2011
Fatty acids in the de novo lipogenesis pathway and risk of coronary heart disease: the Cardiovascular Health Study
Wu J, Lemaitre RN, Imamura F, King IB, Song X, Spiegelman D, Siscovick DS, Mozaffarian D. Fatty acids in the de novo lipogenesis pathway and risk of coronary heart disease: the Cardiovascular Health Study. American Journal Of Clinical Nutrition 2011, 94: 431-438. PMID: 21697077, PMCID: PMC3142722, DOI: 10.3945/ajcn.111.012054.Peer-Reviewed Original ResearchConceptsCoronary heart diseaseNonfatal myocardial infarctionSudden cardiac arrestFatal coronary heart diseaseTotal coronary heart diseaseIncident coronary heart diseaseDe novo lipogenesisHigh riskCHD eventsHeart diseaseMultivariable-adjusted Cox proportional hazardsCommunity-based prospective studySecondary analysisCardiovascular disease risk factorsCardiovascular Health StudyDisease risk factorsFatty acidsCox proportional hazardsDe novo lipogenesis pathwayCHD deathCHD outcomesProspective studyCardiac arrestMyocardial infarctionMedical records
2004
Sexual Orientation, Health Risk Factors, and Physical Functioning in the Nurses' Health Study II
Case P, Austin SB, Hunter DJ, Manson JE, Malspeis S, Willett WC, Spiegelman D. Sexual Orientation, Health Risk Factors, and Physical Functioning in the Nurses' Health Study II. Journal Of Women's Health 2004, 13: 1033-1047. PMID: 15665660, DOI: 10.1089/jwh.2004.13.1033.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlcohol DrinkingBisexualityBody Mass IndexBreast NeoplasmsCardiovascular DiseasesCross-Sectional StudiesDepressionFemaleHealth BehaviorHealth StatusHomosexuality, FemaleHumansLinear ModelsMental HealthMiddle AgedMultivariate AnalysisNurse CliniciansPrevalenceProspective StudiesRisk FactorsSmokingTime FactorsUnited StatesConceptsNurses' Health Study IIHealth Study IIBody mass indexRisk factorsHealth risk factorsHigh prevalenceRegion of residenceOverall cohortBreast cancerHealth statusHigher daily alcohol intakeCardiovascular disease risk factorsBreast cancer risk factorsHigher body mass indexStudy IIMultivariate prevalence ratiosDaily alcohol intakeDisease risk factorsUse of antidepressantsCancer risk factorsHealth-related functioningImportant risk factorMental health statusPoor mental healthBisexual women
2001
Plasma insulin, leptin, and soluble TNF receptors levels in relation to obesity-related atherogenic and thrombogenic cardiovascular disease risk factors among men
Chu N, Spiegelman D, Hotamisligil G, Rifai N, Stampfer M, Rimm E. Plasma insulin, leptin, and soluble TNF receptors levels in relation to obesity-related atherogenic and thrombogenic cardiovascular disease risk factors among men. Atherosclerosis 2001, 157: 495-503. PMID: 11472752, DOI: 10.1016/s0021-9150(00)00755-3.Peer-Reviewed Original ResearchConceptsCVD risk factorsRisk factorsPlasma insulinCVD riskHDL cholesterolInsulin levelsPlasma leptinAntigen levelsSoluble TNF receptor levelsCardiovascular disease risk factorsTissue plasminogen activator antigen levelsT-PA antigen levelsMetabolic cardiovascular syndromeHealth Professionals FollowIndependent risk factorDisease risk factorsEffect of obesitySoluble TNF receptorsTNF receptor levelsCardiovascular disease morbidityBody mass indexLevels of insulinProfessionals FollowLeptin levelsMass index