A genetically informed Registered Report on adverse childhood experiences and mental health
Baldwin J, Sallis H, Schoeler T, Taylor M, Kwong A, Tielbeek J, Barkhuizen W, Warrier V, Howe L, Danese A, McCrory E, Rijsdijk F, Larsson H, Lundström S, Karlsson R, Lichtenstein P, Munafò M, Pingault J. A genetically informed Registered Report on adverse childhood experiences and mental health. Nature Human Behaviour 2022, 7: 269-290. PMID: 36482079, PMCID: PMC7614239, DOI: 10.1038/s41562-022-01482-9.Peer-Reviewed Original ResearchMeSH KeywordsAdverse Childhood ExperiencesChildHumansMental DisordersMental HealthParentsRisk FactorsUnited StatesConceptsMental health problemsAdverse childhood experiencesHealth problemsElevated riskMental healthGenetic confoundingChildhood experiencesPsychiatric vulnerabilityGenetic riskHigher polygenic scoresConfoundingChildrenPrevious associationsRiskGene-environment correlationSmall increaseAssociationHealthReportPolygenic scores