Publications

Selected Publications

2018

Chiu CQ, Martenson JS, Yamazaki M, Natsume R, Sakimura K, Tomita S, Tavalin SJ, Higley MJ. Input-Specific NMDAR-Dependent Potentiation of Dendritic GABAergic Inhibition Neuron . 2018 Jan 17;97(2):368-377.e3. doi: 10.1016/j.neuron.2017.12.032. PMID: 29346754

Strittmatter SM.Emerging Mechanisms in Alzheimer's Disease and Their Therapeutic Implications Biol Psychiatry . 2018 Feb 15;83(4):298-299. doi: 10.1016/j.biopsych.2017.12.002. No abstract available. PMID: 29331211

Hawk JD, Calvo AC, Liu P, Almoril-Porras A, Aljobeh A, Torruella-Suárez ML, Ren I, Cook N, Greenwood J, Luo L, Wang ZW, Samuel ADT, Colón-Ramos DA. Integration of Plasticity Mechanisms within a Single Sensory Neuron of C. elegans Actuates a Memory.  Neuron
. 2018 Jan 17;97(2):356-367.e4. doi: 10.1016/j.neuron.2017.12.027. Epub 2018 Jan 4. PMID: 29307713Bessaih T, Higley MJ, Contreras D. Millisecond precision temporal encoding of stimulus features during cortically generated gamma oscillations in the rat somatosensory cortexJ Physiol. 2018 Feb 1;596(3):515-534. doi: 10.1113/JP275245. Epub 2018 Jan 9. PMID: 29265375

 


2017

Bian X, Saheki Y, De Camilli P.Ca2+ releases E-Syt1 autoinhibition to couple ER-plasma membrane tethering with lipid transport. EMBO J . 2018 Jan 17;37(2):219-234. doi: 10.15252/embj.201797359. Epub 2017 Dec 8. PMID: 29222176

Smith LM, Zhu R, Strittmatter SM. Disease-modifying benefit of Fyn blockade persists after washout in mouse Alzheimer's model. Neuropharmacology. 2018 Mar 1;130:54-61. doi: 10.1016/j.neuropharm.2017.11.042. Epub 2017 Nov 27. PubMed
PMID: 29191754; PubMed Central PMCID: PMC5743608. 

Lees JA, Zhang Y, Oh MS, Schauder CM, Yu X, Baskin JM, Dobbs K, Notarangelo LD, De Camilli P, Walz T, Reinisch KM. Architecture of the human PI4KIIIα lipid kinase complex. Proc Natl Acad Sci U S A. 2017 Dec 26;114(52):13720-13725. doi: 10.1073/pnas.1718471115. Epub 2017 Dec 11. PubMed PMID: 29229838; PubMed CentralPMCID: PMC5748228. 

Matos-Cruz V, Schneider ER, Mastrotto M, Merriman DK, Bagriantsev SN, Gracheva EO. Molecular Prerequisites for Diminished Cold Sensitivity in Ground Squirrels and Hamsters. Cell Rep. 2017 Dec 19;21(12):3329-3337. doi: 10.1016/j.celrep.2017.11.083. PubMed PMID: 29262313; PubMed Central PMCID: PMC5741102.

Bessaih T, Higley MJ, Contreras D. Millisecond precision temporal encoding of stimulus features during cortically generated gamma oscillations in the rat somatosensory cortex. J Physiol. 2017 Dec 18. doi: 10.1113/JP275245. [Epub ahead of print] PubMed PMID: 29265375.

Schneider ER, Anderson EO, Mastrotto M, Matson JD, Schulz VP, Gallagher PG, LaMotte RH, Gracheva EO, Bagriantsev SN. Molecular basis of tactile specialization in the duck bill. Proc Natl Acad Sci U S A. 2017 Dec 5;114(49):13036-13041. doi: 10.1073/pnas.1708793114. Epub 2017 Nov 6. PubMed PMID: 29109250; PubMed Central PMCID: PMC5724259. 

Tejwani L, Lim J. Hunting for the mutant without the MAP(K). Cell Res. 2017 Dec;27(12):1403-1404. doi: 10.1038/cr.2017.140. Epub 2017 Nov 14. PubMed PMID: 29134957; PubMed Central PMCID: PMC5717406.

Xuan Z, Manning L, Nelson J, Richmond JE, Colón-Ramos DA, Shen K, Kurshan PT. Clarinet (CLA-1), a novel active zone protein required for synaptic vesicle clustering and release. Elife. 2017 Nov 21;6. pii: e29276. doi: 10.7554/eLife.29276. PubMed PMID: 29160205; PubMed Central PMCID: PMC5728718.

Stefan CJ, Trimble WS, Grinstein S, Drin G, Reinisch K, De Camilli P, Cohen S, Valm AM, Lippincott-Schwartz J, Levine TP, Iaea DB, Maxfield FR, Futter CE, Eden ER, Judith D, van Vliet AR, Agostinis P, Tooze SA, Sugiura A, McBride HM. Membrane dynamics and organelle biogenesis-lipid pipelines and vesicular carriers. BMC Biol. 2017 Oct 31;15(1):102. doi: 10.1186/s12915-017-0432-0. PubMed PMID: 29089042; PubMed Central PMCID: PMC5663033.

Ma L, Cai Y, Li Y, Jiao J, Wu Z, O'Shaughnessy B, De Camilli P, Karatekin E, Zhang Y. Single-molecule force spectroscopy of protein-membrane interactions. Elife. 2017 Oct 30;6. pii: e30493. doi: 10.7554/eLife.30493. PubMed PMID: 29083305; PubMed Central PMCID: PMC5690283. 

Glogowska E, Schneider ER, Maksimova Y, Schulz VP, Lezon-Geyda K, Wu J, Radhakrishnan K, Keel SB, Mahoney D, Freidmann AM, Altura RA, Gracheva EO, Bagriantsev SN, Kalfa TA, Gallagher PG. Novel mechanisms of PIEZO1 dysfunction in hereditary xerocytosis. Blood. 2017 Oct 19;130(16):1845-1856. doi: 10.1182/blood-2017-05-786004. Epub 2017 Jul 17. PubMed PMID: 28716860; PubMed Central PMCID: PMC5649553.

Taguchi YV, Liu J, Ruan J, Pacheco J, Zhang X, Abbasi J, Keutzer J, Mistry PK, Chandra SS. Glucosylsphingosine Promotes α-Synuclein Pathology in Mutant GBA-Associated Parkinson's Disease. J Neurosci. 2017 Oct 4;37(40):9617-9631. doi: 10.1523/JNEUROSCI.1525-17.2017. Epub 2017 Aug 28. PubMed PMID: 28847804; PubMed Central PMCID: PMC5628407.

Hohendahl A, Talledge N, Galli V, Shen PS, Humbert F, De Camilli P, Frost A, Roux A. Structural inhibition of dynamin-mediated membrane fission by endophilin. Elife. 2017 Sep 21;6. pii: e26856. doi: 10.7554/eLife.26856. PubMed PMID: 28933693; PubMed Central PMCID: PMC5663480.  

Hirokawa T, Zou Y, Kurihara Y, Jiang Z, Sakakibara Y, Ito H, Funakoshi K, Kawahara N, Goshima Y, Strittmatter SM, Takei K. Regulation of axonal regeneration by the level of function of the endogenous Nogo receptor antagonist LOTUS. Sci Rep. 2017 Sep 21;7(1):12119. doi: 10.1038/s41598-017-12449-6. PubMed PMID: 28935984; PubMed Central PMCID: PMC5608707.

Salazar SV, Gallardo C, Kaufman AC, Herber CS, Haas LT, Robinson S, Manson JC, Lee MK, Strittmatter SM. Conditional Deletion of Prnp Rescues Behavioral and Synaptic Deficits after Disease Onset in Transgenic Alzheimer's Disease. JNeurosci. 2017 Sep 20;37(38):9207-9221. doi: 10.1523/JNEUROSCI.0722-17.2017. Epub 2017 Aug 21. PubMed PMID: 28842420; PubMed Central PMCID: PMC5607466.

Saheki Y, De Camilli P. The Extended-Synaptotagmins. Biochim Biophys Acta. 2017 Sep;1864(9):1490-1493. doi: 10.1016/j.bbamcr.2017.03.013. Epub 2017 Mar 28. Review. PubMed PMID: 28363589; PubMed Central PMCID: PMC5642939.

Martenson JS, Yamasaki T, Chaudhury NH, Albrecht D, Tomita S. Assembly rules for GABA(A) receptor complexes in the brain. Elife. 2017 Aug 17;6. pii: e30826. doi: 10.7554/eLife.27443. PubMed PMID: 28816653; PubMed Central PMCID: PMC5577914.

Batista-Brito R, Vinck M, Ferguson KA, Chang JT, Laubender D, Lur G, Mossner JM, Hernandez VG, Ramakrishnan C, Deisseroth K, Higley MJ, Cardin JA. Developmental Dysfunction of VIP Interneurons Impairs Cortical Circuits. Neuron. 2017 Aug 16;95(4):884-895.e9. doi: 10.1016/j.neuron.2017.07.034. PubMed PMID: 28817803; PubMed Central PMCID: PMC5595250.

Brown FC, Collett M, Tremblay CS, Rank G, De Camilli P, Booth CJ, Bitoun M, Robinson PJ, Kile BT, Jane SM, Curtis DJ. Loss of Dynamin 2 GTPase function results in microcytic anaemia. Br J Haematol. 2017 Aug;178(4):616-628. doi: 10.1111/bjh.14709. Epub 2017 May 3. PubMed PMID: 28466468. 

Tomita S, Bloodgood BL. Editorial overview: Molecular neuroscience 2017. Curr Opin Neurobiol. 2017 Aug;45:A1-A4. doi: 10.1016/j.conb.2017.07.002. Epub 2017 Jul 20. PubMed PMID: 28736237.

Nakamura F, Okada T, Shishikura M, Uetani N, Taniguchi M, Yagi T, Iwakura Y, Ohshima T, Goshima Y, Strittmatter SM. Protein Tyrosine Phosphatase δ Mediates the Sema3A-Induced Cortical Basal Dendritic Arborization through the Activation of Fyn Tyrosine Kinase. J Neurosci. 2017 Jul 26;37(30):7125-7139. doi: 10.1523/JNEUROSCI.2519-16.2017. Epub 2017 Jun 21. PubMed PMID: 28637841.

Klein ZA, Takahashi H, Ma M, Stagi M, Zhou M, Lam TT, Strittmatter SM. Loss of TMEM106B Ameliorates Lysosomal and Frontotemporal Dementia-Related Phenotypes in Progranulin-Deficient Mice. Neuron. 2017 Jul 19;95(2):281-296.e6. doi: 10.1016/j.neuron.2017.06.026. PubMed PMID: 28728022; PubMed Central PMCID: PMC5558861.

Haas LT, Salazar SV, Smith LM, Zhao HR, Cox TO, Herber CS, Degnan AP, Balakrishnan A, Macor JE, Albright CF, Strittmatter SM. Silent Allosteric Modulation of mGluR5 Maintains Glutamate Signaling while Rescuing Alzheimer's Mouse Phenotypes. Cell Rep. 2017 Jul 5;20(1):76-88. doi: 10.1016/j.celrep.2017.06.023. PubMed PMID: 28683325; PubMed Central PMCID: PMC5547898. 

Heiss JK, Barrett J, Yu Z, Haas LT, Kostylev MA, Strittmatter SM. Early Activation of Experience-Independent Dendritic Spine Turnover in a Mouse Model of Alzheimer's Disease. Cereb Cortex. 2017 Jul 1;27(7):3660-3674. doi: 10.1093/cercor/bhw188. PubMed PMID: 27365298.

Dell'Anno MT, Strittmatter SM. Rewiring the spinal cord: Direct and indirect strategies. Neurosci Lett. 2017 Jun 23;652:25-34. doi: 10.1016/j.neulet.2016.12.002. Epub 2016 Dec 19. Review. PubMed PMID: 28007647; PubMed Central PMCID: PMC5466898.

Saheki Y, De Camilli P. Endoplasmic Reticulum-Plasma Membrane Contact Sites. Annu Rev Biochem. 2017 Jun 20;86:659-684. doi:10.1146/annurev-biochem-061516-044932. Epub 2017 Feb 23. Review. PubMed PMID:28301744.

Wu Y, Whiteus C, Xu CS, Hayworth KJ, Weinberg RJ, Hess HF, De Camilli P. Contacts between the endoplasmic reticulum and other membranes in neurons. Proc Natl Acad Sci U S A. 2017 Jun 13;114(24):E4859-E4867. doi: 10.1073/pnas.1701078114. Epub 2017 May 30. PubMed PMID: 28559323; PubMed Central PMCID: PMC5474793.

Gorenberg EL, Chandra SS. The Role of Co-chaperones in Synaptic Proteostasis and Neurodegenerative Disease. Front Neurosci. 2017 May 19;11:248. doi: 10.3389/fnins.2017.00248. eCollection 2017. Review. PubMed PMID: 28579939; PubMed Central PMCID: PMC5437171.

Guo S, Lai C, Wu C, Cen G; Alzheimer's Disease Neuroimaging Initiative. Conversion Discriminative Analysis on Mild Cognitive Impairment Using MultipleCortical Features from MR Images. Front Aging Neurosci. 2017 May 18;9:146. doi:10.3389/fnagi.2017.00146. eCollection 2017. Erratum in: Front Aging Neurosci. 2017 Sep 05;9:293. PubMed PMID: 28572766; PubMed Central PMCID: PMC5435825. 

Ardiel EL, Kumar A, Marbach J, Christensen R, Gupta R, Duncan W, Daniels JS, Stuurman N, Colón-Ramos D, Shroff H. Visualizing Calcium Flux in Freely Moving Nematode Embryos. Biophys J. 2017 May 9;112(9):1975-1983. doi: 10.1016/j.bpj.2017.02.035. PubMed PMID: 28494967; PubMed Central PMCID: PMC5425378. 

Takahashi H, Klein ZA, Bhagat SM, Kaufman AC, Kostylev MA, Ikezu T, Strittmatter SM; Alzheimer’s Disease Neuroimaging Initiative. Opposing effects of progranulin deficiency on amyloid and tau pathologies via microglial TYROBP network. Acta Neuropathol. 2017 May;133(5):785-807. doi: 10.1007/s00401-017-1668-z. Epub 2017 Jan 9. PubMed PMID: 28070672; PubMed Central PMCID: PMC5391267.

Smith LM, Strittmatter SM. Binding Sites for Amyloid-β Oligomers and Synaptic Toxicity. Cold Spring Harb Perspect Med. 2017 May 1;7(5). pii: a024075. doi: 10.1101/cshperspect.a024075. Review. PubMed PMID: 27940601; PubMed Central PMCID: PMC5411685.

Inoue K, Balkin DM, Liu L, Nandez R, Wu Y, Tian X, Wang T, Nussbaum R, DeCamilli P, Ishibe S. Kidney Tubular Ablation of Ocrl/Inpp5b Phenocopies Lowe Syndrome Tubulopathy. J Am Soc Nephrol. 2017 May;28(5):1399-1407. doi: 10.1681/ASN.2016080913. Epub 2016 Nov 28. PubMed PMID: 27895154; PubMed Central PMCID: PMC5407733.

Fink KL, López-Giráldez F, Kim IJ, Strittmatter SM, Cafferty WBJ. Identification of Intrinsic Axon Growth Modulators for Intact CNS Neurons after Injury. Cell Rep. 2017 Mar 14;18(11):2687-2701. doi: 10.1016/j.celrep.2017.02.058. PubMed PMID: 28297672; PubMed Central PMCID: PMC5389739.

Milovanovic D, De Camilli P. Synaptic Vesicle Clusters at Synapses: A Distinct Liquid Phase? Neuron. 2017 Mar 8;93(5):995-1002. doi: 10.1016/j.neuron.2017.02.013. Review. PubMed PMID: 28279363; PubMed CentralPMCID: PMC5347463.

Yamasaki T, Hoyos-Ramirez E, Martenson JS, Morimoto-Tomita M, Tomita S. GARLH Family Proteins Stabilize GABA(A) Receptors at Synapses. Neuron. 2017 Mar 8;93(5):1138-1152.e6. doi: 10.1016/j.neuron.2017.02.023. PubMed PMID: 28279354; PubMed Central PMCID: PMC5347473.

Cao M, Wu Y, Ashrafi G, McCartney AJ, Wheeler H, Bushong EA, Boassa D, Ellisman MH, Ryan TA, De Camilli P. Parkinson Sac Domain Mutation in Synaptojanin 1 Impairs Clathrin Uncoating at Synapses and Triggers Dystrophic Changes in Dopaminergic Axons. Neuron. 2017 Feb  22;93(4):882-896.e5. doi: 10.1016/j.neuron.2017.01.019. PubMed PMID: 28231468; PubMed Central PMCID:PMC5340420.

Salazar SV, Strittmatter SM. Cellular prion protein as a receptor for amyloid-β oligomers in Alzheimer's disease. Biochem Biophys Res Commun. 2017 Feb 19;483(4):1143-1147. doi: 10.1016/j.bbrc.2016.09.062. Epub 2016 Sep 14. Review. PubMed PMID: 27639648; PubMed Central PMCID: PMC5303667.

Lees JA, Messa M, Sun EW, Wheeler H, Torta F, Wenk MR, De Camilli P, Reinisch KM. Lipid transport by TMEM24 at ER-plasma membrane contacts regulates pulsatile insulin secretion. Science. 2017 Feb 17;355(6326). pii: eaah6171. doi: 10.1126/science.aah6171. PubMed PMID: 28209843; PubMed Central PMCID: PMC5414417.

Vargas KJ, Schrod N, Davis T, Fernandez-Busnadiego R, Taguchi YV, Laugks U, Lucic V, Chandra SS. Synucleins Have Multiple Effects on Presynaptic Architecture. Cell Rep. 2017 Jan 3;18(1):161-173. doi: 10.1016/j.celrep.2016.12.023. PubMed PMID: 28052246; PubMed Central PMCID: PMC5510332.

Strittmatter S. Undervaluation of suffering of experimental animals inGermany. ALTEX. 2017;34(3):435-438. PubMed PMID: 28735338.

Byrne AB, Hammarlund M. Axon regeneration in C. elegans: Worming our way to mechanisms of axon regeneration. Exp Neurol. 2017 Jan;287(Pt 3):300-309. doi: 10.1016/j.expneurol.2016.08.015. Epub 2016 Aug 26. Review. PubMed PMID: 27569538; PubMed Central PMCID: PMC5136328.

Levin R, Hammond GR, Balla T, De Camilli P, Fairn GD, Grinstein S. Multiphasic dynamics of phosphatidylinositol 4-phosphate during phagocytosis. Mol Biol Cell. 2017 Jan 1;28(1):128-140. doi: 10.1091/mbc.E16-06-0451. Epub 2016 Nov 9. PubMed PMID: 28035045; PubMed Central PMCID: PMC5221617.