HOXA5 protein expression and genetic fate mapping show lineage restriction in the developing musculoskeletal system
Holzman MA, Bergmann JM, Feldman M, Landry-Truchon K, Jeannotte L, Mansfield JH. HOXA5 protein expression and genetic fate mapping show lineage restriction in the developing musculoskeletal system. The International Journal Of Developmental Biology 2018, 62: 785-796. PMID: 30604848, PMCID: PMC8783609, DOI: 10.1387/ijdb.180214jm.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBody PatterningGene Expression Regulation, DevelopmentalHomeodomain ProteinsMesodermMiceMice, TransgenicMusculoskeletal SystemOrganogenesisPhosphoproteinsSomitesTranscription FactorsConceptsLateral plate mesodermHOXA5 expressionSkeletal patterningPlate mesodermNon-cell autonomous functionCell-autonomous roleProtein expressionSatellite cell lineageLineage restrictionGenetic lineagesEmbryonic cellsCell lineagesLateral sclerotomeTissue specificitySomite stageSkeletal developmentLineagesAutonomous roleDirect roleMusculoskeletal morphologyTissue typesMesodermHOXA5SomitesAutonomous functions