Neurogenetics
Investigators in the neurogenetics pod focus on the genetic basis for neuropsychiatric disorders from gene discovery to using gene knock-outs in model species to test promising drug treatments. These investigators work in human and animal models and take a developmental perspective around when genes are and are not expressed and how clusters of genes are expressed together at key developmental periods for both normal and atypical development.
The Fernandez Lab works to uncover the genetic and epigenetic basis of multiple childhood neuropsychiatric disorders, including Obsessive-Compulsive Disorder, anxiety disorders, Tourette Syndrome, chronic tic disorders, motor stereotypies, and autism spectrum disorders.
- The Gupta Lab is investigating the genetic basis and neurobiology of ASD and rare neurogenetic syndromes. The lab is especially interested in regression in autism and is collaborating with other research groups at the Child Study Center to study late-onset, severe regressive autism known as Childhood Disintegrative Disorder (CDD).
- In the Hoffman lab, our goal is to understand the basic biological mechanisms underlying neurodevelopmental disorders, in particular autism spectrum disorders (ASD).
- Dr. Muhle and her team work to understand how genetic changes in people lead to autism spectrum disorder (ASD) and other neurodevelopmental disorders.