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Brian Richard Smith, MD

Contact-PI of the Yale CTSA UL1

Professor of Laboratory Medicine, of Biomedical Engineering, of Medicine (Hematology) and of Pediatrics; Deputy Dean for Research, (Clinical and Translational); Director, Clinical Immunology Laboratory, Laboratory Medicine; Chair, Laboratory Medicine; Chief, Laboratory Medicine, Yale New Haven Hospital

Brian R. Smith MD is Deputy Dean for Clinical and Translational Research at the Yale School of Medicine, as well as Contact-PI of Yale's CTSA Award, Chair of the Department of Laboratory Medicine and Professor of Laboratory Medicine, Biomedical Engineering, Internal Medicine and Pediatrics at Yale University. He is the Chief of Laboratory Medicine and Attending Physician at Yale New Haven Hospital and also an attending physician at the Connecticut VA Medical Center and the Bridgeport Hospital.

Dr. Smith received his undergraduate degree summa cum laude from Princeton University, his medical degree from the Harvard Medical School, and his residency/fellowship training at The Brigham & Women’s Hospital, Boston Children’s Hospital, and Dana Farber Cancer Center. He is board certified in Pathology / Hematopathology and in Internal Medicine / Hematology-Oncology. In addition to his clinical work, Dr. Smith has an investigative interest in the inflammation-hemostasis interface, especially in relation to biomaterials, as well as in cellular immunotherapeutics, with over 175 publications. His work extends from basic wet bench research through clinical and epidemiological trials (T1-T4). He has been continuously funded by the NIH at the PI-level for over 35 years.

Dr. Smith also has educational responsibilities across the scientific pipeline from STEM high school student programs through undergraduate, graduate, and post-graduate training, for MDs, PhDs, and MD/PhDs. He is the initiator and long-standing PI of Laboratory Medicine’s post-doctoral T32 training program in Immunohematology and has personally mentored over 50 MD, MD/PhD, and PhD trainees, most of whom hold tenure-track positions at major research universities. Dr. Smith has extensive experience in the didactic aspects of comprehensive training and career development for clinician-scientists, having developed and published curricula in Laboratory Medicine, developed and published new physician-scientist training paradigms in his field.