2014
Integrin-driven monocyte to dendritic cell conversion in modified extracorporeal photochemotherapy
Gonzalez AL, Berger CL, Remington J, Girardi M, Tigelaar RE, Edelson RL. Integrin-driven monocyte to dendritic cell conversion in modified extracorporeal photochemotherapy. Clinical & Experimental Immunology 2014, 175: 449-457. PMID: 24188174, PMCID: PMC3927905, DOI: 10.1111/cei.12231.Peer-Reviewed Original ResearchConceptsCutaneous T-cell lymphomaDC differentiationHuman leucocyte antigen DDendritic antigen-presenting cellsPlasma proteinsAntigen-presenting cellsT-cell lymphomaECP efficacyHost diseaseClinical efficacySafety profileSelective immunizationCell lymphomaAntigen DCell treatmentMonocytesPhenotypic expressionEfficacyNovel mechanismECPDifferentiationCD83ImmunosuppressionCD86Fibronectin
2013
Induction of monocyte-to-dendritic cell maturation by extracorporeal photochemotherapy: Initiation via direct platelet signaling
Durazzo TS, Tigelaar RE, Filler R, Hayday A, Girardi M, Edelson RL. Induction of monocyte-to-dendritic cell maturation by extracorporeal photochemotherapy: Initiation via direct platelet signaling. Transfusion And Apheresis Science 2013, 50: 370-378. PMID: 24360371, PMCID: PMC4167725, DOI: 10.1016/j.transci.2013.11.008.Peer-Reviewed Original ResearchConceptsCutaneous T-cell lymphomaExtracorporeal photochemotherapyDendritic cellsDendritic cell maturationT-cell lymphomaInduction of monocytesEvidence of inductionPost-capillary venulesDC maturationCell lymphomaClinical actionsCell maturationPlatelet signalingMonocytesPhotochemotherapyReceptor-ligand interactionsNovel mechanismInductionPhysiological inductionMaturationPrevious studiesLymphomaTherapyVenules
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