2019
Views of institutional leaders on maintaining humanism in today’s practice
Gilligan MC, Osterberg LG, Rider EA, Derse AR, Weil AB, Litzelman DK, Dunne DW, Hafler JP, Plews-Ogan M, Frankel RM, Branch WT. Views of institutional leaders on maintaining humanism in today’s practice. Patient Education And Counseling 2019, 102: 1911-1916. PMID: 31097330, DOI: 10.1016/j.pec.2019.04.025.Peer-Reviewed Original Research
2018
Healthcare at the Crossroads: The Need to Shape an Organizational Culture of Humanistic Teaching and Practice
Rider EA, Gilligan MC, Osterberg LG, Litzelman DK, Plews-Ogan M, Weil AB, Dunne DW, Hafler JP, May NB, Derse AR, Frankel RM, Branch WT. Healthcare at the Crossroads: The Need to Shape an Organizational Culture of Humanistic Teaching and Practice. Journal Of General Internal Medicine 2018, 33: 1092-1099. PMID: 29740787, PMCID: PMC6025655, DOI: 10.1007/s11606-018-4470-2.Peer-Reviewed Original Research
2017
How physicians draw satisfaction and overcome barriers in their practices: “It sustains me”
Branch WT, Weil AB, Gilligan MC, Litzelman DK, Hafler JP, Plews-Ogan M, Rider EA, Osterberg LG, Dunne D, Derse AR, Pittman JR, Frankel RM. How physicians draw satisfaction and overcome barriers in their practices: “It sustains me”. Patient Education And Counseling 2017, 100: 2320-2330. PMID: 28623052, DOI: 10.1016/j.pec.2017.06.004.Peer-Reviewed Original Research
2016
Sexually Transmitted Infections in the Context of HIV Disease: Clinical Implications.
Dunne DW. Sexually Transmitted Infections in the Context of HIV Disease: Clinical Implications. Topics In Antiviral Medicine 2016, 24: 111-114. PMID: 27841982, PMCID: PMC6148914.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2014
Lifestyle Factors and Primary Care Specialty Selection
Clinite KL, DeZee KJ, Durning SJ, Kogan JR, Blevins T, Chou CL, Diemer G, Dunne DW, Fagan MJ, Hartung PJ, Kazantsev SM, Mechaber HF, Paauw DS, Wong JG, Reddy ST. Lifestyle Factors and Primary Care Specialty Selection. Academic Medicine 2014, 89: 1483-1489. PMID: 25250748, DOI: 10.1097/acm.0000000000000487.Peer-Reviewed Original Research
2013
Primary Care, the ROAD Less Traveled
Clinite KL, Reddy ST, Kazantsev SM, Kogan JR, Durning SJ, Blevins T, Chou CL, Diemer G, Dunne DW, Fagan MJ, Hartung PJ, Mechaber HF, Paauw DS, Wong JG, DeZee KJ. Primary Care, the ROAD Less Traveled. Academic Medicine 2013, 88: 1522-1528. PMID: 23969353, DOI: 10.1097/acm.0b013e3182a316eb.Peer-Reviewed Original ResearchMyD88 Deficiency Markedly Worsens Tissue Inflammation and Bacterial Clearance in Mice Infected with Treponema pallidum, the Agent of Syphilis
Silver AC, Dunne DW, Zeiss CJ, Bockenstedt LK, Radolf JD, Salazar JC, Fikrig E. MyD88 Deficiency Markedly Worsens Tissue Inflammation and Bacterial Clearance in Mice Infected with Treponema pallidum, the Agent of Syphilis. PLOS ONE 2013, 8: e71388. PMID: 23940747, PMCID: PMC3734110, DOI: 10.1371/journal.pone.0071388.Peer-Reviewed Original ResearchConceptsMyD88-deficient miceTreponema pallidumMyD88-deficient animalsResistance of miceToll-like receptorsWild-type miceMyD88-deficient macrophagesMacrophage-mediated clearanceHigh pathogen burdenMyD88 deficiencySpirochete Treponema pallidumWT miceTissue infiltratesBacterial clearanceExtensive inflammationTissue inflammationPlasma cellsControl animalsWT macrophagesMost TLRsAnimal modelsMixed mononuclearPathogen burdenMiceT. pallidum
2010
Increased TLR4 Expression and Downstream Cytokine Production in Immunosuppressed Adults Compared to Non-Immunosuppressed Adults
Dunne DW, Shaw A, Bockenstedt LK, Allore HG, Chen S, Malawista SE, Leng L, Mizue Y, Piecychna M, Zhang L, Towle V, Bucala R, Montgomery RR, Fikrig E. Increased TLR4 Expression and Downstream Cytokine Production in Immunosuppressed Adults Compared to Non-Immunosuppressed Adults. PLOS ONE 2010, 5: e11343. PMID: 20596538, PMCID: PMC2893205, DOI: 10.1371/journal.pone.0011343.Peer-Reviewed Original ResearchConceptsNon-immunosuppressed adultsMIF levelsImmunosuppressive medicationsAutoimmune diseasesIL-8Cytokine productionMonocyte Toll-like receptor (TLR) expressionInnate immunityToll-like receptor expressionEnhanced innate immune responseAltered host immunityAutoimmune disease groupDownstream cytokine productionNon-immunosuppressed individualsUnderlying autoimmune diseaseFeatures of patientsHuman peripheral blood monocytesTLR4 surface expressionCytokine IL-8Number of patientsSurface expressionPeripheral blood monocytesInnate immune responseRisk of infectionImmunosuppressed adults
2005
Condom effectiveness for prevention of Chlamydia trachomatis infection
Niccolai LM, Rowhani-Rahbar A, Jenkins H, Green S, Dunne DW. Condom effectiveness for prevention of Chlamydia trachomatis infection. Sexually Transmitted Infections 2005, 81: 323. PMID: 16061540, PMCID: PMC1745001, DOI: 10.1136/sti.2004.012799.Peer-Reviewed Original ResearchConceptsC trachomatis infectionChlamydia trachomatis infectionTrachomatis infectionDisease-specific estimatesEffectiveness of condomsC trachomatisCondom usersMedical record databaseObserved protective effectConsistent condom usersInconsistent condom usersInfected partnerDisease clinicBody of evidenceInfection preventionProtective effectUnknown exposureRecord databaseCondom effectivenessInfectionCondomsClinicTrachomatisExposurePrevention
1996
Fungal peritonitis in a large chronic peritoneal dialysis population: a report of 55 episodes
Goldie S, Kiernan-Troidle L, Torres C, Gorban-Brennan N, Dunne D, Kliger A, Finkelstein F. Fungal peritonitis in a large chronic peritoneal dialysis population: a report of 55 episodes. American Journal Of Kidney Diseases 1996, 28: 86-91. PMID: 8712227, DOI: 10.1016/s0272-6386(96)90135-3.Peer-Reviewed Original ResearchConceptsDiagnosis of FPEpisodes of FPPrior antibiotic useFungal peritonitisTenckhoff catheterRisk factorsCPD therapyPeritonitis rateAntibiotic useChronic peritoneal dialysis therapyEnd-stage renal diseaseEarly catheter removalEpisodes of peritonitisPeritoneal dialysis populationPeritoneal dialysis therapyCatheter replacementTemporary hemodialysisCatheter removalDialysis populationCPD patientsRenal diseaseSerious complicationsDialysis therapyHigh morbidityTherapy 1
1993
Group B Streptococcal Meningitis in Adults
DUNNE D, QUAGLIARELLO V. Group B Streptococcal Meningitis in Adults. Medicine 1993, 72: 1-10. PMID: 8426534, DOI: 10.1097/00005792-199301000-00001.Peer-Reviewed Original ResearchConceptsGroup B streptococcal meningitisStreptococcal meningitisPercent of patientsCo-morbid illnessHours of symptomsBimodal age distributionConcomitant bacteremiaUnderlying illnessGBS infectionUncommon causeImmunocompromised hostOverall mortalityClinical presentationPyogenic organismsAdult casesRetrospective analysisMeningitisFrequent entityPatientsAdultsIllnessAge distributionHigh percentageBacteremiaImmunocompetent