2015
Prognostication of post-cardiac arrest coma: early clinical and electroencephalographic predictors of outcome
Sivaraju A, Gilmore EJ, Wira CR, Stevens A, Rampal N, Moeller JJ, Greer DM, Hirsch LJ, Gaspard N. Prognostication of post-cardiac arrest coma: early clinical and electroencephalographic predictors of outcome. Intensive Care Medicine 2015, 41: 1264-1272. PMID: 25940963, DOI: 10.1007/s00134-015-3834-x.Peer-Reviewed Original ResearchConceptsBetter outcomesPoor outcomeEpileptiform dischargesPost-cardiac arrest comatose patientsCritical care EEG terminologyPost-cardiac arrest comaMethodsProspective cohort studyContinuous EEG monitoringLow-voltage EEGPositive predictive valueAbsence of reactivityEEG terminologyCohort studySpontaneous circulationBrainstem reflexesClinical outcomesComatose patientsFalse positive ratePoor prognosisPrognostic significanceSuppression burstsClinical variablesClinical correlatesElectroencephalographic patternsElectroencephalographic predictors
2012
Impact of Prolonged Periodic Epileptiform Discharges on Coma Prognosis
Ong C, Gilmore E, Claassen J, Foreman B, Mayer SA. Impact of Prolonged Periodic Epileptiform Discharges on Coma Prognosis. Neurocritical Care 2012, 17: 39-44. PMID: 22700361, DOI: 10.1007/s12028-012-9728-7.Peer-Reviewed Original ResearchConceptsRecovery of consciousnessComatose patientsElectrographic seizuresCEEG monitoringEpileptiform dischargesAdmission Glasgow Coma Scale scoreGlasgow Coma Scale scoreHypoxic-ischemic encephalopathyGlasgow Outcome ScaleTime of dischargeContinuous EEG monitoringNumber of AEDsPeriodic epileptiform dischargesComa prognosisResultsMean ageMedian durationCommon diagnosisIntracerebral hemorrhageFocal hypermetabolismNeuro-ICUSubarachnoid hemorrhageFrequent findingOutcome ScaleClinical significanceLikelihood of survival