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The Center maintains extensive facilities for electrophysiology studies, allowing the electrical activity of nerve cells to be examined under a wide variety of experimental conditions. Slice recording set-ups as well as rigs for spinal cord physiology and peripheral nerve physiology are available. For instance, researchers at the Center can monitor the recovery of nerve conduction following nerve injury, and the recovery of conduction in specific spinal cord tracts after injury and after various potential therapeutic manipulations.

Electrophysiology Image 1

Visualization of transfected neurons prepared for electrophysiological recording

There are also electrophysiology laboratories that are specially designed for the study of injured axons using techniques that include sucrose gap recordings, intra-axonal electrophysiology and voltage sensitive dyes.