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In obese individuals, cellular "doormen" open the gates far too wide in certain key fat cells, known as visceral fat cells, letting in too many carbohydrates without first burning off lipids. This leads to a ballooning of the size of visceral fat cells in the belly.
Dr. Matthew Rodeheffer seeks clues to preventing and treating obesity by studying sex differences in cell formation.
Matthew Rodeheffer, associate professor of comparative medicine, was honored at the third annual Helmholtz-Nature Medicine Diabetes Conference in Munich on Sept. 21 for his groundbreaking research into how fat mass can lead to diabetes and heart disease.
A study led by Ryan Berry GRD ’15 and associate research scientist Matthew Rodeheffer from the Yale School of Medicine determined that a specific type of cell, the CD24+ cell, differentiates into fat cells in mice. This development answers many questions regarding the origins of body fat, which is the key factor in highly prevalent conditions such as diabetes and obesity.
Once fat cells form, they might shrink during weight loss, but they do not disappear, a fact that has derailed many a diet. Yale researchers in the March 2 issue of the journal Nature Cell Biology describe how — and just how quickly — those fat cells are created in the first place.
In a Q&A, Mireille Serlie, MD, PhD, discusses the effects of eating patterns on the brain, the risks of being frequently exposed to high-sucrose and high-fat foods, and recommendations for adopting healthy eating habits.
In a Q&A, Ania Jastreboff, MD, PhD, discusses the barriers to treating obesity, benefits of clinical trials, and the new era of obesity medicine.
Ania Jastreboff, MD, PhD, Director, Yale Obesity Research Center (Y-Weight); Co-Director, Yale Center for Weight Management, is interviewed by WTNH-TV on muscle loss while losing weight.
Low albumin levels were associated with an increased rate of serious surgical complications and comorbidities.
Kasia Lipska, MD, MHS, was one of five experts invited to testify at the Senate Health, Education, Labor, and Pensions (HELP) Committee hearing on December 14, 2023.
Bariatric surgeon Dr. Neil Floch speaks with Kate Bauman about the treatments surrounding obesity.
Patients who could benefit from popular obesity and Type 2 diabetes drugs are unable to get them due to disparities.
The SELECT trial findings suggest a weight loss drug could lower the risk of heart disease by 20 percent.
The shifts in attitude about obesity can also be seen in the KFF survey, said Dr. Ania Jastreboff, an endocrinologist and obesity-medicine specialist at Yale University and a consultant for the makers of the new drugs. After decades of hearing that losing weight was just a matter of exerting willpower, most of the public is intensely interested in medical treatments.
Rachel Perry, PhD, assistant professor of medicine (endocrinology) and of cellular and molecular physiology, received the Endocrinology and Metabolism Section New Investigator Award from the American Physiological Society (APS) during its summit on April 21.
Sedentary time at an extraordinary level. Harlan Krumholz, MD , says we need a large-scale societal shift where daily movement is the norm.
In today’s health headlines, what to know about a new Omicron subvariant, and how Americans are snacking more than ever. What this means for our health, and the link between asthma and obesity. Dr. Nate Wood, Yale Medicine Internal Medicine specialist and instructor at Yale School of Medicine, discussed these topics.
Millions of U.S. adults who are overweight or obese are unable to afford the latest treatment in obesity medicine, a study by the Yale School of Medicine has found.
Harlan Krumholz joins Shep Smith to discuss new recommendations regarding aspirin and heart disease, and diabetes testing for obese adults age 35 and over.
Samoa has one of the highest prevalences of childhood obesity in the world. The Samoa Observer reports on the results of Courtney Choy's Brown University Department of Epidemiology doctoral dissertation, which finds a clear need for intervention before a child turns five, especially for Samoan children in urban areas, eating what has become the now-normal diet of imported and packaged foods. Interrupting this lifestyle could be an effective way to prevent obesity and related cardiometabolic diseases, Choy finds.