When Cells Cycle Fast, Cancer Gets a Jumpstart
The progression of cancer has been studied extensively, and the key steps in this journey have been well mapped, at least in some solid tumors: Lesions to genes that confer risk of cancer accumulate and alter normal cell behaviors, giving rise, scientists believe, to early stage cancer cells that eventually swamp normal cells and become deadly.
Career Path: Women in Leadership at High Levels
Reaching high-level leadership positions in medicine—and specifically oncology—is not an easy task and requires significant time and dedication. For women, there are a host of additional challenges to contend with as they navigate their career.Source: Oncology Times
Role of Nutrient May Reveal Dietary Target in Fight Against Microbial Infections
A nutrient that is common in the human diet has been found to aid the survival of a cancer-causing bacterium, a new Yale study finds. The findings could reveal an important target for new drugs to tackle numerous infectious diseases in humans.Source: Yale West Campus
Smilow Cancer Hospital and Yale Police Team to Raise Breast Cancer Awareness
Members of Smilow Cancer Hospital and Yale Cancer Center spent time together on Friday, October 28 on the New Haven Green with members of the Yale Police Department – along with a special, pink-themed Yale Police SUV – to highlight Breast Cancer Awareness Month.
New Findings on Endometrial Cancer Treated With Pembrolizumab
New research from Yale Cancer Center reveals for the first time ever a differential clinical response to pembrolizumab in Lynch-like (mutated) vs methylated microsatellite instability-high (MSI-H) uterine cancer patients, increasing our understanding about the proportion of patients that derive benefit from immune checkpoint blockade.
Scientists researching new scientific approach to identify cancer origins
Previous studies have shown the connection between age, exposure to carcinogens and the risk of developing cancer due to the accumulation of mutations over time. Scientists from Yale University and Emmanuel College demonstrate a new scientific approach to determine the origins of different types of cancer. Jeffrey Townsend, YSPH Elihu Professor of Biostatistics and Ecology & Evolutionary Biology, was a co-author of the study.Source: The Daily Campus
Dhanpat Jain, MD, Joins Pathologists Nationwide in Calling for Continued Use of Remote Work in Clinical Laboratories and Pathology
A group of pathologists and laboratory leaders from across the U.S. is urging federal officials to continue certain regulatory exemptions implemented during the COVID-19 pandemic that allow the use of remote work in clinical laboratories and pathology.
Juan Vasquez, MD, Vidya Puthenpura, MD, MHS, FAAP, Awarded Grants to Further Pediatric Cancer Research
Two rising young stars of pediatric cancer research at Yale Cancer Center and Yale School of Medicine were awarded research grants from Hyundai Hope on Wheels program to further their work of improving outcomes and treatment for children diagnosed with cancer.
Pamela Kunz, MD on 1999 Simone’s Maxims
Pamela Kunz, MD, associate professor (medical oncology) and vice chief of Diversity, Equity, and Inclusion (medical oncology) writes that, “I distinctly remember being told by mentors to read the original 1999 Simone’s Maxims – as these maxims were put on a pedestal as the truths of how to navigate academic medicine.”
Fighting Breast and Ovarian Cancer With a Lupus Antibody
After discovering a specific lupus antibody that can penetrate cancer cells and, with a grant from Women's Health Research at Yale, showing it makes cancer cells vulnerable to standard treatments, Dr. Peter Glazer and his colleagues are moving a treatment to clinical trials.
Sex Differences in Gastrointestinal Cancer
With this year's Wendy U. and Thomas C. Naratil Pioneer Award and co-funding from the Yale Cancer Center, Dr. Pamela Kunz is conducting one of the first studies to examine sex differences in treating neuroendocrine neoplasms (NENs), a rare form of cancer often found in the gastrointestinal tract.
ExPath Grad Student Madeline Mayday Awarded Grant from the NIDDK Cooperative Centers of Excellence in Hematology
Madeline Mayday, BS, a fourth-year Experimental Pathology graduate student in the Laboratory of Diane Krause, MD, PhD, was recently awarded a 2022 National Institute of Diabetes and Digestive and Kidney Diseases Hematology Centers Program Type B Pilot and Feasibility grant
American Joint Committee on Cancer Names Dhanpat Jain, MD, to Editorial Board
Dhanpat Jain, MD, Professor of Pathology and of Medicine (Digestive Diseases), has been named by the American Joint Committee on Cancer (AJCC) to its editorial board for neuroendocrine tumors of the gastrointestinal tract.
Yale Pathologists Say AI, Algorithms in Digital Pathology Will Have Lasting Impact on Education, Clinical Practice
The continued emergence and development of artificial intelligence and algorithms in digital pathology will greatly impact the practice and teaching of pathology, Angelique W. Levi, MD, Associate Professor of Pathology, and Sudhir Perincheri, MBBS, PhD, Assistant Professor of Pathology, said in a recent podcast.
Yale Cancer Center Researchers Awarded Grants by Breast Cancer Research Foundation
The Breast Cancer Research Foundation (BCRF) Scientific Advisory Board and its Board of Directors recently announced its 2022 research grants, including six funded grants at Yale Cancer Center and Smilow Cancer Hospital awarded to Mehra Golshan, MD, MBA, Melinda Irwin, PhD, MPH, Ian Krop, MD, PhD, Lajos Pusztai, MD, DPhil, David Rimm, MD, PhD, and Eric Winer, MD to support their research.