2015
Hospital variation in admission to intensive care units for patients with acute myocardial infarction
Chen R, Strait KM, Dharmarajan K, Li SX, Ranasinghe I, Martin J, Fazel R, Masoudi FA, Cooke CR, Nallamothu BK, Krumholz HM. Hospital variation in admission to intensive care units for patients with acute myocardial infarction. American Heart Journal 2015, 170: 1161-1169. PMID: 26678638, PMCID: PMC5459386, DOI: 10.1016/j.ahj.2015.09.003.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAnterior Wall Myocardial InfarctionCoronary Care UnitsHealth Care RationingHospital MortalityHumansLength of StayMaleMiddle AgedOutcome and Process Assessment, Health CarePatient AdmissionQuality ImprovementRetrospective StudiesRisk AssessmentTriageUnited StatesConceptsAcute myocardial infarctionIntensive care unitCritical care therapiesRisk-standardized mortality ratesHospital risk-standardized mortality ratesICU admissionResource-intensive settingsCare therapyAMI patientsCare unitMyocardial infarctionMortality rateAdult hospitalizationsHospital variationNinth RevisionClinical ModificationICU triageInternational ClassificationBetter outcomesPatientsHospitalAdmissionPremier databaseTherapyAppropriate use
2008
A Campaign to Improve the Timeliness of Primary Percutaneous Coronary Intervention Door-to-Balloon: An Alliance for Quality
Krumholz HM, Bradley EH, Nallamothu BK, Ting HH, Batchelor WB, Kline-Rogers E, Stern AF, Byrd JR, Brush JE. A Campaign to Improve the Timeliness of Primary Percutaneous Coronary Intervention Door-to-Balloon: An Alliance for Quality. JACC Cardiovascular Interventions 2008, 1: 97-104. PMID: 19393152, DOI: 10.1016/j.jcin.2007.10.006.Peer-Reviewed Original ResearchMeSH KeywordsAngioplasty, Balloon, CoronaryCoronary Care UnitsFollow-Up StudiesHumansInpatientsMyocardial InfarctionQuality Assurance, Health CareTime FactorsConceptsST-segment elevation myocardial infarctionD2B timeD2B AllianceCatheterization laboratoryPrimary percutaneous coronary interventionEmergency medical services personnelElevation myocardial infarctionMajority of patientsPercutaneous coronary interventionNon-transferred patientsAmerican Heart AssociationMedical services personnelEmergency medicine physiciansPre-hospital electrocardiogramTeam-based approachCoronary interventionHospital arrivalHeart AssociationMyocardial infarctionAmerican CollegeMedicine physiciansLikelihood of survivalPatientsUnderused strategyBalloon
2007
Ischaemic symptoms, quality of care and mortality during myocardial infarction
Schelbert EB, Rumsfeld JS, Krumholz HM, Canto JG, Magid DJ, Masoudi FA, Reid KJ, Spertus JA. Ischaemic symptoms, quality of care and mortality during myocardial infarction. Heart 2007, 94: e2. PMID: 17639097, PMCID: PMC3703470, DOI: 10.1136/hrt.2006.111674.Peer-Reviewed Original ResearchConceptsIschemic symptomsMyocardial infarctionQuality of careST-elevation myocardial infarctionACE/ARBNon-cardiac comorbiditiesPositive cardiac enzymesEvidence of infarctionHospital mortalityCessation counsellingHospital survivalReperfusion therapyCardiac enzymesConsecutive patientsMI careMI symptomsCare indicatorsPatient reportsSymptom recognitionChart documentationPatientsUS hospitalsSymptomsInfarctionCare
2004
ACC/AHA Guidelines for the Management of Patients With ST-Elevation Myocardial Infarction—Executive Summary
Antman EM, Anbe DT, Armstrong PW, Bates ER, Green LA, Hand M, Hochman JS, Krumholz HM, Kushner FG, Lamas GA, Mullany CJ, Ornato JP, Pearle DL, Sloan MA, Smith SC, Antman E, Smith S, Alpert J, Anderson J, Faxon D, Fuster V, Gibbons R, Gregoratos G, Halperin J, Hiratzka L, Hunt S, Jacobs A, Ornato J. ACC/AHA Guidelines for the Management of Patients With ST-Elevation Myocardial Infarction—Executive Summary. Circulation 2004, 110: 588-636. PMID: 15289388, DOI: 10.1161/01.cir.0000134791.68010.fa.Peer-Reviewed Original ResearchAdultAge FactorsAgedAmerican Heart AssociationAngioplasty, Balloon, CoronaryCardiovascular AgentsCombined Modality TherapyContraindicationsCoronary AngiographyCoronary Artery BypassCoronary Care UnitsDecision TreesDiagnosis, DifferentialEarly DiagnosisElectrocardiographyEmergency Medical ServicesEmergency Service, HospitalFemaleGuideline AdherenceHeart ArrestHeart Conduction SystemHumansMaleMiddle AgedMyocardial InfarctionOutcome Assessment, Health CarePatient DischargePatient Education as TopicPatient SelectionRisk AssessmentRisk FactorsSeverity of Illness IndexSex FactorsSurvival AnalysisThrombolytic TherapyUnited StatesACC/AHA Guidelines for the Management of Patients With ST-Elevation Myocardial Infarction—Executive Summary A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 1999 Guidelines for the Management of Patients With Acute Myocardial Infarction)
Antman EM, Anbe DT, Armstrong PW, Bates ER, Green LA, Hand M, Hochman JS, Krumholz HM, Kushner FG, Lamas GA, Mullany CJ, Ornato JP, Pearle DL, Sloan MA, Smith SC, Antman E, Smith S, Alpert J, Anderson J, Faxon D, Fuster V, Gibbons R, Gregoratos G, Halperin J, Hiratzka L, Hunt S, Jacobs A, Ornato J. ACC/AHA Guidelines for the Management of Patients With ST-Elevation Myocardial Infarction—Executive Summary A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 1999 Guidelines for the Management of Patients With Acute Myocardial Infarction). Journal Of The American College Of Cardiology 2004, 44: 671-719. PMID: 15358045, DOI: 10.1016/j.jacc.2004.07.002.Peer-Reviewed Original ResearchMeSH KeywordsAngioplasty, Balloon, CoronaryCardiovascular AgentsContraindicationsCoronary AngiographyCoronary Artery BypassCoronary Care UnitsDecision TreesDiagnosis, DifferentialEarly DiagnosisEmergency Medical ServicesEmergency Service, HospitalHeart ArrestHeart Conduction SystemHumansMyocardial InfarctionOutcome Assessment, Health CarePatient DischargePatient Education as TopicRisk AssessmentRisk FactorsSeverity of Illness IndexThrombolytic Therapy
2003
Effects of age on the quality of care provided to older patients with acute myocardial infarction
Rathore SS, Mehta RH, Wang Y, Radford MJ, Krumholz HM. Effects of age on the quality of care provided to older patients with acute myocardial infarction. The American Journal Of Medicine 2003, 114: 307-315. PMID: 12681459, DOI: 10.1016/s0002-9343(02)01531-0.Peer-Reviewed Original ResearchMeSH KeywordsAdrenergic beta-AntagonistsAge FactorsAgedAged, 80 and overAttitude of Health PersonnelCohort StudiesCombined Modality TherapyCoronary Care UnitsCritical CareDrug UtilizationFemaleGuideline AdherenceHealth Services AccessibilityHealth Services for the AgedHumansLogistic ModelsMaleMedicareMyocardial InfarctionOdds RatioPractice Patterns, Physicians'Quality of Health CareRisk AssessmentSurvival AnalysisThrombolytic TherapyUnited StatesConceptsAcute reperfusion therapyAcute myocardial infarctionMyocardial infarctionReperfusion therapyEffect of ageElderly patientsOlder patientsAge-associated variationsGuideline-recommended medical therapyAngiotensin-converting enzyme inhibitorGuideline-indicated therapiesPrescription of aspirinUse of aspirinCooperative Cardiovascular ProjectUse of therapiesQuality of careAcute reperfusionTreatment contraindicationsMedical therapyComorbid conditionsACE inhibitorsMedicare patientsHospital effectsPatientsEnzyme inhibitors
2002
Cardiogenic shock complicating acute myocardial infarction in elderly patients: Does admission to a tertiary center improve survival?
Berger AK, Radford MJ, Krumholz HM. Cardiogenic shock complicating acute myocardial infarction in elderly patients: Does admission to a tertiary center improve survival? American Heart Journal 2002, 143: 768-776. PMID: 12040336, DOI: 10.1067/mhj.2002.122289.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionCardiogenic shockMyocardial infarctionRevascularization servicesCoronary revascularizationPrognosis of patientsCommunity-based cohortCooperative Cardiovascular Project databaseCardiovascular resourcesEarly revascularizationIndex hospitalizationClinical characteristicsElderly patientsCoronary angioplastyTertiary centerBetter prognosisRevascularization capabilityInvasive strategyClinical trialsTreatment strategiesSurgery facilitiesInfarctionPatientsHospitalEarly benefits
1999
Gender differences in symptom presentation associated with coronary heart disease
Milner K, Funk M, Richards S, Wilmes R, Vaccarino V, Krumholz H. Gender differences in symptom presentation associated with coronary heart disease. The American Journal Of Cardiology 1999, 84: 396-399. PMID: 10468075, DOI: 10.1016/s0002-9149(99)00322-7.Peer-Reviewed Original ResearchConceptsCoronary heart diseaseNon-chest pain symptomsChest painEmergency departmentPain symptomsUnadjusted analysesHeart diseaseSymptom presentationYale-New Haven HospitalSubgroup of patientsNurse data collectorsGender differencesMidback painProspective studyPainNauseaVomitingSymptomsPatientsWomenDyspneaSignificant gender differencesMenDiseaseIndigestion