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DESCRIPTION:Danielle Miyagishima\, PhD\, conducted her doctoral research i
 n Dr. Murat Günel’s lab\, focusing on a comprehensive cellular and molecu
 lar examination of meningiomas. Her work uncovered spatial compartmentali
 zation within meningiomas\, identifies predominant signaling pathways act
 ive in meningiomas\, and reveals complex hormonal regulation within the t
 umor microenvironment. Miyagishima was a recipient of the 2024 Carolyn Sl
 ayman Prize in Genetics which recognizes students for remarkable scientif
 ic achievements and exceptional contributions to the scientific community
 . She is also the co-founder of the Yale Cushing Society\, whose mission 
 is to foster a direct educational and research interface between Yale und
 ergraduates and medical students and neurosurgery residents and faculty. 
 Hosted by:Murat Günel\, MD Yale Zoom You are invited to a scheduled Zoom 
 meeting. Zoom is Yale’s audio and visual conferencing platform. Topic: Cl
 inical Neuroscience Grand Rounds Department of NeurosurgeryJoin from PC\,
  Mac\, Linux\, iOS or Android:https://yale.zoom.us/j/97433924693?pwd=hCC9
 37EJ6Xa5m4oeTUliVGmcNTbVZJ.1 Password: 638836 Or Telephone：203-432-9666 (
 2-ZOOM if on-campus) or 646 568 7788 Meeting ID: 974 3392 4693 Internatio
 nal numbers available:https://yale.zoom.us/u/aqc2vnhkp Program Objective(
 s):1 Understand meningioma as a spatially organized ecosystem and identif
 y how discrete tumor\, immune\, and stromal niches—rather than homogeneou
 s cell masses—drive clinical progression and immune evasion.2 Relate path
 ognomonic morphology (such as meningothelial whorls and lobules) to molec
 ular aggressiveness by connecting these features to spatially constrained
  hypoxic niches with EMT-like and proliferative programs that predict gra
 de and recurrence.3 Evaluate AI-based molecular inference in clinical pra
 ctice by assessing the utility of hybrid deep learning models (e.g.\, Men
 ingNet) to predict aggressive molecular states directly from standard H&E
  slides for institution-agnostic risk stratification. CME Language Accred
 itation Statement:Yale School of Medicine is accredited by the Accreditat
 ion Council for Continuing Medical Education (ACCME) to provide continuin
 g medical education for physicians. Designation Statement:Yale School of 
 Medicine designates this Live Activity for a maximum of 1.00 AMA PRA Cate
 gory 1 Credit(s)™ . Physicians should only claim credit commensurate with
  the extent of their participation in the activity. Disclosure Policy:It 
 is the policy of Yale School of Medicine\, Continuing Medical Education (
 CME)\, to ensure balance\, independence\, objectivity\, and scientific ri
 gor in all its educational programs. All individuals involved in the deve
 lopment and presentation of Accredited Continuing Education activities ar
 e required to disclose all financial relationship(s) with ineligible comp
 anies (those whose primary business is producing\, marketing\, selling\, 
 re-selling\, or distributing healthcare products used by or on patients) 
 that has occurred within the past 24 months\; and the opportunity to affe
 ct the content of CME about the products or services of the commercial in
 terests. This information is disclosed to all activity participants prior
  to the commencement of the educational activity. Mitigation of Financial
  Relationships Statement:Yale CME adheres to the ACCME’s Standards for In
 tegrity and Independence in Accredited Continuing Education. Any individu
 als in a position to control the content of a CE activity\, including fac
 ulty\, planners\, reviewers or others are required to disclose all releva
 nt financial relationships with ineligible companies. All relevant confli
 cts of interest have been mitigated prior to the commencement of the acti
 vity.\n\nSpeaker:\nDanielle Miyagishima\n\nAdmission:\nFree\n\nDetails UR
 L:\nhttps://medicine.yale.edu/event/clinical-neuroscience-grand-rounds-ma
 y-7-2026/\n
DTEND;TZID=America/New_York:20260507T180000
DTSTAMP:20260506T160555Z
DTSTART;TZID=America/New_York:20260507T170000
LOCATION:Zoom\nPassword: 638836\, URL: https://yale.zoom.us/j/97433924693?
 pwd=hCC937EJ6Xa5m4oeTUliVGmcNTbVZJ.1
SEQUENCE:0
STATUS:Confirmed
SUMMARY:Clinical Neuroscience Grand Rounds
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