Clinical effectiveness and cost-effectiveness of a brief accessible cognitive behavioural therapy programme for stress in school-aged adolescents (BESST): a cluster randomised controlled trial in the UK
Brown J, James K, Lisk S, Shearer J, Byford S, Stallard P, Deighton J, Saunders D, Yarrum J, Fonagy P, Weaver T, Sclare I, Day C, Evans C, Carter B. Clinical effectiveness and cost-effectiveness of a brief accessible cognitive behavioural therapy programme for stress in school-aged adolescents (BESST): a cluster randomised controlled trial in the UK. The Lancet Psychiatry 2024, 11: 504-515. PMID: 38759665, DOI: 10.1016/s2215-0366(24)00101-9.Peer-Reviewed Original ResearchTreatment-as-usualCognitive behavioral therapyTreatment-as-usual groupCluster randomised controlled trialCognitive behavioral therapy workshopRandomised controlled trialsCognitive behavioural therapy programmeSymptoms of depressionBehavioural therapy programmePrimary intention-to-treat analysisSchools TrialIndex of Multiple DeprivationBehavioral therapyDepressive symptomsHealth Technology Assessment programmeSchool-aged adolescentsControlled trialsSelf-referral systemIntention-to-treat populationDiscover interventionsFull school yearMental healthDepressionTherapy programmeIntention-to-treat analysisBrief Educational Workshops in Secondary Schools Trial (BESST trial), a school-based cluster randomised controlled trial of the DISCOVER workshop for 16–18-year-olds: recruitment and baseline characteristics
James K, Lisk S, Payne-Cook C, Farishta Z, Farrelly M, Sheikh A, Slusarczyk M, Byford S, Day C, Deighton J, Evans C, Fonagy P, Saunders D, Sclare I, Shearer J, Stallard P, Weaver T, Yarrum J, Carter B, Brown J. Brief Educational Workshops in Secondary Schools Trial (BESST trial), a school-based cluster randomised controlled trial of the DISCOVER workshop for 16–18-year-olds: recruitment and baseline characteristics. Trials 2024, 25: 302. PMID: 38702825, PMCID: PMC11069277, DOI: 10.1186/s13063-024-08116-7.Peer-Reviewed Original ResearchConceptsSchool-based cluster randomised controlled trialWarwick-Edinburgh Mental Wellbeing ScaleCluster randomised controlled trialRandomised controlled trialsSchools TrialEducational workshopsMental Wellbeing ScaleControlled trialsOutcome data collectionSymptoms of depressionEthnic minority groupsSecondary schoolsReduce stigmaBaseline characteristicsPost-randomisationWellbeing ScaleSelf-referralSelf-referredLower wellbeingStudentsDistressed studentsEthnically diverse sampleSchoolWorkshop programmeGeneral wellbeingBrief Educational Workshops in Secondary Schools Trial (BESST): a cluster randomised controlled trial. Secondary analysis in those with elevated symptoms of depression
Lisk S, James K, Shearer J, Byford S, Stallard P, Deighton J, Saunders D, Yarrum J, Fonagy P, Weaver T, Sclare I, Day C, Evans C, Carter B, Brown J. Brief Educational Workshops in Secondary Schools Trial (BESST): a cluster randomised controlled trial. Secondary analysis in those with elevated symptoms of depression. BMJ Mental Health 2024, 27: e301192. PMID: 39209761, PMCID: PMC11367360, DOI: 10.1136/bmjment-2024-301192.Peer-Reviewed Original ResearchConceptsTreatment-as-usualCluster randomised controlled trialNational Health ServiceElevated symptoms of depressionQuality-adjusted life yearsElevated depressive symptomsSymptoms of depressionRandomised controlled trialsDepressive symptomsSchools TrialElevated symptomsEducational workshopsIntention-to-treatSecondary analysisPersonal Social Services perspectiveControlled trialsMultilevel linear regressionSocial Services perspectiveSchool-based interventionsCost-effectiveIntention-to-treat analysisOutcomes of participantsHealth servicesIncremental cost-effectiveness ratioClinically meaningful effect