLate gadolinium enhancement (LGE) CMRAtrial fibrillation correlatesBidirectional conduction blockAtrial fibrillation patientsInferior pulmonary veinExtent of scarringRadiofrequency ablation lesionsExtent of scarA Pilot StudyFirst yearRecurrent AFThirteen patientsFibrillation patientsParoxysmal AFPV ostiaProcedural successAtrial scarring
2008
Left atrial function and scar after catheter ablation of atrial fibrillation
Wylie JV, Peters DC, Essebag V, Manning WJ, Josephson ME, Hauser TH. Left atrial function and scar after catheter ablation of atrial fibrillation. Heart Rhythm 2008, 5: 656-662. PMID: 18452866, DOI: 10.1016/j.hrthm.2008.02.008.Peer-Reviewed Original ResearchConceptsAtrial systolic functionLA ejection fractionAtrial fibrillationCatheter ablationEjection fractionRadiofrequency ablationLeft atriumAF ablationSystolic functionLA functionCircumferential pulmonary vein isolationMaximum RA volumeRA ejection fractionCardiovascular magnetic resonance imagingPulmonary vein isolationLA scarPersistent atrial fibrillationMaximum LA volumeCine CMR imagingScar volumeMagnetic resonance imagingThromboembolic riskAtrial functionVein isolationConsecutive patients
2007
Detection of Pulmonary Vein and Left Atrial Scar after Catheter Ablation with Three-dimensional Navigator-gated Delayed Enhancement MR Imaging: Initial Experience
Peters DC, Wylie JV, Hauser TH, Kissinger KV, Botnar RM, Essebag V, Josephson ME, Manning WJ. Detection of Pulmonary Vein and Left Atrial Scar after Catheter Ablation with Three-dimensional Navigator-gated Delayed Enhancement MR Imaging: Initial Experience. Radiology 2007, 243: 690-5. PMID: 17517928, DOI: 10.1148/radiol.2433060417.Peer-Reviewed Original ResearchConceptsPulmonary veinsLeft atriumEnhancement MR imagingLeft inferior pulmonary veinMR imagingInferior pulmonary veinEnhancement magnetic resonance imagingLocal institutional review boardUnpaired t-testMagnetic resonance imagingInstitutional review boardIsolation therapyCatheter ablationAtrial fibrillationRadiofrequency ablationInteratrial septumAtrial wallEnhancement patternPatientsInitial experienceAtrial scarResonance imagingRF ablationMR imaging methodsInformed consent