Bio Haven: How Yale and New Haven are building a future together
New Haven’s biotech community has seen fits and starts, but today it is achieving critical mass. Upwards of 50 biotech and medical device companies employ more than 5,000 people in greater New Haven. Yale School of Medicine has been instrumental in the communty's growth.
Research in the news: How a mutated gene wreaks havoc on white matter
An inherited disease of myelin marked by slow, progressive neurological impairment is caused by mutations of a gene that controls lipid metabolism, a finding that may shed insight into mechanisms to control the course of multiple sclerosis (MS), a Yale team has found.
Taking a productive alliance further
In 2011 the School of Medicine formed a research alliance with the biopharmaceutical company Gilead Sciences, Inc. to accelerate the discovery and development of new drugs to treat cancer. Called “transformative” by then-Yale President Richard C. Levin, the collaboration included an initial commitment of up to $40 million to support research at the medical school over four years. Now, almost four years into the collaboration, the commitment has been renewed for an additional three years and an a
Gene mutation linked to Tourette syndrome
So much of what we do, we do on autopilot—whether tying our shoes or driving the same route to work. Functioning on autopilot frees our attention for other things, but it can also entrap us in inflexible and uncontrollable behaviors that assume lives of their own, said Christopher Pittenger, M.D., Ph.D., associate professor of psychiatry and in the Child Study Center and assistant professor of psychology, who studies how the brain’s cortical-basal ganglia circuits help to automate routine behaviSource: Yale Medicine Magazine
A new device deciphers the language of cells
As inventions go, Yale biomedical engineer Rong Fan’s entry into the innovation sweepstakes is not much to look at. Fan’s device, impressively named a single-cell, 45-plex protein secretion measurement platform, seems to be little more than a sandwich of two sheets of clear silicon rubber the thickness of window glass, each sheet a bit smaller than a credit card and bearing a smaller, darker rectangle divided into 14 vertical sections.Source: Yale Medicine Magazine
Mapmakers of the living human body
Imagine trying to develop a drug and being able to see how and where that drug acts inside the body of a living person. Just such a tool is provided by positron emission tomography (PET), an imaging technology that is aiding drug development and research on the mechanisms of disease at the School of Medicine’s state-of-the-art PET Center.Source: Medicine@Yale
Junk no more: Yale’s contribution to mapping DNA’s “other 99 percent”
Yale scientists played a leading role in an international effort to map the 99 percent of the human genome that doesn’t produce proteins—perhaps ending the notion that those regions are “junk.” // Yale Medicine magazineSource: Yale Medicine Magazine
Yale alum builds a crucial bridge for psychiatry researchers
A $3 million gift to the Yale School of Medicine will establish a Psychiatry Research Scholars Program under the aegis of the Yale Child Study Center (CSC) and the Department of Psychiatry. The gift is from the family foundation of Herb Allison, M.B.A., a 1965 alumnus of Yale College.
Suicide Attempts of Muslims Compared With Other Religious Groups in the US
Hamada Hamid Altalib, DO, MPH, Associate Professor of Neurology and of Psychiatry, is the lead author of a new study comparing the prevalence of suicide attempts among Muslim adults compared with adults of other faith communities in the US. Altalib is part of the Yale Global Mental Health faculty leadership.Source: JAMA Psychiatry
Nyberg: Yale Researchers Studying Impact of Music on People with Psychosis
Adam Christoferson, founder and director of Musical Intervention, and Phil Corlett, PhD, Associate Professor of Psychiatry, talk with WTNH's Ann Nyberg about how Musical Intervention came to be and the work it does for those in recovery, how music bridges the gap, how the pair began their collaboration, and how they are studying the impact of music on people with psychotic illness.Source: WTNH
A Potential Case of Acute Ketamine Withdrawal: Clinical Implications for the Treatment of Refractory Depression
While clinical trials have shown meaningful antidepressant effects of ketamine in many patients with treatment-refractory illness, there remains concern that long-term ketamine treatment, especially of high frequency, could have negative health outcomes.Source: The American Journal of Psychiatry
Large Genomic Analysis Highlights COVID-19 Risk Factors
In March 2020, thousands of scientists around the world, including Yale's Renato Polimanti, PhD, MSc, Assistant Professor of Psychiatry; Gita Pathak, PhD, Postdoctoral Associate; and Frank Wendt, PhD, Postdoctoral Fellow, united to answer a pressing and complex question: What genetic factors influence why some COVID-19 patients develop severe, life-threatening disease requiring hospitalization, while others escape with mild symptoms or none at all?