COVID-19 Virus Increases Risk for Other Infections by Disrupting Normal Mix of Gut Bacteria
Infection with the pandemic virus, SARS-CoV-2, can reduce the number of bacterial species in a patient’s gut, with the lesser diversity creating space for dangerous microbes to thrive, a new study finds.Source: NYU Langone Health
Will Long COVID Research Provide Answers for Poorly Understood Diseases Like ME/CFS?
ME/CFS (myalgic encephalomyelitis/chronic fatigue syndrome) is a highly disabling, severe condition that has been largely overlooked and even questioned as an illness by physicians and biomedical researchers for decades. But now, scientists including Yale's Akiko Iwasaki and Harlan Krumholz are finding parallels between post-infection long COVID and ME/CFS.
New Findings on Endometrial Cancer Treated With Pembrolizumab
New research from Yale Cancer Center reveals for the first time ever a differential clinical response to pembrolizumab in Lynch-like (mutated) vs methylated microsatellite instability-high (MSI-H) uterine cancer patients, increasing our understanding about the proportion of patients that derive benefit from immune checkpoint blockade.
‘Prime and Spike’ Nasal Vaccine Strategy Helps Combat COVID
The new “prime” and “spike” approach may help prevent breakthrough infections of vaccinated individuals by bolstering immune response within the mucosal lining of the respiratory tract, which are the first cells attacked by COVID-19.Source: YaleNews
Chemical Hair Straighteners and Cancer: What You Need to Know
If you are a woman who has used chemical hair straightening products, a new report issued by the National Institutes of Health may have caused you concern. The NIH released findings that link chemical hair straightening products to uterine cancer. These results might cause you to question your own use of hair care products and wonder what you should do next. For now, experts suggest that there is no need to panic. More research is needed before we know for sure which ingredients may be problematic. But still, women of color and others who use these products are (reasonably) worried. We talked to both medical and hair care experts to get some answers to ease your mind.Source: Health & Wellness
New Mouse Model Provides Unprecedented Look at Human Immune System
Despite the critical role of neutrophils in the human immune system, no one has been able to study them in a living context, limiting investigations of their properties. But now, a team of Yale researchers has developed the first humanized mouse model that will permit research on neutrophils in vivo.
Keith Choate, MD ’04, PhD ’01, Appointed Chair/Chief of Dermatology
Keith Choate, MD, PhD, will become chair of the Department of Dermatology and chief of Dermatology of Yale New Haven Hospital effective October 1, 2022. Choate will also work collaboratively with delivery network leadership to advance dermatological services across Yale New Haven Health System.
Leffell Prize Presented to Michael Caty, MD
The annual Leffell Prize was established by David J. Leffell, MD, and Cindy Leffell in 2008 to recognize the medical school faculty member who best exemplifies clinical expertise, a commitment to teaching, and the highest standards of care and compassion for patients.
Microneedling Can Help Surgical Scars Fade, Especially If Done Early
A technique called microneedling may help surgical scars heal more attractively — especially if it's done within a couple of months of surgery, a small study suggests. Researchers found that for 25 patients, microneedling improved the long-term appearance of scars after various types of surgery — based on both patient and doctor ratings. But the sooner it was done, the better. Patients who underwent their first microneedling session within six or seven weeks of surgery had the best results. That, the researchers said, goes against the "conventional wisdom," which holds that microneedling should be delayed until scars are about a year old.Source: U.S. News
Marie Robert, MD, Jordan Pober, MD, PhD, Awarded POINTS Grant to Study Pathogenesis of Celiac Disease
Marie Robert, MD, Professor of Pathology and of Medicine (Digestive Diseases), and Jordan Pober, MD, PhD, the Bayer Professor of Translational Medicine and Professor of Immunobiology, Pathology, and Dermatology, have been awarded a grant from the Program for the Promotion of Interdisciplinary Team Science (POINTS) at Yale School of Medicine to study the Pathogenesis of Celiac Disease.
Yale Cancer Center Researchers Awarded Grants by Breast Cancer Research Foundation
The Breast Cancer Research Foundation (BCRF) Scientific Advisory Board and its Board of Directors recently announced its 2022 research grants, including six funded grants at Yale Cancer Center and Smilow Cancer Hospital awarded to Mehra Golshan, MD, MBA, Melinda Irwin, PhD, MPH, Ian Krop, MD, PhD, Lajos Pusztai, MD, DPhil, David Rimm, MD, PhD, and Eric Winer, MD to support their research.
Calorie Reduction Lowers Protein Linked to the Aging Process
In a new study, Yale researchers show that moderate calorie restriction in people reduces the production of a protein called SPARC, which then reins in harmful inflammation and improves health in the aged. It could be a target for extending human health span, they report.