Functional and Physical Interaction Between the Mismatch Repair and the FA-BRCA Pathways.
Williams S, Wilson J, Clark A, Mitson-Salazar A, Bale A, Jones N, Kupfer G. Functional and Physical Interaction Between the Mismatch Repair and the FA-BRCA Pathways. Blood 2010, 116: 3370. DOI: 10.1182/blood.v116.21.3370.3370.Peer-Reviewed Original ResearchFA-BRCA pathwayFA cell linesFANCD2 foci formationFanconi anemiaFA proteinsMMR pathwayRepair proteinsCell linesInterstrand crosslinksFoci formationMonoubiquitylation of FANCD2Mismatch repairMismatch repair proteinsFA pathway activationMismatch repair factorsColon carcinoma cell line HCT116DNA interstrand crosslinksMsh2-deficient cellsPossible functional overlapHuman colon carcinoma cell line HCT116Plasmid-based assayChromosome breakage analysisChromatin localizationChromatin loadingRNAi flies