2000
Minimal Adenocarcinoma in Prostate Needle Biopsy Tissue
Thorson P, Humphrey P. Minimal Adenocarcinoma in Prostate Needle Biopsy Tissue. American Journal Of Clinical Pathology 2000, 114: 896-909. PMID: 11338479, DOI: 10.1309/kvpx-c1em-142l-1m6w.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinomaAtrophyBiopsy, NeedleDiagnosis, DifferentialHumansHyperplasiaImmunohistochemistryKeratinsMaleProstatic NeoplasmsConceptsNeedle biopsy tissueProstate needle biopsy tissueMinor diagnostic criteriaBiopsy tissueProstatic adenocarcinomaDiagnostic criteriaMinimal adenocarcinomaHigh-grade prostatic intraepithelial neoplasiaAtypical small acinar proliferationFocal glandular atypiaValuable adjunctive studySmall acinar proliferationProstatic intraepithelial neoplasiaAtypical adenomatous hyperplasiaConstellation of findingsIntermediate histologic gradeMajor diagnostic challengeWhole prostate glandWT1 Staining Reliably Differentiates Desmoplastic Small Round Cell Tumor From Ewing Sarcoma/Primitive Neuroectodermal Tumor
Hill D, Pfeifer J, Marley E, Dehner L, Humphrey P, Zhu X, Swanson P. WT1 Staining Reliably Differentiates Desmoplastic Small Round Cell Tumor From Ewing Sarcoma/Primitive Neuroectodermal Tumor. American Journal Of Clinical Pathology 2000, 114: 345-353. PMID: 10989634, DOI: 10.1093/ajcp/114.3.345.Peer-Reviewed Original ResearchMeSH KeywordsAbdominal NeoplasmsAdolescentAdultBiomarkers, TumorBlotting, SouthernChildChild, PreschoolDiagnosis, DifferentialDNA PrimersDNA-Binding ProteinsDNA, NeoplasmFemaleFibromatosis, AggressiveHumansImmunoenzyme TechniquesMaleNeuroectodermal Tumors, PrimitiveOncogene Proteins, FusionParotid NeoplasmsReverse Transcriptase Polymerase Chain ReactionSarcoma, EwingSequence Analysis, DNATranscription FactorsWT1 ProteinsConceptsDesmoplastic small round cell tumorSmall round cell tumorRound cell tumorEWS/PNETSarcoma/primitive neuroectodermal tumorPrimitive neuroectodermal tumorCell tumorsWT1 antibodyImmunohistochemical featuresNeuroectodermal tumorDiagnosis of DSRCTMalignant small round cell tumorEwing sarcoma/primitive neuroectodermal tumorEWS/PNETsRT-PCRReverse transcriptase-polymerase chain reaction analysisTranscriptase-polymerase chain reaction analysisWT1 stainingEWS-WT1 fusionChain reaction analysisPredictive valueTumorsAvailable tissue
1998
Pseudohyperplastic Prostatic Adenocarcinoma
Humphrey P, Kaleem Z, Swanson P, Vollmer R. Pseudohyperplastic Prostatic Adenocarcinoma. The American Journal Of Surgical Pathology 1998, 22: 1239-1246. PMID: 9777986, DOI: 10.1097/00000478-199810000-00009.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinomaAntibodies, MonoclonalBiopsy, NeedleDiagnosis, DifferentialHumansKeratinsMalePrecancerous ConditionsProstateProstatic HyperplasiaProstatic NeoplasmsConceptsCases of adenocarcinomaProstatic adenocarcinomaHyperplastic featuresNeedle biopsyProstate carcinoma growthUsual epithelial hyperplasiaProstatic needle biopsyLow Gleason scoreLow-grade carcinomaRadical prostatectomy specimensRadical prostatectomy tissueGleason pattern 2Cystic dilatationPathologic stagePrognostic implicationsTumor sizeGleason scoreHistologic gradePapillary infoldingsRadical prostatectomyUsual hyperplasiaHistologic variantsPrognostic informationProstatic carcinomaCarcinomatous foci
1997
Clear cell neoplasms of the endocrine system and thymus.
Wick M, Ritter J, Humphrey P, Nappi O. Clear cell neoplasms of the endocrine system and thymus. Seminars In Diagnostic Pathology 1997, 14: 183-202. PMID: 9279975.Peer-Reviewed Original ResearchConceptsEndocrine systemClear cell tumorsClear cell neoplasmsPancreatic endocrine neoplasmsThymic malignanciesThymic lesionsRare lesionsCell tumorsEndocrine tumorsAdrenocortical proliferationParathyroid tumorsCell neoplasmsDifferential diagnosisPituitary adenomasSurgical pathologistsEndocrine neoplasmsSimilar lesionsNeoplasmsLesionsTumorsUltrastructural featuresLymphoid differentiationThymusDiagnosisGerm cells
1993
Atypical adenomatous hyperplasia of the prostate: Morphologic criteria for its distinction from well-differentiated carcinoma
Bostwick D, Srigley J, Grignon D, Maksem J, Humphrey P, van der Kwast T, Bose D, Harrison J, Young R. Atypical adenomatous hyperplasia of the prostate: Morphologic criteria for its distinction from well-differentiated carcinoma. Human Pathology 1993, 24: 819-832. PMID: 8375853, DOI: 10.1016/0046-8177(93)90131-y.Peer-Reviewed Original ResearchMeSH KeywordsAdenomaCarcinomaDiagnosis, DifferentialHumansHyperplasiaImmunohistochemistryMaleObserver VariationProstateProstatic NeoplasmsConceptsAtypical adenomatous hyperplasiaDifferential Immunoreactivity of Epidermal Growth Factor Receptor in Benign, Dysplastic and Malignant Prostatic Tissues
Ibrahim G, Kerns B, MacDonald J, Ibrahim S, Kinney R, Humphrey P, Robertson C. Differential Immunoreactivity of Epidermal Growth Factor Receptor in Benign, Dysplastic and Malignant Prostatic Tissues. Journal Of Urology 1993, 149: 170-173. PMID: 7678041, DOI: 10.1016/s0022-5347(17)36032-9.Peer-Reviewed Original ResearchMeSH KeywordsAgedDiagnosis, DifferentialErbB ReceptorsHumansImmunohistochemistryMaleMiddle AgedProstatic HyperplasiaProstatic NeoplasmsConceptsBenign prostatic hyperplasiaEGFR immunoreactivityBasal cell layerLuminal cellsBasal cellsBPH tissueFactor receptorProstatic specific antigenMalignant prostatic tissueAreas of dysplasiaCell layerRadical prostatectomy specimensCap tissueEpidermal growth factor receptorGrowth factor receptorEGFR contentProstatic hyperplasiaImmunohistochemical examinationProstatic carcinomaProstatic specimensProstatectomy specimensProstatic tissue