2020
The National Institutes of Health funding for clinical research applying machine learning techniques in 2017
Annapureddy AR, Angraal S, Caraballo C, Grimshaw A, Huang C, Mortazavi BJ, Krumholz HM. The National Institutes of Health funding for clinical research applying machine learning techniques in 2017. Npj Digital Medicine 2020, 3: 13. PMID: 32025574, PMCID: PMC6994580, DOI: 10.1038/s41746-020-0223-9.Peer-Reviewed Original Research
2015
Post-market clinical research conducted by medical device manufacturers: a cross-sectional survey
Ross JS, Blount KL, Ritchie JD, Hodshon B, Krumholz HM. Post-market clinical research conducted by medical device manufacturers: a cross-sectional survey. Medical Devices Evidence And Research 2015, Volume 8: 241-249. PMID: 26060416, PMCID: PMC4454210, DOI: 10.2147/mder.s82964.Peer-Reviewed Original Research
2014
High Incarceration Rates Among Black Men Enrolled In Clinical Studies May Compromise Ability To Identify Disparities
Wang EA, Aminawung JA, Wildeman C, Ross JS, Krumholz HM. High Incarceration Rates Among Black Men Enrolled In Clinical Studies May Compromise Ability To Identify Disparities. Health Affairs 2014, 33: 848-855. PMID: 24799583, PMCID: PMC4065793, DOI: 10.1377/hlthaff.2013.1325.Peer-Reviewed Original ResearchConceptsClinical studiesHealth outcomesBlack menProspective clinical studyObservational clinical researchBlood InstituteNational HeartClinical researchWhite womenRacial disparitiesWhite menMinimal riskMenBlack womenHigh rateJail inmatesMinority populationsWomenOutcomesEffects of incarcerationImpact of incarcerationHigh incarceration ratesIncarcerationLungFollow
2013
Network News: Powering Clinical Research
Selby JV, Krumholz HM, Kuntz RE, Collins FS. Network News: Powering Clinical Research. Science Translational Medicine 2013, 5: 182fs13. PMID: 23612587, PMCID: PMC5101932, DOI: 10.1126/scitranslmed.3006298.Peer-Reviewed Original ResearchEthical Oversight: Serving the Best Interests of Patients
Selby JV, Krumholz HM. Ethical Oversight: Serving the Best Interests of Patients. The Hastings Center Report 2013, 43: s34-s36. PMID: 23315893, DOI: 10.1002/hast.138.Peer-Reviewed Original Research
2006
Does Random Treatment Assignment Cause Harm to Research Participants?
Gross CP, Krumholz HM, Van Wye G, Emanuel EJ, Wendler D. Does Random Treatment Assignment Cause Harm to Research Participants? PLOS Medicine 2006, 3: e188. PMID: 16719548, PMCID: PMC1470665, DOI: 10.1371/journal.pmed.0030188.Peer-Reviewed Original ResearchConceptsClinical outcomesTreatment assignmentRCT participantsClinical trialsTrial participantsRandom treatment assignmentPrimary study outcomeMeeting eligibility criteriaImproved patient outcomesSimilar health statusSubstandard medical careBaseline characteristicsPatient groupPatient outcomesEligibility criteriaHealth outcomesHealth statusEligible manuscriptsMedical careSystematic reviewSame interventionClinical researchStudy outcomesOutcomesSignificant differences
2003
Race, ethnic group, and clinical research
Rathore SS, Krumholz HM. Race, ethnic group, and clinical research. The BMJ 2003, 327: 763. PMID: 14525851, PMCID: PMC214058, DOI: 10.1136/bmj.327.7418.763.Peer-Reviewed Original Research