2024
Role of Vena Cava Filter in the Prophylaxis and Treatment of Venous Thromboembolism in Injured Adult Patients: A Systematic Review, Meta-Analysis, and Practice Management Guideline from the Eastern Association for the Surgery of Trauma [RETRACTED].
Bhattacharya B, Kodadek L, Nichiporenko I, Morrissey S, Kirsch J, Choi J, Ladhani H, Kasotakis G, Mukherjee K, Narsule C, Sharma R, Ruangvoravat L, Grushka J, Rattan R, Bugaev N. Role of Vena Cava Filter in the Prophylaxis and Treatment of Venous Thromboembolism in Injured Adult Patients: A Systematic Review, Meta-Analysis, and Practice Management Guideline from the Eastern Association for the Surgery of Trauma [RETRACTED]. Journal Of Trauma And Acute Care Surgery 2024 PMID: 38454308, DOI: 10.1097/ta.0000000000004289.Peer-Reviewed Original ResearchInferior vena cava filterInferior vena cavaQuality of evidenceDeep vein thrombosisInjured adult patientsRandomized controlled trialsVenous thromboembolismInjured patientsIVC filtersPulmonary embolismAdult patientsInferior vena cava filter useMeta-analysisEastern Association for the Surgery of TraumaTreatment of venous thromboembolismEvidence-based guidelinesPlacement of IVC filtersSystematic review/meta-analysisAcute venous thromboembolismVena cava filterPrevent venous thromboembolismPractice management guidelinesSurgery of TraumaLength of stayRecommendations AssessmentTo close or not to close? Wound management in emergent colorectal surgery, an EAST multicenter prospective cohort study
Feather C, Rehrig S, Allen R, Barth N, Kugler E, Cullinane D, Falank C, Bhattacharya B, Maung A, Seng S, Ratnasekera A, Bass G, Butler D, Pascual J, Srikureja D, Winicki N, Lynde J, Nowak B, Azar F, Thompson L, Nahmias J, Manasa M, Tesoriero R, Kumar S, Collom M, Kincaid M, Sperwer K, Santos A, Klune J, Turcotte J. To close or not to close? Wound management in emergent colorectal surgery, an EAST multicenter prospective cohort study. Journal Of Trauma And Acute Care Surgery 2024, 97: 73-81. PMID: 38523130, DOI: 10.1097/ta.0000000000004321.Peer-Reviewed Original ResearchSurgical site infectionLength of stayHospital length of stayWound classColorectal surgeryICU admissionProcedural detailsMulticenter prospective cohort studyTraumatic colorectal injuriesIn-hospital mortality rateAssociated with increased risk of mortalityAssociated with increased riskMortality rateRates of in-hospital mortalityEmergency colorectal surgeryColorectal surgery patientsProspective observational studyIn-hospital mortalityProspective cohort studyWound closure techniquesAverage length of stayRisk of mortalityStatistically significant differenceVasopressor therapyASA score
2023
Effects of novel Coronavirus (COVID-19) on presentation, management, and outcomes of acute cholecystitis at an academic tertiary care center cholecystitis management during COVID-19
Peters N, O'Connor R, Bhattacharya B, Kunstman J. Effects of novel Coronavirus (COVID-19) on presentation, management, and outcomes of acute cholecystitis at an academic tertiary care center cholecystitis management during COVID-19. Heliyon 2023, 9: e22043. PMID: 38027854, PMCID: PMC10658381, DOI: 10.1016/j.heliyon.2023.e22043.Peer-Reviewed Original ResearchTertiary care centerAcute cholecystitisCare centerPersonal protective equipment (PPE) guidelinesAcademic tertiary care centerAcute surgical problemsNon-operative managementPre-operative testingCOVID-19 pandemicNon-significant trendCholecystitis patientsComplication rateStudy cohortOperative managementControl cohortCOVID cohortSurgical problemsRetrospective analysisSurgical carePatientsControl groupEquipment guidelinesCholecystitisAspects of healthcareCohortDuration of antimicrobial treatment for complicated intra-abdominal infections after definitive source control: A systematic review, meta-analysis, and practice management guideline from the Eastern Association for the Surgery of Trauma
H. J, Rattan R, Patel N, Bhattacharya B, Butts C, Gupta S, Asfaw S, Como J, Sahr S, Bugaev N. Duration of antimicrobial treatment for complicated intra-abdominal infections after definitive source control: A systematic review, meta-analysis, and practice management guideline from the Eastern Association for the Surgery of Trauma. Journal Of Trauma And Acute Care Surgery 2023, 95: 603-612. PMID: 37316989, DOI: 10.1097/ta.0000000000003998.Peer-Reviewed Original ResearchConceptsComplicated intra-abdominal infectionsDefinitive source controlIntra-abdominal infectionsSurgery of TraumaAntimicrobial treatmentSystematic reviewAdult patientsLonger durationEastern AssociationDuration of antibioticsShorter antibiotic coursesPractice management guidelinesSurgical site infectionLevel of evidenceTerms of mortalitySource controlAntibiotic coursesRecurrent abscessesAntibiotic regimensHospital lengthRecommendations AssessmentSite infectionAntimicrobial durationLevel IIIMeta-AnalysisHypovolemic Shock
Jones T, Bhattacharya B, Davis K. Hypovolemic Shock. 2023, 137-146. DOI: 10.1007/978-3-031-22599-4_11.ChaptersAcute care surgeonsHypovolemic shockOptimal treatment strategyRecognition of complicationsCommon clinical scenariosOptimal clinical outcomesExcessive resuscitationGastrointestinal lossesSuch patientsClinical outcomesPostoperative phaseHemorrhagic shockSurgical interventionThird spacingTreatment strategiesDiagnostic modalitiesInfectious processClinical scenariosResuscitationPatientsSurgeonsComplicationsPathophysiologyEtiologyShockRoutine post-operative labs and healthcare system burden in acute appendicitis
Sznol J, Becher R, Maung A, Bhattacharya B, Davis K, Schuster K. Routine post-operative labs and healthcare system burden in acute appendicitis. The American Journal Of Surgery 2023, 226: 571-577. PMID: 37291012, DOI: 10.1016/j.amjsurg.2023.06.005.Peer-Reviewed Original ResearchConceptsHealthcare system burdenSystem burdenHealth care costsAppendicitis managementIncreased LOSUncomplicated AAAcute appendicitisRetrospective cohortClinical courseClinical variablesPatient populationMinimal comorbiditiesMultivariable modelingHealthcare costsCare costsPatientsLaboratory utilizationNational Health Expenditure AccountsLab utilizationLaboratory testingBurdenLaboratory testsAppendicitisComorbiditiesCohortAlcohol withdrawal syndrome in trauma patients: a study using the Trauma Quality Program Participant User File
Jones T, Bhattacharya B, Schuster K, Becher R, Kodadek L, Davis K, Maung A. Alcohol withdrawal syndrome in trauma patients: a study using the Trauma Quality Program Participant User File. Trauma Surgery & Acute Care Open 2023, 8: e001047. PMID: 37188153, PMCID: PMC10175962, DOI: 10.1136/tsaco-2022-001047.Peer-Reviewed Original ResearchAlcohol withdrawal syndromeAlcohol use disorderPositive blood alcohol concentrationHistory of AUDBlood alcohol concentrationParticipant User FileAdult patientsTrauma patientsWithdrawal syndromeAbbreviated Injury Scale headHigh-risk patient populationInjury scale headAdult trauma patientsPositive toxicology screenMultivariable logistic regressionRetrospective reviewRetrospective studyToxicology screenPatient populationTricyclic antidepressantsMAIN OUTCOMEAmerican CollegePatientsUse disordersUncommon occurrence
2022
Academic Medical Centers Experienced Higher Rates of Post-Operative Health-Care–Associated Infections during the COVID-19 Pandemic: A Post Hoc Analysis of an Eastern Association for the Surgery of Trauma Multicenter Trial
Tracy BM, Valdez CL, Crowley B, Seng S, Ratnasekera A, Collins CM, Bhattacharya B, O'Connor R, Sharp V, Gelbard RB. Academic Medical Centers Experienced Higher Rates of Post-Operative Health-Care–Associated Infections during the COVID-19 Pandemic: A Post Hoc Analysis of an Eastern Association for the Surgery of Trauma Multicenter Trial. Surgical Infections 2022, 23: 538-544. PMID: 35917388, DOI: 10.1089/sur.2022.148.Peer-Reviewed Original ResearchConceptsAcademic medical centerRisk factorsMedical CenterConcomitant COVID-19 infectionPost-operative healthTrauma multicenter trialIndependent risk factorSurgical site infectionInfection prevention effortsImportance of adherenceMulti-center studyCOVID-19 infectionCoronavirus disease 2019COVID-19 pandemicPost Hoc AnalysisHigh rateAppendicitis severityAcute appendicitisMulticenter trialPrimary outcomeSite infectionCommon HAIHoc AnalysisHospital typeDisease 2019Occult traumatic pneumothorax: Is routine follow up chest X-ray necessary?
Bhattacharya B, O'Connor R, Becher R, Schuster K, Davis K, Maung A. Occult traumatic pneumothorax: Is routine follow up chest X-ray necessary? Surgery In Practice And Science 2022, 9: 100073. DOI: 10.1016/j.sipas.2022.100073.Peer-Reviewed Original ResearchChest X-rayRoutine chest X-rayInjury Severity ScoreClinical managementInitial trauma evaluationUrban trauma centerComputerized tomography scanPaucity of evidenceOccult pneumothoracesPneumothorax progressionAdult patientsTrauma centerClinical evolutionClinical symptomsInjury scoreMean ageTrauma evaluationSeverity scoreTomography scanPatientsInterventionPneumothoracesSymptomsAgeX-ray
2021
Concerns Regarding Surgeon Special Interest and Years Following Termination of Training—Reply
Schuster KM, Bhattacharya B. Concerns Regarding Surgeon Special Interest and Years Following Termination of Training—Reply. JAMA Surgery 2021, 156: 1182-1183. PMID: 34347023, DOI: 10.1001/jamasurg.2021.3621.Peer-Reviewed Original ResearchOptimizing Cardiac Performance During the Perioperative Period
Jones T, Bhattacharya B, Davis K. Optimizing Cardiac Performance During the Perioperative Period. Current Geriatrics Reports 2021, 10: 175-181. DOI: 10.1007/s13670-021-00373-7.Peer-Reviewed Original ResearchAdverse cardiac eventsCardiac eventsPerioperative periodPre-existing ischemic heart diseasePerioperative adverse cardiac eventsPreoperative medical optimizationCardiac adverse eventsCardiac risk stratificationIschemic heart diseaseType of surgeryFurther prospective researchRandomized control trialCardiac optimizationPreoperative optimizationMedical comorbiditiesMedical optimizationNoncardiac surgeryAdverse eventsPatient ageHeart failureIntraoperative managementRisk stratificationSociety guidelinesHeart diseaseRisk factorsIncreased mortality with resuscitative endovascular balloon occlusion of the aorta only mitigated by strong unmeasured confounding: An expanded analysis using the National Trauma Data Bank
Linderman GC, Lin W, Becher RD, Maung AA, Bhattacharya B, Davis KA, Schuster KM. Increased mortality with resuscitative endovascular balloon occlusion of the aorta only mitigated by strong unmeasured confounding: An expanded analysis using the National Trauma Data Bank. Journal Of Trauma And Acute Care Surgery 2021, 91: 790-797. PMID: 33951027, PMCID: PMC8547242, DOI: 10.1097/ta.0000000000003265.Peer-Reviewed Original ResearchConceptsAcute kidney injuryResuscitative endovascular balloon occlusionLower extremity amputationEndovascular balloon occlusionBalloon occlusionExtremity amputationTraumatic injuryTreatment weightingREBOA placementNational Trauma Data BankInverse probabilityPlacement of REBOATrauma Data BankSevere traumatic injuryMortality effectsUnmeasured confoundersNoncompressible torso hemorrhagePotent confounderTQIP dataTQIP databaseAortic injuryKidney injuryRetrospective studyInjury patternsBaseline variablesImproved outcomes using laparoscopy for emergency colectomy after mitigating bias by negative control exposure analysis
Linderman GC, Lin W, Sanghvi MR, Becher RD, Maung AA, Bhattacharya B, Davis KA, Schuster KM. Improved outcomes using laparoscopy for emergency colectomy after mitigating bias by negative control exposure analysis. Surgery 2021, 171: 305-311. PMID: 34332782, DOI: 10.1016/j.surg.2021.06.048.Peer-Reviewed Original ResearchConceptsOpen surgeryEmergency colectomyNational Surgical Quality Improvement Program dataQuality Improvement Program dataPostoperative septic shockLow-risk patientsSurgical site infectionPatients meeting criteriaColorectal emergenciesElective colectomyUnderwent laparoscopyHospital stayOverall morbidityNationwide registryAnastomotic leakColectomy casesConverted groupSeptic shockSite infectionPatient selectionBaseline variablesImproved outcomesLaparoscopic surgeryTreatment weightingColectomyAnticoagulation Is Associated with Increased Mortality in Splenic Injuries
Bhattacharya B, Becher RD, Schuster KM, Davis KA, Maung AA. Anticoagulation Is Associated with Increased Mortality in Splenic Injuries. Journal Of Surgical Research 2021, 266: 1-5. PMID: 33975026, DOI: 10.1016/j.jss.2021.04.002.Peer-Reviewed Original ResearchConceptsNon-ACS patientsSplenic injuryAC patientsMultivariable binary logistic regressionIndependent risk factorEffect of anticoagulationInjury Severity ScoreUnits of RBCsBinary logistic regressionHospital courseMedian LOSIncreased MortalitySeverity scoreRisk factorsWorse outcomesAnticoagulationSplenic surgeryAC groupPatientsHigh mortalityInjuryLogistic regressionMortalitySerious injuriesAngiographyAssociation of Acute Care Surgeon Experience With Emergency Surgery Patient Outcomes and Mortality
Schuster KM, Hazelton JP, Rattigan D, Perez JM, Bhattacharya B. Association of Acute Care Surgeon Experience With Emergency Surgery Patient Outcomes and Mortality. JAMA Surgery 2021, 156: 472-478. PMID: 33688932, PMCID: PMC7948108, DOI: 10.1001/jamasurg.2021.0041.Peer-Reviewed Original ResearchMeSH KeywordsAcute Kidney InjuryAdultAgedBlood TransfusionClinical CompetenceEmergenciesFemaleHumansLength of StayMaleMiddle AgedPostoperative HemorrhagePostoperative PeriodReoperationRisk FactorsShock, SepticSurgeonsSurgical Wound InfectionSurvival RateTime FactorsTrauma CentersTreatment OutcomeUnited StatesWounds and InjuriesYoung AdultConceptsEmergency surgery outcomesEmergency Surgery ScoreMore septic shockEmergency surgical proceduresLength of staySurgeon experienceUnplanned returnOlder patientsSeptic shockSurgery scoreKidney failureSurgery outcomesOperating roomSurgical proceduresSurgeon groupAcademic level 1 trauma centerOrgan space surgical site infectionEmergency general surgical careLevel 1 trauma centerYears of experienceGeneral surgical interventionEmergency general surgeryAcute care surgeonsAcute kidney failureSurgical site infectionGeriatric Trauma Systems
Bhattacharya B, Davis K. Geriatric Trauma Systems. Current Trauma Reports 2021, 7: 8-14. DOI: 10.1007/s40719-020-00210-w.Peer-Reviewed Original Research
2020
The effect of anticoagulation on outcomes after liver and spleen injuries: A research consortium of New England centers for trauma (ReCONECT) study
Bhattacharya B, Askari R, Davis KA, Dorfman J, Eid AI, Elsharkawy AE, Kasotakis G, Mackey S, Odom S, Okafor BU, Rosenblatt M, Ruditsky A, Velmahos G, Maung AA. The effect of anticoagulation on outcomes after liver and spleen injuries: A research consortium of New England centers for trauma (ReCONECT) study. Injury 2020, 51: 1994-1998. PMID: 32482426, DOI: 10.1016/j.injury.2020.05.002.Peer-Reviewed Original ResearchConceptsNon-ACS patientsEffect of anticoagulationNon-operative managementSpleen injurySplenic injuryLiver injuryInitial non-operative managementSignificant differencesUse of anticoagulationBlood product transfusionMulticenter retrospective studyAC drugsMore PRBCsInjury gradeProduct transfusionCommon indicationAC patientsAtrial fibrillationRetrospective studyAnticoagulationSolid organsPatientsInjuryStudy periodLiverFluid and Electrolytes
Bhattacharya B, Maerz L. Fluid and Electrolytes. 2020, 17-35. DOI: 10.1007/978-3-030-39781-4_2.Peer-Reviewed Original ResearchFluid therapyResuscitative fluid therapySpecific surgical populationsMaintenance fluid therapyManagement of disordersCrystalloid-colloid debateSurgical populationSurgical patientsFluid resuscitationVolume control mechanismsTotal body waterSodium metabolismFluid managementBody fluid compartmentsPhysiologic principlesTherapyPhosphorus metabolismElectrolyte requirementsFluid compartmentsBody waterDisordersBaseline water
2019
Antimotility agents for the treatment of acute noninfectious diarrhea in critically ill patients: A practice management guideline from the Eastern Association for the Surgery of Trauma.
Bugaev N, Bhattacharya B, Chiu WC, Como JJ, Cripps MW, Ferrada P, Gelbard RB, Gondek S, Kasotakis G, Kim D, Mentzer C, Robinson BRH, Salcedo ES, Yeh DD. Antimotility agents for the treatment of acute noninfectious diarrhea in critically ill patients: A practice management guideline from the Eastern Association for the Surgery of Trauma. Journal Of Trauma And Acute Care Surgery 2019, 87: 915-921. PMID: 31574060, DOI: 10.1097/ta.0000000000002449.Peer-Reviewed Original ResearchConceptsDiphenoxylate/atropineNoninfectious diarrheaSurgery of TraumaElemental dietIll adultsIll patientsEastern AssociationIntensive care unit patientsResolution of diarrheaPractice management guidelinesCare unit patientsDaily clinical practiceLevel of evidenceDiarrhea resolutionFecal frequencyAntimotility agentsHospital lengthRecommendations AssessmentUnit patientsClinical diarrheaDiarrheaClinical practiceAtropineLevel IIIPatientsPromotility agents for the treatment of ileus in adult surgical patients: A practice management guideline from the Eastern Association for the Surgery of Trauma.
Bugaev N, Bhattacharya B, Chiu WC, Como JJ, Cripps MW, Ferrada P, Gelbard RB, Gondek S, Kasotakis G, Kim D, Mentzer C, Robinson BRH, Salcedo ES, Yeh DD. Promotility agents for the treatment of ileus in adult surgical patients: A practice management guideline from the Eastern Association for the Surgery of Trauma. Journal Of Trauma And Acute Care Surgery 2019, 87: 922-934. PMID: 31136527, DOI: 10.1097/ta.0000000000002381.Peer-Reviewed Original ResearchConceptsEarly enteral nutritionAdult surgical patientsResolution of ileusNormal bowel functionSurgery of TraumaSurgical patientsBowel functionHospital lengthEastern AssociationEffectiveness of metoclopramideEnteral feeding goalsEnteral nutrition goalsPractice management guidelinesEffect of metoclopramideTreatment of ileusMultiple medical interventionsDaily clinical practiceLevel of evidenceNeurohormonal dysfunctionEnteral nutritionPromotility agentsRecommendations AssessmentExogenous opioidsFluid overloadSupportive care