2008
Systolic Function as a Predictor of Mortality and Quality of Life in Long‐term Survivors with Heart Failure
McNamara R, Austin B, Wang Y, Smith G, Vaccarine V, Krumholz H. Systolic Function as a Predictor of Mortality and Quality of Life in Long‐term Survivors with Heart Failure. Clinical Cardiology 2008, 31: 119-124. PMID: 18383045, PMCID: PMC6653267, DOI: 10.1002/clc.20118.Peer-Reviewed Original ResearchConceptsQuality of lifeEjection fractionHeart failureLong-term survivorsFunctional declineSystolic functionKansas City Cardiomyopathy Questionnaire scoreModest survival advantageReduced ejection fractionDaily living scoreDisease-related qualityPredictors of mortalityHeart failure patientsClinical summary scoreLong-term survivalHigh mortality rateKCCQ scoresRenal insufficiencyFailure patientsLiving scoreDiabetes mellitusOverall mortalityPrimary outcomeLimitation scoresQOL scores
2003
Outcomes in heart failure patients with preserved ejection fraction mortality, readmission and functional decline
Smith G, Masoudi F, Vaccarino V, Radford M, Krumholz H. Outcomes in heart failure patients with preserved ejection fraction mortality, readmission and functional decline. ACC Current Journal Review 2003, 12: 61. DOI: 10.1016/s1062-1458(03)00300-3.Peer-Reviewed Original ResearchOutcomes in heart failure patients with preserved ejection fraction Mortality, readmission, and functional decline
Smith GL, Masoudi FA, Vaccarino V, Radford MJ, Krumholz HM. Outcomes in heart failure patients with preserved ejection fraction Mortality, readmission, and functional decline. Journal Of The American College Of Cardiology 2003, 41: 1510-1518. PMID: 12742291, DOI: 10.1016/s0735-1097(03)00185-2.Peer-Reviewed Original ResearchConceptsDepressed ejection fractionRisk of readmissionEjection fractionHeart failureFunctional declineHeart failure patientsHF patientsFailure patientsHospital dischargeHospital readmissionIndependent predictorsClinical outcomesPoor prognosisFunctional statusClinical covariatesClinical trajectoriesReadmissionLower riskPatientsConsiderable burdenCombined outcomeNatural historyMortalityDeathOutcomesWorsening renal function: What is a clinically meaningful change in creatinine during hospitalization with heart failure?
Smith GL, Vaccarino V, Kosiborod M, Lichtman JH, Cheng S, Watnick SG, Krumholz HM. Worsening renal function: What is a clinically meaningful change in creatinine during hospitalization with heart failure? Journal Of Cardiac Failure 2003, 9: 13-25. PMID: 12612868, DOI: 10.1054/jcaf.2003.3.Peer-Reviewed Original ResearchMeSH KeywordsAgedBiomarkersCohort StudiesConnecticutCreatinineFemaleFollow-Up StudiesHeart FailureHospitalizationHumansKidney DiseasesKidney Function TestsMaleMiddle AgedMultivariate AnalysisPredictive Value of TestsProspective StudiesRisk FactorsSensitivity and SpecificityStatistics as TopicStroke VolumeSurvival AnalysisConceptsCreatinine elevationRenal functionHeart failureAdverse outcomesRisk of deathNumber of patientsMagnitude of riskBaseline creatinineProspective cohortRisk factorsFunctional declineHigh riskPatientsCreatinineMortalityHospitalizationDeathDlImportant predictorRiskElevationMeaningful changeMaximum specificityOutcomesBetter definition
2002
Differences between African Americans and whites in the outcome of heart failure: Evidence for a greater functional decline in African Americans
Vaccarino V, Gahbauer E, Kasl SV, Charpentier PA, Acampora D, Krumholz HM. Differences between African Americans and whites in the outcome of heart failure: Evidence for a greater functional decline in African Americans. American Heart Journal 2002, 143: 1058-1067. PMID: 12075264, DOI: 10.1067/mhj.2002.122123.Peer-Reviewed Original ResearchMeSH KeywordsActivities of Daily LivingAgedAnalysis of VarianceBlack PeopleCohort StudiesFemaleHealth Services AccessibilityHeart FailureHospitalizationHumansIncomeMaleMiddle AgedOutcome Assessment, Health CareProportional Hazards ModelsProspective StudiesQuality of Health CareSocioeconomic FactorsWhite PeopleConceptsGreater functional declineHeart failureCare indicatorsFunctional declineAfrican AmericansSelf-reported health statusSigns of decompensationDecompensated heart failureHistory of hypertensionProspective cohort studyVentricular ejection fractionDaily living functionAfrican American patientsDaily living functioningRenal insufficiencyBaseline characteristicsCohort studyConsecutive patientsEjection fractionHospital admissionFunctional statusAmerican patientsPoor courseLiving functioningHigh risk
2001
Depressive symptoms and risk of functional decline and death in patients with heart failure
Vaccarino V, Kasl S, Abramson J, Krumholz H. Depressive symptoms and risk of functional decline and death in patients with heart failure. Journal Of The American College Of Cardiology 2001, 38: 199-205. PMID: 11451275, DOI: 10.1016/s0735-1097(01)01334-1.Peer-Reviewed Original ResearchConceptsCoronary heart diseaseHeart failureDepressive symptomsFunctional declineCombined end pointDecompensated heart failureBaseline functional statusNegative prognostic factorGeriatric Depression ScaleYears of ageIntermediate riskHospital admissionPrognostic factorsPoor outcomePoor prognosisFunctional statusMedical historyHeart diseaseRisk factorsClinical severityDepression ScaleDaily livingHigh riskPatientsMultivariate analysis