2016
Sex Differences in Smoking Cessation Pharmacotherapy Comparative Efficacy: A Network Meta-analysis
Smith PH, Weinberger AH, Zhang J, Emme E, Mazure CM, McKee SA. Sex Differences in Smoking Cessation Pharmacotherapy Comparative Efficacy: A Network Meta-analysis. Nicotine & Tobacco Research 2016, 19: 273-281. PMID: 27613893, PMCID: PMC5939704, DOI: 10.1093/ntr/ntw144.Peer-Reviewed Original ResearchConceptsTransdermal nicotineSmoking cessationBupropion SRComparative efficacyFirst option treatmentSustained release bupropionPlacebo-controlled trialSex differencesCigarette smoking cessationNetwork Meta-AnalysisRelease bupropionCessation pharmacotherapyOption treatmentGeneral community sampleCigarette smokersQuit ratesVarenicline's efficacyPharmacological interventionsVareniclineBupropionNicotine addictionMeta-AnalysisPlaceboSimilar outcomesSignificant sex differences
1998
Management of the Adverse Effects of Clozapine
Young CR, Bowers MB, Mazure CM. Management of the Adverse Effects of Clozapine. Schizophrenia Bulletin 1998, 24: 381-390. PMID: 9718630, DOI: 10.1093/oxfordjournals.schbul.a033333.Peer-Reviewed Original ResearchConceptsAdverse effectsElevated liver enzymesPercent of patientsSuccessful pharmacological managementPositive therapeutic outcomesHypothesized pathophysiologyPharmacological managementRefractory schizophreniaNeuromuscular effectsTraditional neurolepticsLiver enzymesPharmacological interventionsClozapineAffective disordersTherapeutic outcomesNeurological disordersMental disordersMaximum doseObsessive-compulsive symptomsWeight gainDisordersPatientsPathophysiologyNew hopeTreatment