Keith Choate, MD, PhD

Professor of Dermatology, Pathology, and Genetics; Director of Research, Dermatology

Physician Biography

Dr. Choate grew up in Connecticut and California and attended Caterbury School and Stanford University where he graduated in 3 years with honors in biological sciences in 1995. As a researcher in Paul Khavari's laboratory, he performed the first successful ex vivo gene therapy for the genetic skin disorder lamellar ichthyosis and came to Yale in 1996 to begin the Medical Scientist Training Program. He received the M.Phil ('00), Ph.D. (Cell Biology, '01), and MD ('04, cum laude) before an internship at Yale-New Haven Hospital in Internal Medicine and residency in Dermatology. He pursued post-doctoral training in human genetics. Dr. Choate has published over 30 peer-reviewed articles in Science, Nature, Human Molecular Genetics, The American Journal of Human Genetics, The Journal of Clinical Investigation, Nature Medicine, and the Journal of the American Academy of Dermatology. He serves on committees for the Society for Pediatric Dermatology, the Pediatric Dermatolgy Research Alliance, the Society for Investigative Dermatology, the Yale Medical Scientist Training Program, and the American Board of Dermatology. His research is funded by the National Institutes of Health and the Foundation for Ichthyosis and Related Skin Types. Dr. Choate's laboratory is dedicated to understading fundamental genetic and biologic pathways relevant to human disease.

Clinical Interests

  • Acne Vulgaris
  • Dermatitis, Atopic
  • Dermatology
  • Genetics
  • Ichthyosis
  • Keratoderma, Palmoplantar
  • Mosaicism
  • Pemphigoid, Bullous
  • Pemphigus
  • Psoriasis
  • Skin Diseases
  • Skin Neoplasms
  • High-Throughput Nucleotide Sequencing

Patient Care

Accepts new patients? Yes
Patient Type: Adult; Adolescent; Child; Geriatric
Referrals: MD to MD Consult

Patient Care Organizations

Dermatology: Medical Dermatology: Yale Dermatology Associates



Yale Cancer Center

Yale Medicine

Office of Cooperative Research

Clinical Trials

Conditions Study Title
Immune System RESET Trial - Part 1 (Followed by Reset Trial - Part 2) - A Phase 3 Trial in Subjects With Sjögren-Larsson Syndrome (SLS)
Children's Health, Diseases of the Integumentary System, Genetics - Pediatric Prospective Evaluation of Infants and Children With Congenital Ichthyosis

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Contact Info

Keith Choate, MD, PhD
Patient Care Location
Yale Dermatology AssociatesDoctors Building
2 Church Street South, Ste 305

New Haven, CT 06519
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Mailing Address
DermatologyPO Box 208059
333 Cedar Street

New Haven, CT 06520-8059

Curriculum Vitae