Yale Biostatistician Heping Zhang Delivers Prestigious Neyman Lecture
Heping Zhang, the Susan Dwight Bliss Professor of Biostatistics at the Yale School of Public Health, recently delivered the prestigious 2022 Neyman Memorial Lecture presented by the Institute of Mathematical Statistics (IMS) – one of the highest honors in statistical societies.
Major Gift Will Support an Innovative Brain Research Collaboration
The Swiss-based NOMIS Foundation is making a large five-year award for research into what makes the human brain unique. The research will be a collaboration between the laboratories of James P. Noonan, PhD, associate professor of genetics and of neuroscience at Yale School of Medicine, and Franck Polleux, PhD, professor of neuroscience at Columbia University and a member of that school’s Zuckerman Institute. Their combined mission is to understand the brain and mind.
Psychiatric disorders share an underlying genetic basis
Thomas Fernandez, MD, Assistant Professor in the Child Study Center and of Psychiatry, and Christopher Pittenger, MD, PhD, Associate Professor of Psychiatry, contributed to a paper published in Science that explores the genetic connections between disorders of the brain at a scale that far eclipses previous work on the subject.
Fernandez appointed to Health and Human Services panel
Thomas V. Fernandez, MD, Assistant Professor in the Child Study Center and of Psychiatry, has been appointed to serve as a member of the U.S. Department of Health and Human Services Behavioral Genetics and Epidemiology Study Section, Center for Scientific Review.
How autism may stem from problems with prediction
A ‘predictive coding’ theory of autism suggests that many of the condition’s hallmark traits occur when sensory input overrides expectation in the brain. Yale researchers, Katarzyna Chawarska, James McPartland and Philip Corlett, are featured.Source: Spectrum
Tourette disorder study judged among top 5 articles in 2017 by journal Neuron
Thomas V. Fernandez, MD, Assistant Professor in the Child Study Center and of Psychiatry, was co-lead author of a genetic coding study of Tourette disorder patients judged among the top five articles published in 2017 by the journal Neuron.
Lab-created mini-brains reveal how growing organ maintains neuronal balance
Scientists can now explore in a laboratory dish how the human brain develops by creating organoids — distinct, three-dimensional regions of the brain. In research published in Cell Stem Cell, Yale scientists coaxed early stage stem cells to create and fuse two types of organoids from different brain regions to show how the developing brain maintains proper balance of excitatory and inhibitory neurons.
Genetic basis of some cases of Tourette’s disorder discovered
Researchers have discovered four genes that are associated with a higher risk of developing Tourette’s disorder, although variants in as many as 400 genes contribute to the origins of the complex neurological condition, which is marked by motor and vocal tics.
Genetic Study Reveals Pathways That May be Disrupted in People with OCD
A genetic study of children with obsessive-compulsive disorder (OCD) and their parents, reported March 29, 2016 in Translational Psychiatry, has yielded important hints about genes and biological pathways that may be involved in the disorder.Source: Brain and Behavior Research Foundation
Genomic analysis pinpoints a potential target for treatment of Down syndrome
A study of changes in the patterns of gene activity in the brains of people with Down syndrome reveals that the formation of the brain’s white matter is affected throughout life, a finding that suggests treatment might be possible for the condition that affects 400,000 Americans.
Dr. Raman Nelakanti Awarded the 2023 Slayman Prize in Genetics
The Carolyn Slayman prize, awarded each year by the Department of Genetics, recognizes not only achievement in scientific research but also exceptional contributions to the scientific community. This year’s recipient is Dr. Raman Nelakanti, a geneticist who recently obtained his MD-PhD from the School of Medicine.
How genetics determine our life choices
It has been 20 years since the Human Genome Project was "completed". But it quickly became apparent that the efforts to sequence and map the human "book of life" was only just the beginning. Far from closing the question of what makes our bodies tick and why they do so differently, research on the human genome has revealed a far more complex picture than anyone could have imagined. We may not realize it, but it appears that many routine aspects of our daily lives might be partially driven by our genome.Source: BBC.com
Researchers explore the role of cellular plasticity in cancer
A recently published Yale study explored how cancer cell plasticity — which refers to the ability of cells to adapt their phenotypes in response to environmental signals without undergoing genetic alterations — might impact the development, progression and treatment of cancer.Source: Yale Daily News