2022
Trends in Adverse Event Rates in Hospitalized Patients, 2010-2019
Eldridge N, Wang Y, Metersky M, Eckenrode S, Mathew J, Sonnenfeld N, Perdue-Puli J, Hunt D, Brady PJ, McGann P, Grace E, Rodrick D, Drye E, Krumholz HM. Trends in Adverse Event Rates in Hospitalized Patients, 2010-2019. JAMA 2022, 328: 173-183. PMID: 35819424, PMCID: PMC9277501, DOI: 10.1001/jama.2022.9600.Peer-Reviewed Original ResearchMeSH KeywordsAccidental FallsAdultAgedAged, 80 and overCross InfectionCross-Sectional StudiesDrug-Related Side Effects and Adverse ReactionsFemaleHeart FailureHospitalizationHumansMaleMedicareMiddle AgedMyocardial InfarctionPatient SafetyPneumoniaPostoperative ComplicationsPressure UlcerRisk AssessmentSurgical Procedures, OperativeUnited StatesConceptsMajor surgical proceduresAcute myocardial infarctionAdverse event ratesGeneral adverse eventsAdverse eventsHeart failureAdverse drug eventsAcute care hospitalsMyocardial infarctionHospital-acquired infectionsSurgical proceduresEvent ratesHospital dischargeCare hospitalDrug eventsMedicare Patient Safety Monitoring SystemSerial cross-sectional studyPatient safetyUS acute care hospitalsHospital adverse eventsSignificant decreaseSurgical procedure groupsCross-sectional studyRisk-adjusted ratesAdult patients
2015
Association of hospital volume with readmission rates: a retrospective cross-sectional study
Horwitz LI, Lin Z, Herrin J, Bernheim S, Drye EE, Krumholz HM, Hines HJ, Ross JS. Association of hospital volume with readmission rates: a retrospective cross-sectional study. The BMJ 2015, 350: h447. PMID: 25665806, PMCID: PMC4353286, DOI: 10.1136/bmj.h447.Peer-Reviewed Original ResearchConceptsReadmission ratesHospital volumeRetrospective cross-sectional studyUS acute care hospitalsHospital readmission ratesAcute care hospitalsCross-sectional studyMedical cancer treatmentCare hospitalAdult dischargesHospital characteristicsMedicare feeCancer treatmentHospitalAssociationDaysService dataPatientsCardiovascularGynecologyQuintileNeurology
2013
Income inequality and 30 day outcomes after acute myocardial infarction, heart failure, and pneumonia: retrospective cohort study
Lindenauer PK, Lagu T, Rothberg MB, Avrunin J, Pekow PS, Wang Y, Krumholz HM. Income inequality and 30 day outcomes after acute myocardial infarction, heart failure, and pneumonia: retrospective cohort study. The BMJ 2013, 346: f521. PMID: 23412830, PMCID: PMC3573180, DOI: 10.1136/bmj.f521.Peer-Reviewed Original ResearchConceptsIncome inequalityAcute myocardial infarctionUS statesRetrospective cohort studyDay of admissionHeart failureMyocardial infarctionCohort studyInequality levelsIndividual incomeGini coefficientUS acute care hospitalsHighest quarterDays of dischargeDays of hospitalizationRisk of readmissionRisk of deathPatient socioeconomic characteristicsRisk of mortalityAcute care hospitalsSocioeconomic characteristicsInequalityLogistic regression modelsCare hospitalReadmission analysis
2010
Is Same-Hospital Readmission Rate a Good Surrogate for All-Hospital Readmission Rate?
Nasir K, Lin Z, Bueno H, Normand SL, Drye EE, Keenan PS, Krumholz HM. Is Same-Hospital Readmission Rate a Good Surrogate for All-Hospital Readmission Rate? Medical Care 2010, 48: 477-481. PMID: 20393366, DOI: 10.1097/mlr.0b013e3181d5fb24.Peer-Reviewed Original ResearchConceptsRisk-standardized readmission ratesHospital readmission ratesSame-hospital readmissionsSame-hospital readmission ratesDays of dischargeReadmission ratesHeart failureUS acute care hospitalsThirty-day readmissionStandard Analytic FilesAcute care hospitalsHierarchical logistic regression modelsLogistic regression modelsCause readmissionHF readmissionIndex hospitalizationCare hospitalHospital readmissionAnalytic FilesMedicare inpatientReadmissionStudy populationHospital measuresReadmission measuresHospitalization
2009
Recent National Trends in Readmission Rates After Heart Failure Hospitalization
Ross JS, Chen J, Lin Z, Bueno H, Curtis JP, Keenan PS, Normand SL, Schreiner G, Spertus JA, Vidán MT, Wang Y, Wang Y, Krumholz HM. Recent National Trends in Readmission Rates After Heart Failure Hospitalization. Circulation Heart Failure 2009, 3: 97-103. PMID: 19903931, PMCID: PMC2830811, DOI: 10.1161/circheartfailure.109.885210.Peer-Reviewed Original ResearchConceptsCause readmission rateReadmission ratesHeart failureRecent national trendsHospital variationService beneficiariesAcute-care nonfederal hospitalsUS acute care hospitalsHeart failure hospitalizationHospital readmission ratesAcute care hospitalsNational trendsNational Quality ForumMedicare administrative dataDistinct hospitalizationsFailure hospitalizationMultiple comorbiditiesCare hospitalNonfederal hospitalsMedicare beneficiariesHospitalizationHospitalQuality ForumStudy periodAdministrative data
2008
Mental Disorders, Quality of Care, and Outcomes Among Older Patients Hospitalized With Heart Failure: An Analysis of the National Heart Failure Project
Rathore SS, Wang Y, Druss BG, Masoudi FA, Krumholz HM. Mental Disorders, Quality of Care, and Outcomes Among Older Patients Hospitalized With Heart Failure: An Analysis of the National Heart Failure Project. JAMA Psychiatry 2008, 65: 1402-1408. PMID: 19047527, PMCID: PMC2790277, DOI: 10.1001/archpsyc.65.12.1402.Peer-Reviewed Original ResearchConceptsMental illness diagnosisACE inhibitor prescriptionHeart failureMultivariate adjustmentQuality of careIllness diagnosisInhibitor prescriptionLVEF evaluationMental illnessNational Heart Failure ProjectAngiotensin-converting enzyme inhibitorVentricular ejection fraction assessmentUS acute care hospitalsLeft ventricular ejection fraction assessmentHeart Failure ProjectAcute care hospitalsHigher crude ratesEjection fraction assessmentPopulation-based sampleEligible patientsTreatment contraindicationsCause readmissionElderly patientsOlder patientsCare hospital
2007
Certificate of Need Regulation and Cardiac Catheterization Appropriateness After Acute Myocardial Infarction
Ross JS, Ho V, Wang Y, Cha SS, Epstein AJ, Masoudi FA, Nallamothu BK, Krumholz HM. Certificate of Need Regulation and Cardiac Catheterization Appropriateness After Acute Myocardial Infarction. Circulation 2007, 115: 1012-1019. PMID: 17283258, DOI: 10.1161/circulationaha.106.658377.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionMyocardial infarctionCardiac catheterizationHospital coronary artery bypass graft surgeryCoronary artery bypass graft surgeryArtery bypass graft surgeryLower ratesUS acute care hospitalsCardiac catheterization capabilitiesChart-abstracted dataBypass graft surgeryDay of admissionAcute care hospitalsComplex medical careQuality of careGraft surgeryCatheterization ratesClinical characteristicsCON regulationsHospital characteristicsMedicare patientsRetrospective analysisCatheterizationHealthcare costsFull cohort
2002
Evaluation of a Consumer-Oriented Internet Health Care Report Card: The Risk of Quality Ratings Based on Mortality Data
Krumholz HM, Rathore SS, Chen J, Wang Y, Radford MJ. Evaluation of a Consumer-Oriented Internet Health Care Report Card: The Risk of Quality Ratings Based on Mortality Data. JAMA 2002, 287: 1277-1287. PMID: 11886319, DOI: 10.1001/jama.287.10.1277.Peer-Reviewed Original ResearchConceptsProcess of careMortality rateHospital ratingEnzyme inhibitorsUS acute care hospitalsSystematic medical record reviewIndividual hospitalsStudy periodAcute myocardial infarction mortalityAcute reperfusion therapyReperfusion therapy ratesMedical record reviewService beneficiaries 65 yearsCooperative Cardiovascular ProjectBeneficiaries 65 yearsAcute care hospitalsMyocardial infarction mortalityHealth care report cardsQuality of careCare report cardsHospital performanceReperfusion therapyTherapy ratesCare hospitalRecord review
2001
Sex Differences in Cardiac Catheterization: The Role of Physician Gender
Rathore SS, Chen J, Wang Y, Radford MJ, Vaccarino V, Krumholz HM. Sex Differences in Cardiac Catheterization: The Role of Physician Gender. JAMA 2001, 286: 2849-2856. PMID: 11735761, DOI: 10.1001/jama.286.22.2849.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionCardiac catheterizationMale physiciansFemale physiciansPatient sexPhysician sexCardiac proceduresRetrospective medical record reviewSex differencesUS acute care hospitalsProcedure useCardiac procedure useDay of admissionMedical record reviewCooperative Cardiovascular ProjectAcute care hospitalsCare hospitalMultivariable analysisRecord reviewPotential confoundersMyocardial infarctionPhysician genderCatheterizationMAIN OUTCOMEClinical care