2024
0488 Exploring Study Recruitment Trends in the Acute Post-Stroke Setting
Schwarz J, Masroor K, Radulescu R, Tsang S, Sheth K, Redeker N, Yaggi H, Geer J. 0488 Exploring Study Recruitment Trends in the Acute Post-Stroke Setting. Sleep 2024, 47: a210-a210. DOI: 10.1093/sleep/zsae067.0488.Peer-Reviewed Original ResearchContinuous positive airway pressureObstructive sleep apneaPositive airway pressureAcute ischemic strokeAirway pressureUpper airway closureSleep-disordered breathingYale-New Haven HospitalCerebral blood flowOSA screeningOSA treatmentSleep apneaImpact cerebral blood flowAcademic medical centerSympathetic activityClinical trialsPatient populationHemodynamic changesRisk factorsPatientsFunctional recoveryExclusion criteriaAirway closureCardiovascular diseaseBlood flow0486 Performing Polysomnography in the Acute Post-stroke Setting
Masroor K, Schwarz J, Radulescu R, Tsang S, Sheth K, Redeker N, Yaggi H, Geer J. 0486 Performing Polysomnography in the Acute Post-stroke Setting. Sleep 2024, 47: a209-a209. DOI: 10.1093/sleep/zsae067.0486.Peer-Reviewed Original ResearchObstructive sleep apneaSleep apneaRates of obstructive sleep apneaSymptoms of obstructive sleep apneaSevere obstructive sleep apneaObstructive sleep apnea diagnosisAcute settingSleep-disordered breathingPercentage of patientsProportion of patientsYale-New Haven HospitalAHI cutoffOSA prevalenceOSA diagnosisPreventing recurrent strokeImprove stroke recoveryPolysomnography testNew Haven HospitalPolysomnographyScreening patientsTherapeutic windowApneaPatientsRisk factorsMedical records0722 Clinical, Demographic, Functional, and Symptom Correlates of COMISA in Stable Heart Failure
LaFleur K, Jeon S, Wang Z, Conley S, Redeker N. 0722 Clinical, Demographic, Functional, and Symptom Correlates of COMISA in Stable Heart Failure. Sleep 2024, 47: a309-a309. DOI: 10.1093/sleep/zsae067.0722.Peer-Reviewed Original ResearchApnea-hypopnea indexHeart failureNormal sleepSleep-disordered breathingStable chronic HFStable heart failureHypopnea indexDisordered breathingChronic HFDemographic characteristicsObjective sleep characteristicsStable HFCOMISAObservational studyStudy of sleepSymptom correlationMaintaining sleepSleep characteristicsChi-squareSleepSecondary analysisInsomniaNormal sleepersSymptomsRiskImpact of Sleep Disorders and Disturbed Sleep on Brain Health: A Scientific Statement From the American Heart Association
Gottesman R, Lutsey P, Benveniste H, Brown D, Full K, Lee J, Osorio R, Pase M, Redeker N, Redline S, Spira A, Hypertension O. Impact of Sleep Disorders and Disturbed Sleep on Brain Health: A Scientific Statement From the American Heart Association. Stroke 2024, 55: e61-e76. PMID: 38235581, DOI: 10.1161/str.0000000000000453.Peer-Reviewed Original ResearchConceptsBrain healthSleep disordersDisturbed sleepDevelopment of sleep disordersCognitive outcomesImpact of sleep disordersDevelopment of Alzheimer's diseaseSleep disturbanceBiological basisDisordersBrainSleepAlzheimer's disease-related dementiasAlzheimer's diseaseBenefits of treatmentEarly treatmentScientific statementAmerican Heart AssociationSleep-disordered breathingDementiaAlzheimer
2019
The Epidemiology of Patient‐Reported Hypersomnia in Persons With Advanced Age
Miner B, Gill TM, Yaggi HK, Redeker NS, Van Ness PH, Han L, Fragoso C. The Epidemiology of Patient‐Reported Hypersomnia in Persons With Advanced Age. Journal Of The American Geriatrics Society 2019, 67: 2545-2552. PMID: 31390046, PMCID: PMC6898735, DOI: 10.1111/jgs.16107.Peer-Reviewed Original ResearchConceptsSelf-reported sleep-disordered breathingRestless legs syndromeMean ESS scoreCommunity-dwelling personsESS scoreCross-sectional associationsAdvanced ageHypersomnia symptomsCentral nervous system depressant medicationsEpworth Sleepiness Scale scoreMini-Mental State Examination scoreEpidemiologic Studies-Depression scoreSelf-reported medical conditionsEpidemiology of patientsLow physical activitySleep-disordered breathingBody mass indexPhysical Activity ScalePrecipitating Events ProjectState Examination scoreInsomnia Severity IndexMultivariable regression modelsDepressant medicationsClinical characteristicsCross-sectional designChapter 5 Cardiovascular Disease
Redeker N. Chapter 5 Cardiovascular Disease. 2019, 99-120. DOI: 10.1016/b978-0-12-813014-8.00005-6.Peer-Reviewed Original ResearchCardiovascular diseaseSleep deficiencyExcess health care utilizationDevelopment of CVDSleep-disordered breathingCoronary heart diseaseHealth care utilizationRestless legs syndromeChronic cardiovascular diseasePoor sleep qualityLong sleep durationQuality of lifeDisease exacerbationDaytime symptomsHeart failureLegs syndromeHeart diseaseSleep qualitySleep durationClinical interventionsMajor causePopulation healthDiseaseRecent evidenceMorbidity
2018
Insomnia in Community‐Living Persons with Advanced Age
Miner B, Gill TM, Yaggi HK, Redeker NS, Van Ness PH, Han L, Fragoso CAV. Insomnia in Community‐Living Persons with Advanced Age. Journal Of The American Geriatrics Society 2018, 66: 1592-1597. PMID: 29785710, PMCID: PMC6167156, DOI: 10.1111/jgs.15414.Peer-Reviewed Original ResearchConceptsSelf-reported sleep-disordered breathingRestless legs syndromeInsomnia Severity IndexDepressive symptomsBaseline characteristicsOlder adultsCognitive impairmentAverage baseline characteristicsEpidemiology of insomniaChronic lung diseaseSleep-disordered breathingMultivariable regression modelsHigh medical burdenCurrent smokersLegs syndromeLung diseaseClinical correlatesDaytime sleepinessSleep disturbancesAdvanced ageMedical burdenMild severityCardiovascular diseaseDiagnostic confirmationHigh prevalence
2016
The Association between Nocturnal Cardiac Arrhythmias and Sleep-Disordered Breathing: The DREAM Study.
Selim BJ, Koo BB, Qin L, Jeon S, Won C, Redeker NS, Lampert RJ, Concato JP, Bravata DM, Ferguson J, Strohl K, Bennett A, Zinchuk A, Yaggi HK. The Association between Nocturnal Cardiac Arrhythmias and Sleep-Disordered Breathing: The DREAM Study. Journal Of Clinical Sleep Medicine 2016, 12: 829-37. PMID: 26951420, PMCID: PMC4877315, DOI: 10.5664/jcsm.5880.Peer-Reviewed Original ResearchConceptsSleep-disordered breathingNocturnal cardiac arrhythmiasIntraventricular conduction delayApnea-hypopnea indexCardiac arrhythmiasTwo-fold oddsModerate-severe sleep-disordered breathingSeverity of SDBSevere sleep-disordered breathingComplex ventricular ectopyMultiple cardiovascular comorbiditiesObstructive respiratory eventsClinic-based populationCross-sectional analysisCardiovascular comorbiditiesSDB patientsVentricular ectopySDB severityRespiratory eventsUnadjusted oddsSupraventricular tachycardiaCardiovascular diseaseArrhythmia subtypesArrhythmia riskConduction delayExcessive Daytime Sleepiness in Stroke Survivors
Ding Q, Whittemore R, Redeker N. Excessive Daytime Sleepiness in Stroke Survivors. Biological Research For Nursing 2016, 18: 420-431. PMID: 26792913, PMCID: PMC6344831, DOI: 10.1177/1099800415625285.Peer-Reviewed Original ResearchConceptsExcessive daytime sleepinessStroke survivorsDaytime sleepinessStroke survivors' qualityIndependent risk factorSleep-disordered breathingStroke patientsPrevalent symptomsRisk factorsInclusion criteriaSurvivors' qualityClinical practiceSurvivorsIntegrative reviewCognitive functioningOutcomesStrokeSymptomsSleepinessHarmful outcomesFunctional performanceObjective measuresMultidimensional constructEMBASEPatients
2015
The Determining Risk of Vascular Events by Apnea Monitoring (DREAM) study: design, rationale, and methods
Koo BB, Won C, Selim BJ, Qin L, Jeon S, Redeker NS, Bravata DM, Strohl KP, Concato J, Zinchuk AV, Yaggi HK. The Determining Risk of Vascular Events by Apnea Monitoring (DREAM) study: design, rationale, and methods. Sleep And Breathing 2015, 20: 893-900. PMID: 26642771, DOI: 10.1007/s11325-015-1254-3.Peer-Reviewed Original ResearchConceptsCardiovascular outcomesVascular eventsSleep architecturePrognostic modelRetrospective observational cohort studyMain primary outcomeMiddle-aged veteransTransient ischemic attackAcute coronary syndromeObservational cohort studyResultsThe study populationCongestive heart failureSleep-disordered breathingVA Patient Treatment FileVital Status filesPatient Treatment FileComputerized patient record systemVeterans Affairs centersPost-traumatic stress disorderIschemic attackCoronary syndromeCohort studySecondary outcomesComposite endpointGlycemic controlContributions of Comorbid Diabetes to Sleep Characteristics, Daytime Symptoms, and Physical Function Among Patients With Stable Heart Failure
Fritschi C, Redeker NS. Contributions of Comorbid Diabetes to Sleep Characteristics, Daytime Symptoms, and Physical Function Among Patients With Stable Heart Failure. The Journal Of Cardiovascular Nursing 2015, 30: 411-419. PMID: 25078876, PMCID: PMC4312262, DOI: 10.1097/jcn.0000000000000183.Peer-Reviewed Original ResearchConceptsStable heart failureDiabetes mellitusHeart failurePoor physical functioningHF patientsDaytime symptomsPhysical functionSleep disturbancesPhysical functioningSleep characteristicsSleep qualityNew York Heart Association classNew York Heart Association classificationSelf-reported physical functionPhysical component summary scoreSelf-reported sleep qualityComorbid diabetes mellitusRespiratory disturbance indexComponent summary scoresMedical Outcomes StudySleep-disordered breathingBody mass indexPhysical function measuresAdditive effectLower general health
2008
Challenges and Opportunities Associated With Studying Sleep in Critically Ill Adults
Redeker NS. Challenges and Opportunities Associated With Studying Sleep in Critically Ill Adults. AACN Advanced Critical Care 2008, 19: 178-185. PMID: 18560287, DOI: 10.1097/01.aacn.0000318121.49136.89.Peer-Reviewed Original ResearchConceptsSleep promotion interventionsCritical care settingIll patientsPromotion interventionsCare settingsSleep-disordered breathingCritical care environmentIll adultsFunctional outcomeNature of sleepPatient satisfactionSleep disturbancesClinical trialsStudy of sleepHealthcare resourcesSleep measurementsSleep deprivationSleepCare environmentPatientsCircadian rhythmInterventionCritical settingsNonrandom sampleSettingChallenges and Opportunities Associated With Studying Sleep in Critically Ill Adults
Redeker N. Challenges and Opportunities Associated With Studying Sleep in Critically Ill Adults. AACN Advanced Critical Care 2008, 19: 178-185. DOI: 10.4037/15597768-2008-2011.Peer-Reviewed Original ResearchSleep promotion interventionsCritical care settingIll patientsPromotion interventionsCare settingsSleep-disordered breathingHealth care resourcesCritical care environmentIll adultsFunctional outcomeNature of sleepPatient satisfactionSleep disturbancesClinical trialsStudy of sleepSleep measurementsSleep deprivationSleepCare environmentPatientsCircadian rhythmInterventionCritical settingsNonrandom sampleSetting