Chronic hypoxia modulates diaphragm function in the developing rat
Kass LJ, Bazzy AR. Chronic hypoxia modulates diaphragm function in the developing rat. Journal Of Applied Physiology 2001, 90: 2325-2329. PMID: 11356799, DOI: 10.1152/jappl.2001.90.6.2325.Peer-Reviewed Original ResearchMeSH KeywordsAgingAnimalsBody WeightChronic DiseaseDiaphragmElectric StimulationHypoxiaMuscle ContractionNeuromuscular JunctionRatsRats, Sprague-DawleySynaptic TransmissionConceptsOne-half relaxation timeNeuromuscular transmissionNerve stimulationChronic hypoxiaContraction timePhrenic nerve-hemidiaphragm preparationAge-matched controlsLower specific forceHypoxic diaphragmDiaphragm functionHemidiaphragm preparationHypoxic ratsHypoxic groupSpecific forceContractile propertiesControl groupRat diaphragmMaturation of mechanismsRatsGreater decreaseStimulationHypoxiaDiaphragmHypoxicDelays maturation